Noncoding mutations cause super-enhancer retargeting resulting in protein synthesis dysregulation during B cell lymphoma progression.

Autor: Leeman-Neill RJ; Department of Microbiology and Immunology, Vagelos College of Physicians and Surgeons, Columbia University, New York City, NY, USA.; Department of Pathology and Cell Biology, Vagelos College of Physicians and Surgeons, Columbia University, New York City, NY, USA., Song D; SIAT-HKUST Joint Laboratory of Cell Evolution and Digital Health, Shenzhen-Hong Kong Collaborative Innovation Research Institute, Shenzhen, China.; Division of Life Science, Department of Chemical and Biological Engineering, and State Key Laboratory of Molecular Neuroscience, The Hong Kong University of Science and Technology, Hong Kong SAR, China., Bizarro J; Department of Microbiology and Immunology, Vagelos College of Physicians and Surgeons, Columbia University, New York City, NY, USA., Wacheul L; RNA Molecular Biology, Fonds de la Recherche Scientifique (F.R.S./FNRS), Université libre de Bruxelles (ULB), Biopark Campus, Gosselies, Belgium., Rothschild G; Department of Microbiology and Immunology, Vagelos College of Physicians and Surgeons, Columbia University, New York City, NY, USA., Singh S; Institut für Medizinische Physik und Biophysik, Charité-Universitätsmedizin Berlin, Berlin, Germany., Yang Y; State Key Laboratory of Chemical Biology and Drug Discovery, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong SAR, China., Sarode AY; Department of Microbiology and Immunology, Vagelos College of Physicians and Surgeons, Columbia University, New York City, NY, USA., Gollapalli K; Department of Microbiology and Immunology, Vagelos College of Physicians and Surgeons, Columbia University, New York City, NY, USA., Wu L; Department of Microbiology and Immunology, Vagelos College of Physicians and Surgeons, Columbia University, New York City, NY, USA., Zhang W; Department of Microbiology and Immunology, Vagelos College of Physicians and Surgeons, Columbia University, New York City, NY, USA., Chen Y; Division of Life Science, Department of Chemical and Biological Engineering, and State Key Laboratory of Molecular Neuroscience, The Hong Kong University of Science and Technology, Hong Kong SAR, China., Lauring MC; Department of Microbiology and Immunology, Vagelos College of Physicians and Surgeons, Columbia University, New York City, NY, USA., Whisenant DE; Department of Microbiology and Immunology, Vagelos College of Physicians and Surgeons, Columbia University, New York City, NY, USA., Bhavsar S; Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Lim J; Department of Pharmacy, School of Pharmacy and Institute of New Drug Development, Jeonbuk National University, Jeonju, Republic of Korea., Swerdlow SH; Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Bhagat G; Department of Pathology and Cell Biology, Vagelos College of Physicians and Surgeons, Columbia University, New York City, NY, USA., Zhao Q; State Key Laboratory of Chemical Biology and Drug Discovery, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong SAR, China., Berchowitz LE; Department of Genetics and Development, Vagelos College of Physicians and Surgeons, Columbia University, New York City, NY, USA., Lafontaine DLJ; RNA Molecular Biology, Fonds de la Recherche Scientifique (F.R.S./FNRS), Université libre de Bruxelles (ULB), Biopark Campus, Gosselies, Belgium., Wang J; SIAT-HKUST Joint Laboratory of Cell Evolution and Digital Health, Shenzhen-Hong Kong Collaborative Innovation Research Institute, Shenzhen, China. jgwang@ust.hk.; Division of Life Science, Department of Chemical and Biological Engineering, and State Key Laboratory of Molecular Neuroscience, The Hong Kong University of Science and Technology, Hong Kong SAR, China. jgwang@ust.hk.; Hong Kong Center for Neurodegenerative Diseases, InnoHK, Hong Kong SAR, China. jgwang@ust.hk., Basu U; Department of Microbiology and Immunology, Vagelos College of Physicians and Surgeons, Columbia University, New York City, NY, USA. ub2121@cumc.columbia.edu.

