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Dietary Sugars Alter Hepatic Fatty Acid Oxidation via Transcriptional and Post-translational Modifications of Mitochondrial Proteins.

Autor: Softic S; Section on Integrative Physiology and Metabolism, Joslin Diabetes Center and Department of Medicine, Harvard Medical School, Boston, MA 02115, USA; Division of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Boston, MA 02115, USA; Division of Gastroenterology, Hepatology, Nutrition, Department of Pediatrics, University of Kentucky College of Medicine and Kentucky Children's Hospital, Lexington, KY 40506, USA. Electronic address: samir.softic@uky.edu., Meyer JG; Chemistry & Mass Spectrometry, Buck Institute for Research on Aging, Novato, CA 94945, USA., Wang GX; Section on Integrative Physiology and Metabolism, Joslin Diabetes Center and Department of Medicine, Harvard Medical School, Boston, MA 02115, USA., Gupta MK; Islet Cell and Regenerative Medicine, Joslin Diabetes Center and Department of Medicine, Harvard Medical School, Boston, MA 02115, USA., Batista TM; Section on Integrative Physiology and Metabolism, Joslin Diabetes Center and Department of Medicine, Harvard Medical School, Boston, MA 02115, USA., Lauritzen HPMM; Section on Integrative Physiology and Metabolism, Joslin Diabetes Center and Department of Medicine, Harvard Medical School, Boston, MA 02115, USA., Fujisaka S; Section on Integrative Physiology and Metabolism, Joslin Diabetes Center and Department of Medicine, Harvard Medical School, Boston, MA 02115, USA; First Department of Internal Medicine, University of Toyama, Toyama 930-0194, Japan., Serra D; School of Pharmacy, Institut de Biomedicina de la Universitat de Barcelona (IBUB), Universitat de Barcelona, Barcelona 08028, Spain; Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Instituto de Salud Carlos III, Madrid 28029, Spain., Herrero L; School of Pharmacy, Institut de Biomedicina de la Universitat de Barcelona (IBUB), Universitat de Barcelona, Barcelona 08028, Spain; Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Instituto de Salud Carlos III, Madrid 28029, Spain., Willoughby J; Alnylam Pharmaceuticals Inc., Cambridge, MA 021428, USA., Fitzgerald K; Alnylam Pharmaceuticals Inc., Cambridge, MA 021428, USA., Ilkayeva O; Sarah W. Stedman Nutrition and Metabolism Center and Duke Molecular Physiology Institute, Departments of Pharmacology & Cancer Biology and Medicine, Duke University Medical Center, Durham, NC 27701, USA., Newgard CB; Sarah W. Stedman Nutrition and Metabolism Center and Duke Molecular Physiology Institute, Departments of Pharmacology & Cancer Biology and Medicine, Duke University Medical Center, Durham, NC 27701, USA., Gibson BW; Chemistry & Mass Spectrometry, Buck Institute for Research on Aging, Novato, CA 94945, USA., Schilling B; Chemistry & Mass Spectrometry, Buck Institute for Research on Aging, Novato, CA 94945, USA., Cohen DE; Division of Gastroenterology and Hepatology, Weill Cornell Medical College New York, New York, NY 10021, USA., Kahn CR; Section on Integrative Physiology and Metabolism, Joslin Diabetes Center and Department of Medicine, Harvard Medical School, Boston, MA 02115, USA. Electronic address: c.ronald.kahn@joslin.harvard.edu.

Publikováno v: Cell metabolism [Cell Metab] 2019 Oct 01; Vol. 30 (4), pp. 735-753.e4.

Exercise Training Induces Depot-Specific Adaptations to White and Brown Adipose Tissue.

Autor: Lehnig AC; Department of Physiology and Cell Biology, Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University Wexner Medical Center, 460 W. 12(th) Avenue, Columbus, OH 43210, USA., Dewal RS; Department of Physiology and Cell Biology, Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University Wexner Medical Center, 460 W. 12(th) Avenue, Columbus, OH 43210, USA., Baer LA; Department of Physiology and Cell Biology, Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University Wexner Medical Center, 460 W. 12(th) Avenue, Columbus, OH 43210, USA., Kitching KM; Department of Physiology and Cell Biology, Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University Wexner Medical Center, 460 W. 12(th) Avenue, Columbus, OH 43210, USA., Munoz VR; Department of Physiology and Cell Biology, Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University Wexner Medical Center, 460 W. 12(th) Avenue, Columbus, OH 43210, USA; Laboratory of Molecular Biology of Exercise (LaBMEx), University of Campinas (UNICAMP), Limeira, São Paulo, Brazil., Arts PJ; Department of Physiology and Cell Biology, Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University Wexner Medical Center, 460 W. 12(th) Avenue, Columbus, OH 43210, USA., Sindeldecker DA; Department of Physiology and Cell Biology, Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University Wexner Medical Center, 460 W. 12(th) Avenue, Columbus, OH 43210, USA., May FJ; Department of Physiology and Cell Biology, Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University Wexner Medical Center, 460 W. 12(th) Avenue, Columbus, OH 43210, USA., Lauritzen HPMM; Section on Integrative Physiology and Metabolism, Joslin Diabetes Center, Boston, MA 02215, USA., Goodyear LJ; Section on Integrative Physiology and Metabolism, Joslin Diabetes Center, Boston, MA 02215, USA; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02215, USA., Stanford KI; Department of Physiology and Cell Biology, Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University Wexner Medical Center, 460 W. 12(th) Avenue, Columbus, OH 43210, USA. Electronic address: kristin.stanford@osumc.edu.

Publikováno v: IScience [iScience] 2019 Jan 25; Vol. 11, pp. 425-439. Date of Electronic Publication: 2019 Jan 03.