Activity-dependent COX-2 proteolysis modulates aerobic respiration and proliferation in a prostaglandin-independent manner.

Autor: Hartal-Benishay LH; Department of Human Biology, Faculty of Natural Sciences, University of Haifa, Haifa 3103301 Israel., Tal S; Department of Human Biology, Faculty of Natural Sciences, University of Haifa, Haifa 3103301 Israel., Elkader AA; Department of Human Biology, Faculty of Natural Sciences, University of Haifa, Haifa 3103301 Israel., Ehsainieh O; Department of Human Biology, Faculty of Natural Sciences, University of Haifa, Haifa 3103301 Israel., Srouji-Eid R; Department of Human Biology, Faculty of Natural Sciences, University of Haifa, Haifa 3103301 Israel., Lavy T; Faculty of Biology, Technion - Israel Institute of Technology, Haifa 3200003, Israel., Kleifeld O; Faculty of Biology, Technion - Israel Institute of Technology, Haifa 3200003, Israel., Mikl M; Department of Human Biology, Faculty of Natural Sciences, University of Haifa, Haifa 3103301 Israel., Barki-Harrington L; Department of Human Biology, Faculty of Natural Sciences, University of Haifa, Haifa 3103301 Israel.

Publikováno v: IScience [iScience] 2024 Nov 17; Vol. 27 (12), pp. 111403. Date of Electronic Publication: 2024 Nov 17 (Print Publication: 2024).

Altered ubiquitin signaling induces Alzheimer's disease-like hallmarks in a three-dimensional human neural cell culture model.

Autor: Maniv I; Department of Biology, Technion Israel Institute of Technology, Haifa, 3200003, Israel., Sarji M; Department of Biology, Technion Israel Institute of Technology, Haifa, 3200003, Israel., Bdarneh A; Department of Biology, Technion Israel Institute of Technology, Haifa, 3200003, Israel., Feldman A; Department of Biology, Technion Israel Institute of Technology, Haifa, 3200003, Israel., Ankawa R; Department of Biology, Technion Israel Institute of Technology, Haifa, 3200003, Israel., Koren E; Department of Biology, Technion Israel Institute of Technology, Haifa, 3200003, Israel., Magid-Gold I; Department of Biology, Technion Israel Institute of Technology, Haifa, 3200003, Israel., Reis N; Department of Biology, Technion Israel Institute of Technology, Haifa, 3200003, Israel., Soteriou D; Department of Biology, Technion Israel Institute of Technology, Haifa, 3200003, Israel., Salomon-Zimri S; Department of Neurobiology, The George S. Wise Faculty of Life Sciences, The Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, 69978, Israel., Lavy T; Department of Biology, Technion Israel Institute of Technology, Haifa, 3200003, Israel., Kesselman E; The Wolfson Department of Chemical Engineering, The Technion Center for Electron Microscopy of Soft Matter, Technion Israel Institute of Technology, Haifa, 3200003, Israel., Koifman N; The Wolfson Department of Chemical Engineering, The Technion Center for Electron Microscopy of Soft Matter, Technion Israel Institute of Technology, Haifa, 3200003, Israel., Kurz T; School of Molecular Biosciences, University of Glasgow, Glasgow, G12 8QQ, Scotland, UK., Kleifeld O; Department of Biology, Technion Israel Institute of Technology, Haifa, 3200003, Israel., Michaelson D; Department of Neurobiology, The George S. Wise Faculty of Life Sciences, The Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, 69978, Israel., van Leeuwen FW; Department of Neuroscience, Maastricht University, 6229 ER, Maastricht, the Netherlands., Verheijen BM; Department of Biology, Technion Israel Institute of Technology, Haifa, 3200003, Israel.; Department of Neuroscience, Maastricht University, 6229 ER, Maastricht, the Netherlands., Fuchs Y; Department of Biology, Technion Israel Institute of Technology, Haifa, 3200003, Israel. yaronfox@gmail.com.; Augmanity, Rehovot, 7670308, Israel. yaronfox@gmail.com., Glickman MH; Department of Biology, Technion Israel Institute of Technology, Haifa, 3200003, Israel. glickman@technion.ac.il.

Publikováno v: Nature communications [Nat Commun] 2023 Sep 22; Vol. 14 (1), pp. 5922. Date of Electronic Publication: 2023 Sep 22.

In-Depth Characterization of Apoptosis N-Terminome Reveals a Link Between Caspase-3 Cleavage and Posttranslational N-Terminal Acetylation.

Autor: Hanna R; Faculty of Biology, Technion-Israel Institute of Technology, Haifa, Israel., Rozenberg A; Faculty of Biology, Technion-Israel Institute of Technology, Haifa, Israel., Saied L; Faculty of Biology, Technion-Israel Institute of Technology, Haifa, Israel., Ben-Yosef D; Faculty of Biology, Technion-Israel Institute of Technology, Haifa, Israel., Lavy T; Faculty of Biology, Technion-Israel Institute of Technology, Haifa, Israel., Kleifeld O; Faculty of Biology, Technion-Israel Institute of Technology, Haifa, Israel. Electronic address: okleifeld@technion.ac.il.

Publikováno v: Molecular & cellular proteomics : MCP [Mol Cell Proteomics] 2023 Jul; Vol. 22 (7), pp. 100584. Date of Electronic Publication: 2023 May 24.

Increasing the coverage of the N-terminome with LysN amino terminal enrichment (LATE).

Autor: Hanna R; Faculty of Biology, Technion-Israel Institute of Technology, Technion City, Haifa, Israel., Rozenberg A; Faculty of Biology, Technion-Israel Institute of Technology, Technion City, Haifa, Israel., Lavy T; Faculty of Biology, Technion-Israel Institute of Technology, Technion City, Haifa, Israel., Kleifeld O; Faculty of Biology, Technion-Israel Institute of Technology, Technion City, Haifa, Israel. Electronic address: okleifeld@technion.ac.il.

Publikováno v: Methods in enzymology [Methods Enzymol] 2023; Vol. 686, pp. 1-28. Date of Electronic Publication: 2023 May 18.

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