Publikováno v: Nature genetics [Nat Genet] 2023 Dec; Vol. 55 (12), pp. 2160-2174. Date of Electronic Publication: 2023 Dec 04.

Characterising the long-term clinical outcomes of 1190 hospitalised patients with COVID-19 in New York City: a retrospective case series.

Autor: Shoucri SM; Medicine, Infectious Diseases, Columbia University Irving Medical Center, New York City, New York, USA sms2319@cumc.columbia.edu., Purpura L; Medicine, Infectious Diseases, Columbia University Irving Medical Center, New York City, New York, USA., DeLaurentis C; Medicine, Columbia University Irving Medical Center, New York City, New York, USA., Adan MA; Columbia University Vagelos College of Physicians and Surgeons, New York City, New York, USA., Theodore DA; Medicine, Infectious Diseases, Columbia University Irving Medical Center, New York City, New York, USA., Irace AL; Columbia University Vagelos College of Physicians and Surgeons, New York City, New York, USA., Robbins-Juarez SY; Columbia University Vagelos College of Physicians and Surgeons, New York City, New York, USA., Khedagi AM; Columbia University Vagelos College of Physicians and Surgeons, New York City, New York, USA., Letchford D; Columbia University Vagelos College of Physicians and Surgeons, New York City, New York, USA., Harb AA; Columbia University Vagelos College of Physicians and Surgeons, New York City, New York, USA., Zerihun LM; Columbia University Vagelos College of Physicians and Surgeons, New York City, New York, USA., Lee KE; Columbia University Vagelos College of Physicians and Surgeons, New York City, New York, USA., Gambina K; Columbia University Vagelos College of Physicians and Surgeons, New York City, New York, USA., Lauring MC; Columbia University Vagelos College of Physicians and Surgeons, New York City, New York, USA., Chen N; Columbia University Vagelos College of Physicians and Surgeons, New York City, New York, USA., Sperring CP; Columbia University Vagelos College of Physicians and Surgeons, New York City, New York, USA., Mehta SS; Columbia University Vagelos College of Physicians and Surgeons, New York City, New York, USA., Myers EL; Columbia University Vagelos College of Physicians and Surgeons, New York City, New York, USA., Shih H; Columbia University Vagelos College of Physicians and Surgeons, New York City, New York, USA., Argenziano MG; Columbia University Vagelos College of Physicians and Surgeons, New York City, New York, USA., Bruce SL; Columbia University Vagelos College of Physicians and Surgeons, New York City, New York, USA., Slater CL; Columbia University Vagelos College of Physicians and Surgeons, New York City, New York, USA., Tiao JR; Columbia University Vagelos College of Physicians and Surgeons, New York City, New York, USA., Natarajan K; Biomedical Informatics, Columbia University Irving Medical Center, New York City, New York, USA., Hripcsak G; Biomedical Informatics, Columbia University Irving Medical Center, New York City, New York, USA., Chen R; Biomedical Informatics, Columbia University Irving Medical Center, New York City, New York, USA.; Translational Data Science and Informatics, Geisinger, Danville, Pennsylvania, USA., Yin MT; Medicine, Infectious Diseases, Columbia University Irving Medical Center, New York City, New York, USA., Sobieszczyk ME; Medicine, Infectious Diseases, Columbia University Irving Medical Center, New York City, New York, USA., Castor D; Medicine, Infectious Diseases, Columbia University Irving Medical Center, New York City, New York, USA., Zucker JE; Medicine, Infectious Diseases, Columbia University Irving Medical Center, New York City, New York, USA.

Publikováno v: BMJ open [BMJ Open] 2021 Jun 02; Vol. 11 (6), pp. e049488. Date of Electronic Publication: 2021 Jun 02.