Amelioration of Alzheimer’s disease pathology by mitophagy inducers identified via machine learning and a cross-species workflow

Autor: Xie, Chenglong, Zhuang, Xu-Xu, Niu, Zhangming, Ai, Ruixue, Lautrup, Sofie Hindkjær, Zheng, Shuangjia, Jiang, Yinghui, Han, Ruiyu, Sengupta, Tanima, Cao, Shuqin, Lagartos-Donate, Maria Jose, Cai, Cui-Zan, Xie, Li-Ming, Caponio, Domenica, Wang, Wen-Wen, Schmauck-Medina, Tomás Alejandro, Zhang, Jianying, Wang, Heling, Lou, Guofeng, Xiao, Xianglu, Zheng, Wenhua, Palikaras, Konstantinos, Yang, Guang, Caldwell, Kim A., Caldwell, Guy A., Shen, Han-Ming, Nilsen, Hilde, Lu, Jia-Hong, Fang, Fei

Publikováno v: Xie, Chenglong Zhuang, Xu-Xu Niu, Zhangming Ai, Ruixue Lautrup, Sofie Hindkjær Zheng, Shuangjia Jiang, Yinghui Han, Ruiyu Sengupta, Tanima Cao, Shuqin Lagartos-Donate, Maria Jose Cai, Cui-Zan Xie, Li-Ming Caponio, Domenica Wang, Wen-Wen Schmauck-Medina, Tomás Alejandro Zhang, Jianying Wang, Heling Lou, Guofeng Xiao, Xianglu Zheng, Wenhua Palikaras, Konstantinos Yang, Guang Caldwell, Kim A. Caldwell, Guy A. Shen, Han-Ming Nilsen, Hilde Lu, Jia-Hong Fang, Fei . Amelioration of Alzheimer’s disease pathology by mitophagy inducers identified via machine learning and a cross-species workflow. Nature Biomedical Engineering. 2022, 6(1), 76-93
Nature Biomedical Engineering

Externí odkaz: http://hdl.handle.net/10852/99931

New hallmarks of ageing: a 2022 Copenhagen ageing meeting summary

Autor: Schmauck-Medina, Tomás Alejandro, Molière, Adrian, Lautrup, Sofie Hindkjær, Zhang, Jianying, Chlopicki, Stefan, Madsen, Helena Borland, Cao, Shuqin, Soendenbroe, Casper, Mansell, Els, Vestergaard, Mark Bitsch, Li, Zhiquan, Shiloh, Yosef, Opresko, Patricia L., Egly, Jean-Marc, Kirkwood, Thomas, Verdin, Eric, Bohr, Vilhelm A., Cox, Lynne S., Stevnsner, Tinna, Rasmussen, Lene Juel, Fang, Fei

Publikováno v: Schmauck-Medina, Tomás Alejandro Molière, Adrian Lautrup, Sofie Hindkjær Zhang, Jianying Chlopicki, Stefan Madsen, Helena Borland Cao, Shuqin Soendenbroe, Casper Mansell, Els Vestergaard, Mark Bitsch Li, Zhiquan Shiloh, Yosef Opresko, Patricia L. Egly, Jean-Marc Kirkwood, Thomas Verdin, Eric Bohr, Vilhelm A. Cox, Lynne S. Stevnsner, Tinna Rasmussen, Lene Juel Fang, Fei . New hallmarks of ageing: a 2022 Copenhagen ageing meeting summary. Aging. 2022, 14(16), 6829-6839
Aging

Externí odkaz: http://hdl.handle.net/10852/100170

Crosstalk among DNA Damage, Mitochondrial Dysfunction, Impaired Mitophagy, Stem Cell Attrition, and Senescence in the Accelerated Ageing Disorder Werner Syndrome

Autor: Gudmundsrud, Ruben, Skjånes, Tarjei Hartmann, Gilmour, Brian Christopher, Caponio, Domenica, Lautrup, Sofie Hindkjær, Fang, Fei

Publikováno v: Gudmundsrud, Ruben Skjånes, Tarjei Hartmann Gilmour, Brian Christopher Caponio, Domenica Lautrup, Sofie Hindkjær Fang, Fei . Crosstalk among DNA Damage, Mitochondrial Dysfunction, Impaired Mitophagy, Stem Cell Attrition, and Senescence in the Accelerated Ageing Disorder Werner Syndrome. Cytogenetic and Genome Research. 2021, 161(6-7), 297-304
Cytogenetic and Genome Research

Externí odkaz: http://hdl.handle.net/10852/93632
https://www.duo.uio.no/bitstream/handle/10852/93632/1/516386.pdf

Involvement of DNA repair in the preservation of cognitive preservation during aging and disease

Autor: Lautrup, Sofie Hindkjær

Publikováno v: Lautrup, S H 2018, Involvement of DNA repair in the preservation of cognitive preservation during aging and disease .

