Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Lavinia Palamiuc"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2022)
While organelles are individual compartments with specialized functions, it is becoming clear that organellar communication is essential for maintaining cellular homeostasis. This cooperation is carried out by various interactions taking place on the
Externí odkaz:
https://doaj.org/article/202713ba9c994f08ad4a00da2ac920a2
Autor:
Lavinia Palamiuc, Tallie Noble, Emily Witham, Harkaranveer Ratanpal, Megan Vaughan, Supriya Srinivasan
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Serotonin is a potent stimulator of fat loss and energy expenditure in several species, includingC. elegans. Here, Palamiuc et al. identify the neuropeptide, FP-7, and its receptor in the intestine, NRP-22 as mediators of serotonergic body fat loss i
Externí odkaz:
https://doaj.org/article/6730459c83d44b3b82d15e60b1cc4677
Autor:
Lavinia Palamiuc, Anna Schlagowski, Shyuan T Ngo, Aurelia Vernay, Sylvie Dirrig‐Grosch, Alexandre Henriques, Anne‐Laurence Boutillier, Joffrey Zoll, Andoni Echaniz‐Laguna, Jean‐Philippe Loeffler, Frédérique René
Publikováno v:
EMBO Molecular Medicine, Vol 7, Iss 5, Pp 526-546 (2015)
Abstract Amyotrophic lateral sclerosis (ALS) is the most common fatal motor neuron disease in adults. Numerous studies indicate that ALS is a systemic disease that affects whole body physiology and metabolic homeostasis. Using a mouse model of the di
Externí odkaz:
https://doaj.org/article/41d9b19abb1b404ca75e031658be746d
Autor:
Yannick von Grabowiecki, Paula Abreu, Orphee Blanchard, Lavinia Palamiuc, Samir Benosman, Sophie Mériaux, Véronique Devignot, Isabelle Gross, Georg Mellitzer, José L Gonzalez de Aguilar, Christian Gaiddon
Publikováno v:
eLife, Vol 5 (2016)
Mechanisms of muscle atrophy are complex and their understanding might help finding therapeutic solutions for pathologies such as amyotrophic lateral sclerosis (ALS). We meta-analyzed transcriptomic experiments of muscles of ALS patients and mouse mo
Externí odkaz:
https://doaj.org/article/4b0325c5e8ea4d2baa0a5ac56259d422
Autor:
Ghulam Hussain, Florent Schmitt, Alexandre Henriques, Thiebault Lequeu, Frederique Rene, Françoise Bindler, Sylvie Dirrig-Grosch, Hugues Oudart, Lavinia Palamiuc, Marie-Helene Metz-Boutigue, Luc Dupuis, Eric Marchioni, Jose-Luis Gonzalez De Aguilar, Jean-Philippe Loeffler
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e64525 (2013)
The progressive deterioration of the neuromuscular axis is typically observed in degenerative conditions of the lower motor neurons, such as amyotrophic lateral sclerosis (ALS). Neurodegeneration in this disease is associated with systemic metabolic
Externí odkaz:
https://doaj.org/article/02d48fae28e6473693aef1fd013b64e0
Publikováno v:
Frontiers in Cell and Developmental Biology
While organelles are individual compartments with specialized functions, it is becoming clear that organellar communication is essential for maintaining cellular homeostasis. This cooperation is carried out by various interactions taking place on the
Autor:
Christian M. Metallo, Joanna Triscott, Ryan M. Loughran, Matthias Reist, Christof Fellmann, Brooke M. Emerling, Lavinia Palamiuc, Rachel J. Lew, Mark A. Rubin, Archna Ravi, Avi Kumar, Chantal Pauli, Vivian Tieu, Shauna L. Houlihan, Gurpreet K. Arora
Publikováno v:
Dev Cell
Summary PI5P4Ks are a class of phosphoinositide kinases that phosphorylate PI-5-P to PI-4,5-P2. Distinct localization of phosphoinositides is fundamental for a multitude of cellular functions. Here, we identify a role for peroxisomal PI-4,5-P2 genera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20feaabe2d446735479d086b4720e03b
https://doi.org/10.5167/uzh-204874
https://doi.org/10.5167/uzh-204874
Publikováno v:
FEBS J
Today, the importance of autophagy in physiological processes and pathological conditions is undeniable. Initially, autophagy merely was described as an evolutionarily conserved mechanism to maintain metabolic homeostasis in times of starvation; howe
Autor:
Brooke M. Emerling, Lavinia Palamiuc
Publikováno v:
The Journal of Experimental Medicine
Kaittanis et al. show that the processing of glutamated folates by prostate-specific membrane antigen induces the activation of metabotropic glutamate receptors and initiation of PI3K–Akt signaling in prostate cancer.
Prostate-specific membran
Prostate-specific membran
Autor:
Supriya Srinivasan, Lavinia Palamiuc, Harkaranveer Ratanpal, Tallie Noble, Megan Vaughan, Emily Witham
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Nature Communications
Nature Communications
Serotonin, a central neuromodulator with ancient ties to feeding and metabolism, is a major driver of body fat loss. However, mechanisms by which central serotonin action leads to fat loss remain unknown. Here, we report that the FLP-7 neuropeptide a