Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Lavinia Bisceglie"'
Autor:
Lavinia Bisceglie, Ann-Katrin Hopp, Kapila Gunasekera, Roni H. Wright, François Le Dily, Enrique Vidal, Alessandra Dall’Agnese, Luca Caputo, Chiara Nicoletti, Pier Lorenzo Puri, Miguel Beato, Michael O. Hottiger
Publikováno v:
iScience, Vol 24, Iss 5, Pp 102432- (2021)
Summary: While protein ADP-ribosylation was reported to regulate differentiation and dedifferentiation, it has so far not been studied during transdifferentiation. Here, we found that MyoD-induced transdifferentiation of fibroblasts to myoblasts prom
Externí odkaz:
https://doaj.org/article/7d19189afb6d4048bfbeb8b1940e2ea8
Autor:
Mario Leutert, Stephan Menzel, Rickmer Braren, Björn Rissiek, Ann-Katrin Hopp, Kathrin Nowak, Lavinia Bisceglie, Peter Gehrig, Hui Li, Anna Zolkiewska, Friedrich Koch-Nolte, Michael O. Hottiger
Publikováno v:
Cell Reports, Vol 24, Iss 7, Pp 1916-1929.e5 (2018)
Summary: The clostridium-like ecto-ADP-ribosyltransferase ARTC1 is expressed in a highly restricted manner in skeletal muscle and heart tissue. Although ARTC1 is well studied, the identification of ARTC1 targets in vivo and subsequent characterizatio
Externí odkaz:
https://doaj.org/article/2db6e3ed827944b1bbdbcac38feb4ed8
Autor:
Sarah Costantino, Przemyslaw Blyszczuk, Johan Auwerx, Melanie Greter, Anne Tailleux, Urs Eriksson, Julien Weber, Christian M. Matter, Simona Stivala, Sokrates Stein, Jürg H. Beer, Melroy X. Miranda, Bart Staels, Thomas F. Lüscher, Kathrin Nussbaum, Tasneem Arsiwala, Burkhard Becher, Francesco Paneni, Raul Mostoslavsky, Michael O. Hottiger, Lavinia Bisceglie, Lambertus J. van Tits, Daniel S. Gaul, Jürgen Pahla
Publikováno v:
Journal of Molecular and Cellular Cardiology. 139:24-32
Aims Sirtuin 6 (Sirt6) is a NAD+-dependent deacetylase that plays a key role in DNA repair, inflammation and lipid regulation. Sirt6-null mice show severe metabolic defects and accelerated aging. Macrophage-foam cell formation via scavenger receptors
Autor:
Luca Caputo, Alessandra Dall’Agnese, Enrique Vidal, Chiara Nicoletti, Roni H. G. Wright, Ann-Katrin Hopp, Michael O. Hottiger, Lavinia Bisceglie, Miguel Beato, Kapila Gunasekera, Pier Lorenzo Puri, François Le Dily
Publikováno v:
iScience, Vol 24, Iss 5, Pp 102432-(2021)
While protein ADP-ribosylation was reported to regulate differentiation and dedifferentiation, it has so far not been studied during transdifferentiation. Here, we found that MyoD-induced transdifferentiation of fibroblasts to myoblasts promotes the
Autor:
Ann-Katrin Hopp, Deena M. Leslie Pedrioli, Matthias Altmeyer, Kathrin Nowak, Kai Johnsson, Fabio Raith, Corentin Gondrand, Federico Teloni, Anna Howald, Michael O. Hottiger, Patrick G. A. Pedrioli, Lavinia Bisceglie, Lukas Muskalla
Publikováno v:
Molecular Cell
Molecular Cell, 81 (2)
Molecular Cell, 81 (2)
Summary In addition to its role as an electron transporter, mitochondrial nicotinamide adenine dinucleotide (NAD+) is an important co-factor for enzymatic reactions, including ADP-ribosylation. Although mitochondria harbor the most intra-cellular NAD
Protein ADP-ribosylation is a structurally heterogeneous post-translational modification (PTM) that influences the physicochemical and biological properties of the modified protein. ADP-ribosylation of chromatin changes its structural properties, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08c68d9d7ecae7207e16675a7ce34135
https://www.zora.uzh.ch/id/eprint/139248/
https://www.zora.uzh.ch/id/eprint/139248/
Autor:
Tiziana Santini, Chiara Pinnarò, Irene Bozzoni, Valentina Cazzella, Lavinia Bisceglie, Anna Tramontano, Mariangela Morlando, Daniel D'Andrea, Monica Ballarino, Andrea Cipriano, Luigi Grassi
Transcriptome analysis allowed the identification of new long noncoding RNAs differentially expressed during murine myoblast differentiation. These transcripts were classified on the basis of their expression under proliferating versus differentiated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae60bf7f10daf42ae8cecd22b55f412e
http://hdl.handle.net/11573/871673
http://hdl.handle.net/11573/871673