Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Lavinia A. Carabet"'
Autor:
Lavinia A. Carabet, Eric Leblanc, Nada Lallous, Helene Morin, Fariba Ghaidi, Joseph Lee, Paul S. Rennie, Artem Cherkasov
Publikováno v:
Molecules, Vol 24, Iss 4, p 763 (2019)
The heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) is a versatile RNA-binding protein playing a critical role in alternative pre-mRNA splicing regulation in cancer. Emerging data have implicated hnRNP A1 as a central player in a splicing regul
Externí odkaz:
https://doaj.org/article/80d2c9dafe284d928e46040c3a37af97
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 1, p 120 (2018)
Myc (avian myelocytomatosis viral oncogene homolog) represents one of the most sought after drug targets in cancer. Myc transcription factor is an essential regulator of cell growth, but in most cancers it is overexpressed and associated with treatme
Externí odkaz:
https://doaj.org/article/aec43810ad8f476893ad7aa89e5bdd5e
Autor:
Subha Madhavan, Yuriy Gusev, Michael Harris, David M. Tanenbaum, Robinder Gauba, Krithika Bhuvaneshwar, Andrew Shinohara, Kevin Rosso, Lavinia A. Carabet, Lei Song, Rebecca B. Riggins, Sivanesan Dakshanamurthy, Yue Wang, Stephen W. Byers, Robert Clarke, Louis M Weiner
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 13, Iss 9, Pp 771-783 (2011)
Currently, cancer therapy remains limited by a “one-size-fits-all” approach, whereby treatment decisions are based mainly on the clinical stage of disease, yet fail to reference the individual's underlying biology and its role driving malignancy.
Externí odkaz:
https://doaj.org/article/9045cc65f19b40ad849990fe620e1a2e
Publikováno v:
The Journal of Physical Chemistry B. 121:8706-8718
Many globins convert •NO to innocuous NO3– through their nitric oxide dioxygenase (NOD) activity. Mycobacterium tuberculosis fights the oxidative and nitrosative stress imposed by its host (the toxic effects of O2•– and •NO species and thei
Autor:
Paul S. Rennie, Sam Lawn, Eric Leblanc, Fariba Ghaidi, Ian G. Mills, Fuqiang Ban, Artem Cherkasov, Martin E. Gleave, Nada Lallous, Lavinia A. Carabet, Hélène Morin, Joseph Lee
Publikováno v:
Carabet, L A, Lallous, N, Leblanc, E, Ban, F, Morin, H, Lawn, S, Ghaidi, F, Lee, J, Mills, I G, Gleave, M E, Rennie, P S & Cherkasov, A 2018, ' Computer-aided drug discovery of Myc-Max inhibitors as potential therapeutics for prostate cancer ', European journal of medicinal chemistry, vol. 160, pp. 108-119 . https://doi.org/10.1016/j.ejmech.2018.09.023
While Myc is an essential regulator of growth in normal cells, it is also frequently associated with cancer progression, therapy-resistance and lethal outcomes in most human cancers. In prostate cancer (PCa), Myc transcription factors are implicated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fdac4bbea9bcb66582e024e18880f02
https://doi.org/10.1016/j.ejmech.2018.09.023
https://doi.org/10.1016/j.ejmech.2018.09.023
Autor:
Eric Leblanc, Nada Lallous, Fariba Ghaidi, Lavinia A. Carabet, Artem Cherkasov, Paul S. Rennie, Hélène Morin, Joseph Lee
Publikováno v:
Molecules
Molecules, 2019, Molecules (Basel, Switzerland), 24 (4), pp.763. ⟨10.3390/molecules24040763⟩
Volume 24
Issue 4
Molecules, Vol 24, Iss 4, p 763 (2019)
Molecules, 2019, Molecules (Basel, Switzerland), 24 (4), pp.763. ⟨10.3390/molecules24040763⟩
Volume 24
Issue 4
Molecules, Vol 24, Iss 4, p 763 (2019)
The heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) is a versatile RNA-binding protein playing a critical role in alternative pre-mRNA splicing regulation in cancer. Emerging data have implicated hnRNP A1 as a central player in a splicing regul
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 1, p 120 (2018)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Myc (avian myelocytomatosis viral oncogene homolog) represents one of the most sought after drug targets in cancer. Myc transcription factor is an essential regulator of cell growth, but in most cancers it is overexpressed and associated with treatme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82c58d371854eb420052492ffc84c09c
Autor:
Michael Harris, Yue Wang, David M. Tanenbaum, Yuriy Gusev, Krithika Bhuvaneshwar, Kevin Rosso, Andrew Shinohara, Stephen W. Byers, Robinder Gauba, Rebecca B. Riggins, Subha Madhavan, Lei Song, Lavinia A. Carabet, Sivanesan Dakshanamurthy, Louis M. Weiner, Robert Clarke
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 13, Iss 9, Pp 771-783 (2011)
Currently, cancer therapy remains limited by a “one-size-fits-all” approach, whereby treatment decisions are based mainly on the clinical stage of disease, yet fail to reference the individual's underlying biology and its role driving malignancy.
Autor:
Yue Wang, David M. Tanenbaum, Kevin Rosso, Lavinia A. Carabet, Robert Clarke, Robinder Gauba, Michael Harris, Stephen W. Byers, Andrew Shinohara, Yuriy Gusev, Sivanesan Dakshanamurthy, Krithika Bhuvaneshwar, Rebecca B. Riggins, Louis M. Weiner, Subha Madhavan, Lei Song
Publikováno v:
Genome Biology
The new and emerging field of systems medicine, an application of systems biology approaches to biomedical problems in the clinical setting, leverages complex computational tools and high dimensional data to derive personalized assessments of disease