Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Lavanya Adusumilli"'
Autor:
Swadhin Chandra Jana, Priya Dutta, Akanksha Jain, Anjusha Singh, Lavanya Adusumilli, Mukul Girotra, Diksha Kumari, Seema Shirolikar, Krishanu Ray
Publikováno v:
PLoS Genetics, Vol 20, Iss 5, p e1011305 (2024)
[This corrects the article DOI: 10.1371/journal.pgen.1009752.].
Externí odkaz:
https://doaj.org/article/efdfc8c006a74c6a80affbad02e0a231
Autor:
Swadhin Chandra Jana, Priya Dutta, Akanksha Jain, Anjusha Singh, Lavanya Adusumilli, Mukul Girotra, Diksha Kumari, Seema Shirolikar, Krishanu Ray
Publikováno v:
PLoS Genetics, Vol 17, Iss 8, p e1009752 (2021)
The cilium, the sensing centre for the cell, displays an extensive repertoire of receptors for various cell signalling processes. The dynamic nature of ciliary signalling indicates that the ciliary entry of receptors and associated proteins must be r
Externí odkaz:
https://doaj.org/article/7aa8f5ee7acb403eb8c75b91223fc765
Autor:
Lavanya Adusumilli, Nicola Facchinello, Cathleen Teh, Giorgia Busolin, Minh TN Le, Henry Yang, Giorgia Beffagna, Stefano Campanaro, Wai Leong Tam, Francesco Argenton, Bing Lim, Vladimir Korzh, Natascia Tiso
Publikováno v:
Cells, Vol 9, Iss 3, p 711 (2020)
During the development of the central nervous system, the proliferation of neural progenitors and differentiation of neurons and glia are tightly regulated by different transcription factors and signaling cascades, such as the Wnt and Shh pathways. T
Externí odkaz:
https://doaj.org/article/ab56c64bcad743c1bd56ad6e5c4d4762
Autor:
Jeffrey J. Jackson, Grant M. Shibuya, Buvana Ravishankar, Lavanya Adusumilli, Delia Bradford, Dirk G. Brockstedt, Cyril Bucher, Minna Bui, Cynthia Cho, Christoph Colas, Gene Cutler, Adrian Dukes, Xinping Han, Dennis X. Hu, Scott Jacobson, Paul D. Kassner, George E. Katibah, Michelle Yoo Min Ko, Urvi Kolhatkar, Paul R. Leger, Anqi Ma, Lisa Marshall, Jack Maung, Andrew A. Ng, Akinori Okano, Deepa Pookot, Daniel Poon, Chandru Ramana, Maureen K. Reilly, Omar Robles, Jacob B. Schwarz, Anton A. Shakhmin, Hunter P. Shunatona, Raashi Sreenivasan, Parcharee Tivitmahaisoon, Mengshu Xu, Thant Zaw, David J. Wustrow, Mikhail Zibinsky
Publikováno v:
Journal of Medicinal Chemistry. 65:12895-12924
General control nonderepressible 2 (GCN2) protein kinase is a cellular stress sensor within the tumor microenvironment (TME), whose signaling cascade has been proposed to contribute to immune escape in tumors. Herein, we report the discovery of cell-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11ef2aa8a880d39b628fb4a035cd9808
https://doi.org/10.1021/acs.jmedchem.2c00736
https://doi.org/10.1021/acs.jmedchem.2c00736
Autor:
Krishanu Ray, Anjusha Singh, Akanksha Jain, Priya Dutta, Seema Shirolikar, Lavanya Adusumilli, Mukul Girotra, Diksha Kumari, Swadhin Chandra Jana
Publikováno v:
PLoS Genetics, 17 (8)
PLoS Genetics
PLoS Genetics, Vol 17, Iss 8, p e1009752 (2021)
PLoS Genetics
PLoS Genetics, Vol 17, Iss 8, p e1009752 (2021)
The cilium, the sensing centre for the cell, displays an extensive repertoire of receptors for various cell signalling processes. The dynamic nature of ciliary signalling indicates that the ciliary entry of receptors and associated proteins must be r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c15af5840c5aec7d0cece40f7420f4a
https://hdl.handle.net/20.500.11850/502415
https://hdl.handle.net/20.500.11850/502415
Autor:
Francesco Argenton, Vladimir Korzh, Bing Lim, Cathleen Teh, Henry Yang, Minh T.N. Le, Wai Leong Tam, Giorgia Beffagna, Giorgia Busolin, Natascia Tiso, Lavanya Adusumilli, Nicola Facchinello, Stefano Campanaro
Publikováno v:
Cells
Volume 9
Issue 3
Cells, Vol 9, Iss 3, p 711 (2020)
Volume 9
Issue 3
Cells, Vol 9, Iss 3, p 711 (2020)
During the development of the central nervous system, the proliferation of neural progenitors and differentiation of neurons and glia are tightly regulated by different transcription factors and signaling cascades, such as the Wnt and Shh pathways. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5854377fd1a8e00af9fd1b12403f86d9
