Výsledky vyhledávání - "Lavinia, Balint"

Akademický článek

Mitochondrial DNA and Inflammation Are Associated with Cerebral Vessel Remodeling and Early Diabetic Kidney Disease in Patients with Type 2 Diabetes Mellitus

Autor: Ligia Petrica, Florica Gadalean, Danina Mirela Muntean, Dragos Catalin Jianu, Daliborca Vlad, Victor Dumitrascu, Flaviu Bob, Oana Milas, Anca Suteanu-Simulescu, Mihaela Glavan, Sorin Ursoniu, Lavinia Balint, Maria Mogos-Stefan, Silvia Ienciu, Octavian Marius Cretu, Roxana Popescu, Cristina Gluhovschi, Lavinia Iancu, Adrian Vlad

Publikováno v: Biomolecules, Vol 14, Iss 4, p 499 (2024)

Cerebrovascular disease accounts for major neurologic disabilities in patients with type 2 diabetes mellitus (DM). A potential association of mitochondrial DNA (mtDNA) and inflammation with cerebral vessel remodeling in patients with type 2 DM was ev

Externí odkaz: https://doaj.org/article/38db2f6927dd4e7fb84775199f135f7c

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Akademický článek

Metabolites Potentially Derived from Gut Microbiota Associated with Podocyte, Proximal Tubule, and Renal and Cerebrovascular Endothelial Damage in Early Diabetic Kidney Disease in T2DM Patients

Autor: Lavinia Balint, Carmen Socaciu, Andreea Iulia Socaciu, Adrian Vlad, Florica Gadalean, Flaviu Bob, Oana Milas, Octavian Marius Cretu, Anca Suteanu-Simulescu, Mihaela Glavan, Silvia Ienciu, Maria Mogos, Dragos Catalin Jianu, Sorin Ursoniu, Victor Dumitrascu, Daliborca Vlad, Roxana Popescu, Ligia Petrica

Publikováno v: Metabolites, Vol 13, Iss 8, p 893 (2023)

Complications due to type 2 diabetes mellitus (T2DM) such as diabetic kidney disease (DKD) and cerebral small vessel disease (CSVD) have a powerful impact on mortality and morbidity. Our current diagnostic markers have become outdated as T2DM-related

Externí odkaz: https://doaj.org/article/7bb69b8e5cf14126b3e6d8880a207456

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Akademický článek

Quantitative, Targeted Analysis of Gut Microbiota Derived Metabolites Provides Novel Biomarkers of Early Diabetic Kidney Disease in Type 2 Diabetes Mellitus Patients

Publikováno v: Biomolecules, Vol 13, Iss 7, p 1086 (2023)

Diabetic kidney disease (DKD) is one of the most debilitating complications of type 2 diabetes mellitus (T2DM), as it progresses silently to end-stage renal disease (ESRD). The discovery of novel biomarkers of early DKD becomes acute, as its incidenc

Externí odkaz: https://doaj.org/article/ba5b5505a82d495fadcae3164998ab8c

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Akademický článek

Metabolomic Investigation of Blood and Urinary Amino Acids and Derivatives in Patients with Type 2 Diabetes Mellitus and Early Diabetic Kidney Disease

Autor: Maria Mogos, Carmen Socaciu, Andreea Iulia Socaciu, Adrian Vlad, Florica Gadalean, Flaviu Bob, Oana Milas, Octavian Marius Cretu, Anca Suteanu-Simulescu, Mihaela Glavan, Silvia Ienciu, Lavinia Balint, Dragos Catalin Jianu, Ligia Petrica

Publikováno v: Biomedicines, Vol 11, Iss 6, p 1527 (2023)

Diabetic kidney disease (DKD) is the leading cause of end-stage renal disease; however, few biomarkers of its early identification are available. The aim of the study was to assess new biomarkers in the early stages of DKD in type 2 diabetes mellitus

Externí odkaz: https://doaj.org/article/aeb2c576791a4a81a6a04b133357544e

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Akademický článek

Untargeted Metabolomics by Ultra-High-Performance Liquid Chromatography Coupled with Electrospray Ionization-Quadrupole-Time of Flight-Mass Spectrometry Analysis Identifies a Specific Metabolomic Profile in Patients with Early Chronic Kidney Disease

Autor: Mihaela-Roxana Glavan, Carmen Socaciu, Andreea Iulia Socaciu, Florica Gadalean, Octavian M. Cretu, Adrian Vlad, Danina M. Muntean, Flaviu Bob, Oana Milas, Anca Suteanu, Dragos Catalin Jianu, Maria Stefan, Lavinia Balint, Silvia Ienciu, Ligia Petrica

Publikováno v: Biomedicines, Vol 11, Iss 4, p 1057 (2023)

Chronic kidney disease (CKD) has emerged as one of the most progressive diseases with increased mortality and morbidity. Metabolomics offers new insights into CKD pathogenesis and the discovery of new biomarkers for the early diagnosis of CKD. The ai

Externí odkaz: https://doaj.org/article/af50e5ec986d4731a4fe75e7c653c3b2

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Mitochondrial DNA Changes in Blood and Urine Display a Specific Signature in Relation to Inflammation in Normoalbuminuric Diabetic Kidney Disease in Type 2 Diabetes Mellitus Patients

Autor: Popescu, Ligia Petrica, Adrian Vlad, Florica Gadalean, Danina Mirela Muntean, Daliborca Vlad, Victor Dumitrascu, Flaviu Bob, Oana Milas, Anca Suteanu-Simulescu, Mihaela Glavan, Dragos Catalin Jianu, Sorin Ursoniu, Lavinia Balint, Maria Mogos-Stefan, Silvia Ienciu, Octavian Marius Cretu, Roxana

Publikováno v: International Journal of Molecular Sciences; Volume 24; Issue 12; Pages: 9803

Mitochondrial dysfunction is an important mechanism contributing to the development and progression of diabetic kidney disease (DKD). Mitochondrial DNA (mtDNA) levels in blood and urine were evaluated in relation to podocyte injury and proximal tubul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=multidiscipl::462c214d7b0924571243d63ce0e48cd6

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Metabolite Profiling of the Gut–Renal–Cerebral Axis Reveals a Particular Pattern in Early Diabetic Kidney Disease in T2DM Patients

Publikováno v: International Journal of Molecular Sciences; Volume 24; Issue 7; Pages: 6212

Type 2 diabetes mellitus (T2DM) represents an important microvascular disease concerning the kidney and the brain. Gut dysbiosis and microbiota-derived metabolites may be in relation with early pathophysiological changes in diabetic kidney disease (D

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99f27ab5e8af4f3a1288c7adc13607ea
https://doi.org/10.3390/ijms24076212

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Metabolomics in Chronic Kidney Diseases: Here to Stay

Autor: Lavinia Balint, Ligia Petrica, Silvia Ienciu, Danina Muntean, Dragos Catalin Jianu, Adrian Vlad, Florica Gadalean, Carmen Socaciu, Mihaela-Roxana Pătruică, Adrian Sturza

Publikováno v: Timisoara Medical Journal. 2020:1

Chronic kidney disease (CKD) affects around 13% of the adult population, has become a considerable concern worldwide, and is characterized by inadequate renal clearance, resulting in the accumulation of various potential toxic compounds. Metabolomics

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8b4b25d58e68f74e4a424839d5ca05e5
https://doi.org/10.35995/tmj20200208

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