Discrepancies in indel software resolution with somatic CRISPR/Cas9 tumorigenesis models.

Autor: Brockman QR; Department of Internal Medicine, Carver College of Medicine, University of Iowa, 375 Newton Rd, 5206 MERF, Iowa City, IA, 52246, USA.; Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA, USA., Scherer A; Department of Internal Medicine, Carver College of Medicine, University of Iowa, 375 Newton Rd, 5206 MERF, Iowa City, IA, 52246, USA., McGivney GR; Department of Internal Medicine, Carver College of Medicine, University of Iowa, 375 Newton Rd, 5206 MERF, Iowa City, IA, 52246, USA.; Cancer Biology Training Program, University of Iowa, Iowa City, IA, USA.; Department of Molecular Physiology and Biophysics, University of Iowa, Iowa City, IA, USA., Gutierrez WR; Department of Internal Medicine, Carver College of Medicine, University of Iowa, 375 Newton Rd, 5206 MERF, Iowa City, IA, 52246, USA.; Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA, USA.; Cancer Biology Training Program, University of Iowa, Iowa City, IA, USA.; Medical Scientist Training Program, University of Iowa, Iowa City, IA, USA., Rytlewski J; Department of Internal Medicine, Carver College of Medicine, University of Iowa, 375 Newton Rd, 5206 MERF, Iowa City, IA, 52246, USA., Sheehan A; Department of Internal Medicine, Carver College of Medicine, University of Iowa, 375 Newton Rd, 5206 MERF, Iowa City, IA, 52246, USA., Warrier A; Cancer Biology Training Program, University of Iowa, Iowa City, IA, USA.; Medical Scientist Training Program, University of Iowa, Iowa City, IA, USA., Laverty EA; Department of Internal Medicine, Carver College of Medicine, University of Iowa, 375 Newton Rd, 5206 MERF, Iowa City, IA, 52246, USA., Roughton G; Department of Internal Medicine, Carver College of Medicine, University of Iowa, 375 Newton Rd, 5206 MERF, Iowa City, IA, 52246, USA., Carnevale NC; Department of Internal Medicine, Carver College of Medicine, University of Iowa, 375 Newton Rd, 5206 MERF, Iowa City, IA, 52246, USA., Knepper-Adrian V; Department of Internal Medicine, Carver College of Medicine, University of Iowa, 375 Newton Rd, 5206 MERF, Iowa City, IA, 52246, USA., Dodd RD; Department of Internal Medicine, Carver College of Medicine, University of Iowa, 375 Newton Rd, 5206 MERF, Iowa City, IA, 52246, USA. rebecca-dodd@uiowa.edu.; Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA, USA. rebecca-dodd@uiowa.edu.; Cancer Biology Training Program, University of Iowa, Iowa City, IA, USA. rebecca-dodd@uiowa.edu.

Publikováno v: Scientific reports [Sci Rep] 2023 Sep 08; Vol. 13 (1), pp. 14798. Date of Electronic Publication: 2023 Sep 08.

PRC2 loss drives MPNST metastasis and matrix remodeling.

Autor: Brockman QR; Department of Internal Medicine.; Molecular Medicine Training Program., Scherer A; Department of Internal Medicine., McGivney GR; Department of Internal Medicine.; Cancer Biology Training Program.; Department of Molecular Physiology and Biophysics., Gutierrez WR; Department of Internal Medicine.; Cancer Biology Training Program.; Medical Scientist Training Program., Voigt AP; Molecular Medicine Training Program.; Medical Scientist Training Program.; Department of Ophthalmology and Visual Science., Isaacson AL; Department of Pathology., Laverty EA; Department of Internal Medicine., Roughton G; Department of Internal Medicine., Knepper-Adrian V; Department of Internal Medicine., Darbro B; Department of Pediatrics, and., Tanas MR; Department of Pathology., Stipp CS; Department of Molecular Physiology and Biophysics.; Department of Biology, University of Iowa, Iowa City, Iowa, USA., Dodd RD; Department of Internal Medicine.

Publikováno v: JCI insight [JCI Insight] 2022 Oct 24; Vol. 7 (20). Date of Electronic Publication: 2022 Oct 24.

Tumor Subtype Determines Therapeutic Response to Chimeric Polypeptide Nanoparticle-based Chemotherapy in Pten -deleted Mouse Models of Sarcoma.

Autor: Dodd RD; Department of Internal Medicine, University of Iowa, Iowa City, Iowa. rebecca-dodd@uiowa.edu david.kirsch@duke.edu., Scherer A; Department of Internal Medicine, University of Iowa, Iowa City, Iowa., Huang W; Department of Radiation Oncology, Duke University School of Medicine, Durham, North Carolina., McGivney GR; Department of Internal Medicine, University of Iowa, Iowa City, Iowa., Gutierrez WR; Department of Internal Medicine, University of Iowa, Iowa City, Iowa.; Medical Scientist Training Program, University of Iowa, Iowa City, Iowa., Laverty EA; Department of Internal Medicine, University of Iowa, Iowa City, Iowa., Ashcraft KA; Department of Radiation Oncology, Duke University School of Medicine, Durham, North Carolina., Stephens VR; Department of Internal Medicine, University of Iowa, Iowa City, Iowa., Yousefpour P; Department of Biomedical Engineering, Duke University, Durham, North Carolina., Saha S; Department of Biomedical Engineering, Duke University, Durham, North Carolina., Knepper-Adrian V; Department of Internal Medicine, University of Iowa, Iowa City, Iowa., Floyd W; Department of Radiation Oncology, Duke University School of Medicine, Durham, North Carolina.; Medical Scientist Training Program, Duke University School of Medicine, Durham, North Carolina., Chen M; Department of Radiation Oncology, Duke University School of Medicine, Durham, North Carolina.; Medical Scientist Training Program, Duke University School of Medicine, Durham, North Carolina., Ma Y; Department of Radiation Oncology, Duke University School of Medicine, Durham, North Carolina., Mastria EM; Department of Biomedical Engineering, Duke University, Durham, North Carolina.; Medical Scientist Training Program, Duke University School of Medicine, Durham, North Carolina., Cardona DM; Department of Pathology, Duke University School of Medicine, Durham, North Carolina., Eward WC; Department of Orthopedic Surgery, Duke University School of Medicine, Durham, North Carolina., Chilkoti A; Department of Biomedical Engineering, Duke University, Durham, North Carolina., Kirsch DG; Department of Radiation Oncology, Duke University School of Medicine, Durham, North Carolina. rebecca-dodd@uiowa.edu david.kirsch@duke.edu.; Department of Pharmacology & Cancer Biology, Duke University School of Medicine, Durham, North Carolina.

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2020 Sep 15; Vol. 26 (18), pp. 5036-5047. Date of Electronic Publication: 2020 Jul 27.