Adaptation of the WHO guideline for residual DNA in parenteral vaccines produced on continuous cell lines to a limit for oral vaccines.

Autor: Lebron JA; Biologics Safety Assessment, 2 Acute Toxicology, Merck Research Laboratories, Merck & Co., Inc., West Point, Pennsylvania 19486, USA. Jose_lebron@merck.com, Troilol PJ, Pacchione S, Griffiths TG, Harper LB, Mixson LA, Jackson BE, Michna L, Barnum AB, Denisova L, Johnson CN, Maurer KL, Morgan-Hoffman S, Niu Z, Roden DF, Wang Z, Wolf JJ, Hamilton TR, Laux KM, Soper KA, Ledwith BJ

Publikováno v: Developments in biologicals [Dev Biol (Basel)] 2006; Vol. 123, pp. 35-44; discussion 55-73.