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pure_au_____::c1799d707b07b07e4961c70fc0c9aa11
https://pure.au.dk/portal/da/publications/involvement-of-dna-repair-in-the-preservation-of-cognitive-preservation-during-aging-and-disease(3d302556-f7b5-4ca6-93f8-a8a194062204).html

The NAD ⁺ -mitophagy axis in healthy longevity and in artificial intelligence-based clinical applications.

Autor: Aman Y; Department of Clinical Molecular Biology, University of Oslo and Akershus University Hospital, 1478, Lørenskog, Norway., Frank J; Department of Clinical Molecular Biology, University of Oslo and Akershus University Hospital, 1478, Lørenskog, Norway., Lautrup SH; Department of Clinical Molecular Biology, University of Oslo and Akershus University Hospital, 1478, Lørenskog, Norway., Matysek A; Department of Clinical Molecular Biology, University of Oslo and Akershus University Hospital, 1478, Lørenskog, Norway; School of Pharmacy and Division of Laboratory Medicine in Sosnowiec, Medical University of Silesia in Katowice, 40-055, Katowice, Poland., Niu Z; Aladdin Healthcare Technologies Ltd., 24-26 Baltic Street West, London, EC1Y OUR, UK., Yang G; Cardiovascular Research Centre, Royal Brompton Hospital, London, SW3 6NP, UK; National Heart and Lung Institute, Imperial College London, London, SW7 2AZ, UK., Shi L; Department of Psychiatry, University of Oxford, Oxford, UK., Bergersen LH; The Brain and Muscle Energy Group, Electron Microscopy Laboratory, Department of Oral Biology, University of Oslo, NO-0316, Oslo, Norway; Amino Acid Transporters, Division of Anatomy, Department of Molecular Medicine, Institute of Basic Medical Sciences (IMB) and Healthy Brain Ageing Centre (SERTA), University of Oslo, NO-0317, Oslo, Norway; Center for Healthy Aging, Department of Neuroscience and Pharmacology, Faculty of Health Sciences, University of Copenhagen, DK-2200, Copenhagen N, Denmark; The Norwegian Centre on Healthy Ageing (NO-Age), Oslo, Norway., Storm-Mathisen J; Amino Acid Transporters, Division of Anatomy, Department of Molecular Medicine, Institute of Basic Medical Sciences (IMB) and Healthy Brain Ageing Centre (SERTA), University of Oslo, NO-0317, Oslo, Norway; The Norwegian Centre on Healthy Ageing (NO-Age), Oslo, Norway., Rasmussen LJ; The Norwegian Centre on Healthy Ageing (NO-Age), Oslo, Norway; Center for Healthy Aging, Department of Cellular and Molecular Medicine, Faculty of Health Sciences, University of Copenhagen, DK-2200, Copenhagen N, Denmark., Bohr VA; Laboratory of Molecular Gerontology, National Institute on Aging, National Institutes of Health, Baltimore, MD, 21224, United States; The Norwegian Centre on Healthy Ageing (NO-Age), Oslo, Norway; Center for Healthy Aging, Department of Cellular and Molecular Medicine, Faculty of Health Sciences, University of Copenhagen, DK-2200, Copenhagen N, Denmark., Nilsen H; Department of Clinical Molecular Biology, University of Oslo and Akershus University Hospital, 1478, Lørenskog, Norway; The Norwegian Centre on Healthy Ageing (NO-Age), Oslo, Norway., Fang EF; Department of Clinical Molecular Biology, University of Oslo and Akershus University Hospital, 1478, Lørenskog, Norway; The Norwegian Centre on Healthy Ageing (NO-Age), Oslo, Norway. Electronic address: e.f.fang@medisin.uio.no.

Publikováno v: Mechanisms of ageing and development [Mech Ageing Dev] 2020 Jan; Vol. 185, pp. 111194. Date of Electronic Publication: 2019 Dec 05.