Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Laveniya, Satgunaseelan"'
Publikováno v:
Ophthalmology and Therapy, Vol 13, Iss 5, Pp 1399-1405 (2024)
Abstract Introduction This is a unique case report in medical literature for its detailing of diagnostics of an uncommon presentation of a rapid unexplained bilateral vision loss of a 73-year-old male diabetic patient. This report highlights the cruc
Externí odkaz:
https://doaj.org/article/c0d4fb21622c495384e500329a75cd79
Autor:
Laveniya Satgunaseelan, Maggie Lee, Sebastian Iannuzzi, Susannah Hallal, Kristine Deang, Kristian Stanceski, Heng Wei, Sofia Mason, Brindha Shivalingam, Hao-Wen Sim, Michael E. Buckland, Kimberley L. Alexander
Publikováno v:
Cancers, Vol 16, Iss 10, p 1906 (2024)
(1) Background: MGMT (O-6-methylguanine-DNA methyltransferase) promoter methylation remains an important predictive biomarker in high-grade gliomas (HGGs). The influence of necrosis on the fidelity of MGMT promoter (MGMTp) hypermethylation testing is
Externí odkaz:
https://doaj.org/article/695dbd433fa54826bac9ea8aad4ad39e
Autor:
Alexander Yuile, Laveniya Satgunaseelan, Joe Q. Wei, Michael Rodriguez, Michael Back, Nick Pavlakis, Amanda Hudson, Marina Kastelan, Helen R. Wheeler, Adrian Lee
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 7, Pp 5276-5292 (2023)
Genomic alterations of CDKN2A and CDKN2B in astrocytomas have been an evolving area of study for decades. Most recently, there has been considerable interest in the effect of CDKN2A and/or CDKN2B (CDKN2A/B) homozygous deletions (HD) on the prognosis
Externí odkaz:
https://doaj.org/article/cd5e480404154d849fb4a23f59390562
Autor:
Alexander Yuile, Laveniya Satgunaseelan, Joe Wei, Marina Kastelan, Michael F. Back, Maggie Lee, Heng Wei, Michael E. Buckland, Adrian Lee, Helen R. Wheeler
Publikováno v:
Current Issues in Molecular Biology, Vol 44, Iss 10, Pp 5117-5125 (2022)
Both IDH1 (isocitrate dehydrogenase 1) and IDH2 (isocitrate dehydrogenase 2) mutations play a vital role in the development of gliomas through disruption of normal cellular metabolic processes. Here we describe a case of a patient with an IDH-mutant
Externí odkaz:
https://doaj.org/article/c93322dca97a45f1b3d19a657c12c7a1
Autor:
Jason Saliba, Arpad Danos, Kilannin Krysiak, Adam Coffman, Susanna Kiwala, Joshua McMichael, Cameron Grisdale, Ian King, Shamini Selvarajah, Xinjie Xu, Rashmi Kanagal-Shamanna, Laveniya Satgunaseelan, David Meredith, Mark Evans, Charles Mullighan, Yassmine Akkari, Gordana Raca, Angshumoy Roy, Alex Wagner, Ramaswamy Govindan, Obi Griffith, Malachi Griffith
Publikováno v:
Genetics in Medicine Open, Vol 1, Iss 1, Pp 100098- (2023)
Externí odkaz:
https://doaj.org/article/24351fa03483446cb567a340e61249e1
Autor:
Takako Eva Yabe, Kylie King, Susan Russell, Laveniya Satgunaseelan, Ruta Gupta, James Chen, Bruce Ashford
Publikováno v:
Diagnostic Pathology, Vol 17, Iss 1, Pp 1-8 (2022)
Abstract Background The incidence of tongue cancer in young adults is on the rise. This trend is more pronounced in females. Although the aetiology is still unclear, there is mounting evidence that genetic syndromes can play a key role in development
Externí odkaz:
https://doaj.org/article/6b72b8ccc4b742edafeb10a1fff5dbe8
Autor:
Ágota Tűzesi, Susannah Hallal, Laveniya Satgunaseelan, Michael E. Buckland, Kimberley L. Alexander
Publikováno v:
Cancers, Vol 15, Iss 4, p 1232 (2023)
RNA modifications are diverse, dynamic, and reversible transcript alterations rapidly gaining attention due to their newly defined RNA regulatory roles in cellular pathways and pathogenic mechanisms. The exciting emerging field of ‘epitranscriptomi
Externí odkaz:
https://doaj.org/article/340055a298b84c798829f7f4cddb91b8
Autor:
Laveniya Satgunaseelan, Sean Porazinski, Dario Strbenac, Aji Istadi, Cali Willet, Tracy Chew, Rosemarie Sadsad, Carsten E. Palme, Jenny H. Lee, Michael Boyer, Jean Y. H. Yang, Jonathan R. Clark, Marina Pajic, Ruta Gupta
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
There is an increasing worldwide incidence of patients under 50 years of age presenting with oral squamous cell carcinoma (OSCC). The molecular mechanisms driving disease in this emerging cohort remain unclear, limiting impactful treatment options fo
Externí odkaz:
https://doaj.org/article/693a649c31a8476a9a20a57ba960f116
Autor:
Laveniya Satgunaseelan, Dario Strbenac, Sahithi Tadi, Kevin Nguyen, James Wykes, Carsten E. Palme, Tsu-Hui (Hubert) Low, Jean Y. H. Yang, Jonathan R. Clark, Ruta Gupta
Publikováno v:
Cancers, Vol 14, Iss 21, p 5213 (2022)
Viruses are well known drivers of several human malignancies. A causative factor for oral cavity squamous cell carcinoma (OSCC) in patients with limited exposure to traditional risk factors, including tobacco use, is yet to be identified. Our study a
Externí odkaz:
https://doaj.org/article/e17709b6ee0748d98f0d6e19497f74cb
Publikováno v:
Pathology. 55:551-554