http://hdl.handle.net/11577/3331583
http://hdl.handle.net/11577/3331583
Autor:
Scott Jacobson, Jeffrey R. Jackson, Daniel Poon, Michelle Ko, Paul D. Kassner, Mikhail Zibinsky, Paul Leger, Heather Milestone, Deepika Kaveri, Anqi Ma, Thant Zaw, Lan Nguyen, Yamini M. Ohol, Tivitmahaisoon Parcharee, Chandru Ramana, Martin Brovarney, Delia Bradford, Cynthia Cho, Michael Sun, Lavanya Adusumilli, Jerick Sanchez, George E. Katibah, Omar Robles, Dan Nebalasca, Steve Wong, Blanca Gomez, Justy Gomez Guagua, Cyril Bucher, Rachel Ames, Mengshu Xu, David J. Wustrow, Anton Shakhmin, Andrew Ng, Dirk G. Brockstedt, Grant M. Shibuya, Molly Grandcolas
Publikováno v:
Cancer Research. 81:1646-1646
Hematopoietic progenitor kinase 1 (HPK1) is an intracellular protein kinase that negatively regulates T cell signaling and proliferation. Upon T cell receptor (TCR) activation, active HPK1 phosphorylates the adaptor protein SLP76 in the TCR complex,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::005f5043b3fbf76d7ae4770fdd4cc815
https://doi.org/10.1158/1538-7445.am2021-1646
https://doi.org/10.1158/1538-7445.am2021-1646
Autor:
George E. Katibah, Anqi Ma, Lisa Marshall, Thant Zaw, Andrew Ng, Deepa Pookot, M. Teresa Ciudad, Buvana Ravishankar, Justy Gomez Guagua, Paul D. Kassner, Tracy L. McGaha, Raashi Sreenivasan, Jeffrey R. Jackson, James E. Talmadge, Anton Shakhmin, Mengshu Xu, Urvi Kolhatkar, Dirk G. Brockstedt, Scott Jacobson, Lavanya Adusumilli, Grant M. Shibuya, Paul Leger, Mikhail Zibinsky, Holly C. Britton, Gene Cutler, David J. Wustrow, Delia Bradford, Omar Robles, Steve Wong, Chandru Ramana
Publikováno v:
Cancer Research. 81:3153-3153
Recent advances in cancer metabolism suggest that targeting amino acid metabolism represents a promising strategy for the development of novel therapeutic agents. Tumor, stromal and myeloid-derived suppressor cells (MDSC) within the tumor microenviro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d8ab0e96a60692045705ac6c38ccb50
https://doi.org/10.1158/1538-7445.am2021-3153
https://doi.org/10.1158/1538-7445.am2021-3153
Autor:
Buvana Ravishankar, Lavanya Adusumilli, Deepa Pookot Pookot, Emily Huang, Raashi Sreenivasan, Lisa Marshall, Deepika Kaveri, Oezcan Talay, Silpa Suthram, Svetlana Miakicheva, Abood Okal, Mikhail Zibinsky, Jeffrey Jackson, Grant Shibuya, Paul Leger, Parcharee Tivitmahaisoon, Scott Jacobson, Steve Wong, Angela Wadsworth, Jerick Sanchez, Martin Brovarney, David Chian, Sachie Marubayashi, Aparna Jorapur, Delia Bradford, Christophe Colas, Gene Cutler, Jacob Schwartz, David Wustrow, Paul Kassner, Dirk Brockstedt
Publikováno v:
Cancer Research. 79:1104-1104
The tumor microenvironment (TME) is characterized by deficiencies in oxygen and key nutrients, such as glucose and amino acids, resulting in an overall immune-suppressive environment. Key suppressive cell types in the TME include tumor, stromal and m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d03e198aa5e2aeba4468505e8d78367
https://doi.org/10.1158/1538-7445.am2019-1104
https://doi.org/10.1158/1538-7445.am2019-1104
Autor:
Nick Shah, Berenger Biannic, Andrea Kim, Scott Jacobson, Dennis X. Hu, Deepika Kaveri, Jack Maung, Gene Cutler, Betty Abraham, Jerick Sanchez, David J. Wustrow, Steve Wong, Jacob Bradley Schwarz, Akinori Okano, Paul Leger, Xinping Han, Michael Sun, Oezcan Talay, Paul D. Kassner, Delia Bradford, Cynthia Cho, Kyle Young, Deepa Pookot, Yamini M. Ohol, Nathan Kozon, Lavanya Adusumilli, Dirk G. Brockstedt, Payal Rana, Christophe Colas
Publikováno v:
Cancer Research. 79:4441-4441
USP7 is a deubiquitinase that regulates the levels of multiple downstream targets with roles in cancer progression and immune response. Inhibitors of USP7 may thus decrease oncogene function, increase tumor suppressor function, enhance immune functio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b89e097715cbdf88bc3ccb644ecd8fe
https://doi.org/10.1158/1538-7445.am2019-4441
https://doi.org/10.1158/1538-7445.am2019-4441