What Is the Role of a Periarticular Injection for Knee Arthroplasty Patients Receiving a Multimodal Analgesia Regimen Incorporating Adductor Canal and Infiltration Between the Popliteal Artery and Capsule of the Knee Blocks? A Randomized Blinded Placebo-Controlled Noninferiority Trial.

Autor: YaDeau JT; From the Department of Anesthesiology, Critical Care and Pain Management, Hospital for Special Surgery, New York, New York.; Department of Anesthesiology, Weill Cornell Medicine, New York, New York., Cushner FD; Department of Orthopaedic Surgery (Adult Reconstruction and Joint Replacement Service), Hospital for Special Surgery, New York, New York., Westrich G; Department of Orthopaedic Surgery (Adult Reconstruction and Joint Replacement Service), Hospital for Special Surgery, New York, New York., Lauzadis J; From the Department of Anesthesiology, Critical Care and Pain Management, Hospital for Special Surgery, New York, New York., Kahn RL; From the Department of Anesthesiology, Critical Care and Pain Management, Hospital for Special Surgery, New York, New York.; Department of Anesthesiology, Weill Cornell Medicine, New York, New York., Lin Y; From the Department of Anesthesiology, Critical Care and Pain Management, Hospital for Special Surgery, New York, New York.; Department of Anesthesiology, Weill Cornell Medicine, New York, New York., Goytizolo EA; From the Department of Anesthesiology, Critical Care and Pain Management, Hospital for Special Surgery, New York, New York.; Department of Anesthesiology, Weill Cornell Medicine, New York, New York., Mayman DJ; Department of Orthopaedic Surgery (Adult Reconstruction and Joint Replacement Service), Hospital for Special Surgery, New York, New York., Jules-Elysee KM; From the Department of Anesthesiology, Critical Care and Pain Management, Hospital for Special Surgery, New York, New York.; Department of Anesthesiology, Weill Cornell Medicine, New York, New York., Gbaje E; From the Department of Anesthesiology, Critical Care and Pain Management, Hospital for Special Surgery, New York, New York., Padgett DE; Department of Orthopaedic Surgery (Adult Reconstruction and Joint Replacement Service), Hospital for Special Surgery, New York, New York.

Publikováno v: Anesthesia and analgesia [Anesth Analg] 2024 Jun 01; Vol. 138 (6), pp. 1163-1172. Date of Electronic Publication: 2024 Jan 08.

The Basic Science of Cannabinoids.

Autor: Sideris A; From the Department of Anesthesiology, Critical Care and Pain Medicine, Hospital for Special Surgery, New York, New York.; Department of Anesthesiology, Weill Cornell Medicine, New York, New York.; HSS Research Institute, New York, New York., Lauzadis J; From the Department of Anesthesiology, Critical Care and Pain Medicine, Hospital for Special Surgery, New York, New York., Kaczocha M; Department of Anesthesiology, Renaissance School of Medicine, Stony Brook University, Stony Brook, New York.

Publikováno v: Anesthesia and analgesia [Anesth Analg] 2024 Jan 01; Vol. 138 (1), pp. 42-53. Date of Electronic Publication: 2023 Dec 15.

Targeting intrinsically disordered regions facilitates discovery of calcium channels 3.2 inhibitory peptides for adeno-associated virus-mediated peripheral analgesia.

Autor: Shin SM; Department of Anesthesiology, Medical College of Wisconsin, Milwaukee, WI, United States., Lauzadis J; Department of Anesthesiology, Stony Brook University, Stony Brook, NY, United States., Itson-Zoske B; Department of Anesthesiology, Medical College of Wisconsin, Milwaukee, WI, United States., Cai Y; Department of Anesthesiology, Medical College of Wisconsin, Milwaukee, WI, United States.; Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, People's Republic of China., Fan F; Department of Pharmacology and Toxicology, The University of Mississippi Medical Center, Jackson, MS, United States., Natarajan GK; Department of Anesthesiology, Medical College of Wisconsin, Milwaukee, WI, United States., Kwok WM; Department of Anesthesiology, Medical College of Wisconsin, Milwaukee, WI, United States.; Department of Pharmacology and Toxicology, Medical College of Wisconsin, Milwaukee, WI, United States., Puopolo M; Department of Anesthesiology, Stony Brook University, Stony Brook, NY, United States., Hogan QH; Department of Anesthesiology, Medical College of Wisconsin, Milwaukee, WI, United States., Yu H; Department of Anesthesiology, Medical College of Wisconsin, Milwaukee, WI, United States.

