Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Lavannya Sabharwal"'
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 4 (2024)
ABSTRACTWe conducted a comparative evaluation of the FDA-cleared Simplexa GBS Direct and ARIES GBS molecular assays for the detection of Streptococcus agalactiae (Group B Streptococcus, GBS) in 386 prospectively collected, broth-enriched vaginal/rect
Externí odkaz:
https://doaj.org/article/11b17eb6b74e4b669b723a0d827ae835
Autor:
Paul Beinhoff, Lavannya Sabharwal, Vindhya Udhane, Cristina Maranto, Peter S. LaViolette, Kenneth M. Jacobsohn, Susan Tsai, Kenneth A. Iczkowski, Liang Wang, William A. Hall, Scott M. Dehm, Deepak Kilari, Marja T. Nevalainen
Publikováno v:
Cancers, Vol 13, Iss 20, p 5204 (2021)
Androgen deprivation therapy (ADT) for metastatic and high-risk prostate cancer (PC) inhibits growth pathways driven by the androgen receptor (AR). Over time, ADT leads to the emergence of lethal castrate-resistant PC (CRPC), which is consistently ca
Externí odkaz:
https://doaj.org/article/52440126acaa480b8e5b2dd4e3243b30
Autor:
Cristina Maranto, Vindhya Udhane, Jing Jia, Ranjit Verma, Gerhard Müller-Newen, Peter S. LaViolette, Michael Pereckas, Lavannya Sabharwal, Scott Terhune, Nagarajan Pattabiraman, Vincent C.O. Njar, John D. Imig, Liang Wang, Marja T. Nevalainen
Publikováno v:
Cancers, Vol 12, Iss 11, p 3412 (2020)
Stat5 is of significant interest in the search for new therapeutics for prostate cancer (PC) and hematopoietic disorders. We evaluated the transcriptomic specificity of the Stat5a/b inhibitor IST5-002 (IST5) in PC, defined more closely its mechanisms
Externí odkaz:
https://doaj.org/article/998515e9b75b47cb9289724ece3dfb49
Autor:
Yasunobu Arima, Daisuke Kamimura, Lavannya Sabharwal, Moe Yamada, Hidenori Bando, Hideki Ogura, Toru Atsumi, Masaaki Murakami
Publikováno v:
Mediators of Inflammation, Vol 2013 (2013)
The central nervous system (CNS) is an immune-privileged environment protected by the blood-brain barrier (BBB), which consists of specific endothelial cells that are brought together by tight junctions and tight liner sheets formed by pericytes and
Externí odkaz:
https://doaj.org/article/35d29310a64d4dfbbd84f0cd5a8350d1
Autor:
William A. Hall, Peter S. LaViolette, Lavannya Sabharwal, Kenneth Jacobsohn, Liang Wang, Kenneth A. Iczkowski, Scott M. Dehm, Vindhya Udhane, Marja T. Nevalainen, Cristina Maranto, Paul Beinhoff, Susan Tsai, Deepak Kilari
Publikováno v:
Cancers, Vol 13, Iss 5204, p 5204 (2021)
Cancers
Cancers
Simple Summary Prostate Cancer (PC) is currently estimated to affect 1 in 9 men and is the second leading cause of cancer in men in the US. While androgen deprivation therapy, which targets the androgen receptor, is one of the front-line therapies fo
Autor:
Masaru Ishii, Yasunobu Arima, Ikuma Nakagawa, Yuki Tanaka, Lavannya Sabharwal, Mitsutoshi Ota, Jing-Jing Jiang, Masaaki Murakami, Masayasu Okochi, Hideki Ogura, Daisuke Kamimura
Publikováno v:
The Journal of Immunology. 201:2256-2263
We recently reported that NF-κB–mediated inflammation caused by breakpoint cluster region (BCR) is dependent on the α subunit of casein kinase II (CK2α) complex. In the current study, we demonstrate that presenilin 1 (Psen1), which is a catalyti
Autor:
Lavannya Sabharwal, Scott S. Terhune, Gerhard Müller-Newen, Ranjit Verma, Vindhya Udhane, Liang Wang, John D. Imig, Michael Pereckas, Marja T. Nevalainen, Peter S. LaViolette, Jing Jia, Vincent C. O. Njar, Nagarajan Pattabiraman, Cristina Maranto
Publikováno v:
Cancers, Vol 12, Iss 3412, p 3412 (2020)
Cancers
Volume 12
Issue 11
Cancers 12(11), 3412 (2020). doi:10.3390/cancers12113412 special issue: "Special Issue "Cytokine and Steroid Hormone Signaling in Prostate Cancer" / Special Issue Editors: Prof. Marja T. Nevalainen, Prof. Scott Dehm, Prof. Dr. Vincent C. O. Njar"
Cancers
Volume 12
Issue 11
Cancers 12(11), 3412 (2020). doi:10.3390/cancers12113412 special issue: "Special Issue "Cytokine and Steroid Hormone Signaling in Prostate Cancer" / Special Issue Editors: Prof. Marja T. Nevalainen, Prof. Scott Dehm, Prof. Dr. Vincent C. O. Njar"
Stat5 is of significant interest in the search for new therapeutics for prostate cancer (PC) and hematopoietic disorders. We evaluated the transcriptomic specificity of the Stat5a/b inhibitor IST5-002 (IST5) in PC, defined more closely its mechanisms
Autor:
Masaaki Murakami, Daisuke Higo, Toru Atsumi, Ikuma Nakagawa, Yasunobu Arima, Osamu Nureki, Hideki Ogura, Hidenori Bando, Yuko Okuyama, Haruka Higuchi, Jie Meng, Mitsutoshi Ota, Daisuke Kamimura, Ryuichiro Ishitani, Lavannya Sabharwal, Momoko Okawara, Jing-Jing Jiang
Publikováno v:
The Journal of Immunology. 197:3111-3119
The breakpoint cluster region (BCR) is known as a kinase and cause of leukemia upon fusing to Abl kinase. In this study, we demonstrate that BCR associated with the α subunit of casein kinase II (CK2α), rather than BCR itself, is required for infla
Publikováno v:
Int J Biochem Cell Biol
A number of solid tumors are treated with radiation therapy (RT) as a curative modality. At the same time, for certain types of cancers the applicable doses of RT are not high enough to result in a successful eradication of cancer cells. This is ofte
Autor:
Jing-Jing Jiang, Masaaki Murakami, Naoki Nishikawa, Lavannya Sabharwal, Yasunobu Arima, Mineko Tsuruoka, Andrea Stofkova, Jie Meng, Hideki Ogura, Toru Atsumi, Hidenori Bando, Daisuke Kamimura, Kotaro Higuchi
Publikováno v:
International Immunology. 28:117-126
KDEL receptor 1 (KDELR1) regulates integrated stress responses (ISR) to promote naive T-cell survival in vivo . In a mouse line having nonfunctional KDELR1, T-Red (naive T-cell reduced) mice, polyclonal naive T cells show excessive ISR and eventually