Publikováno v: Pain [Pain] 2022 Dec 01; Vol. 163 (12), pp. 2466-2484. Date of Electronic Publication: 2022 Apr 14.

Anthrax toxins regulate pain signaling and can deliver molecular cargoes into ANTXR2 ⁺ DRG sensory neurons.

Autor: Yang NJ; Department of Immunology, Harvard Medical School, Boston, MA, USA., Isensee J; Translational Pain Research, Department of Anesthesiology and Intensive Care Medicine, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany., Neel DV; Department of Immunology, Harvard Medical School, Boston, MA, USA., Quadros AU; Center for Research in Inflammatory Diseases, Department of Pharmacology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil., Zhang HB; Department of Neurobiology, Harvard Medical School, Boston, MA, USA., Lauzadis J; Department of Anesthesiology, Stony Brook Medicine, Stony Brook, NY, USA., Liu SM; Ipsen Bioinnovation Ltd, Abingdon, UK., Shiers S; Department of Neuroscience, Center for Advanced Pain Studies, University of Texas at Dallas, Richardson, TX, USA., Belu A; Translational Pain Research, Department of Anesthesiology and Intensive Care Medicine, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany., Palan S; Ipsen Bioinnovation Ltd, Abingdon, UK., Marlin S; Ipsen Bioinnovation Ltd, Abingdon, UK., Maignel J; Ipsen Innovation, Les Ulis, France., Kennedy-Curran A; Department of Immunology, Harvard Medical School, Boston, MA, USA., Tong VS; Department of Immunology, Harvard Medical School, Boston, MA, USA., Moayeri M; Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Röderer P; Institute of Reconstructive Neurobiology, University of Bonn Medical Faculty and University Hospital Bonn, Bonn, Germany.; Cellomics Unit, LIFE & BRAIN GmbH, Bonn, Germany., Nitzsche A; Institute of Reconstructive Neurobiology, University of Bonn Medical Faculty and University Hospital Bonn, Bonn, Germany.; Cellomics Unit, LIFE & BRAIN GmbH, Bonn, Germany., Lu M; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, USA., Pentelute BL; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, USA.; The Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Center for Environmental Health Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA., Brüstle O; Institute of Reconstructive Neurobiology, University of Bonn Medical Faculty and University Hospital Bonn, Bonn, Germany., Tripathi V; Ipsen Bioinnovation Ltd, Abingdon, UK., Foster KA; Ipsen Bioinnovation Ltd, Abingdon, UK., Price TJ; Department of Neuroscience, Center for Advanced Pain Studies, University of Texas at Dallas, Richardson, TX, USA., Collier RJ; Department of Microbiology, Harvard Medical School, Boston, MA, USA., Leppla SH; Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Puopolo M; Department of Anesthesiology, Stony Brook Medicine, Stony Brook, NY, USA., Bean BP; Department of Neurobiology, Harvard Medical School, Boston, MA, USA., Cunha TM; Center for Research in Inflammatory Diseases, Department of Pharmacology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil., Hucho T; Translational Pain Research, Department of Anesthesiology and Intensive Care Medicine, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany., Chiu IM; Department of Immunology, Harvard Medical School, Boston, MA, USA. Isaac_Chiu@hms.harvard.edu.

Publikováno v: Nature neuroscience [Nat Neurosci] 2022 Feb; Vol. 25 (2), pp. 168-179. Date of Electronic Publication: 2021 Dec 20.

Contribution of T-Type Calcium Channels to Spinal Cord Injury-Induced Hyperexcitability of Nociceptors.

Autor: Lauzadis J; Graduate Program in Molecular and Cellular Pharmacology, Department of Pharmacology, Stony Brook Medicine, Stony Brook, NY 11794., Liu H; Department of Anesthesiology, HSC L4-076, Stony Brook Medicine, Stony Brook, NY 11794., Lu Y; Department of Anesthesiology, HSC L4-076, Stony Brook Medicine, Stony Brook, NY 11794., Rebecchi MJ; Department of Anesthesiology, HSC L4-076, Stony Brook Medicine, Stony Brook, NY 11794., Kaczocha M; Department of Anesthesiology, HSC L4-076, Stony Brook Medicine, Stony Brook, NY 11794., Puopolo M; Department of Anesthesiology, HSC L4-076, Stony Brook Medicine, Stony Brook, NY 11794 michelino.puopolo@stonybrook.edu.

Publikováno v: The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2020 Sep 16; Vol. 40 (38), pp. 7229-7240. Date of Electronic Publication: 2020 Aug 24.