Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Laurina A. de Jong"'
Autor:
Robert C.A.M. van Waardenburg, Laurina A. de Jong, Foke van Delft, Maria A.J. van Eijndhoven, Melanie Bohlander, Mary-Ann Bjornsti, Jaap Brouwer, Jan H.M. Schellens
Publikováno v:
Molecular Cancer Therapeutics. 3:393-402
Phase I and II clinical trails are currently investigating the antitumor activity of cisplatin and camptothecins (CPTs; DNA topoisomerase I poisons), based on the dramatic synergistic cytotoxicity of these agents in some preclinical models. However,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a2717332a5cbb9d574ed797af5f2c70
https://doi.org/10.1158/1535-7163.393.3.4
https://doi.org/10.1158/1535-7163.393.3.4
Autor:
Paul J. Spiess, Christopher A. Klebanoff, Deborah R. Surman, Laurina A. de Jong, David M. Heimann, Florry A. Vyth-Dreese, Willem W. Overwijk, Zhiya Yu, Steven A. Rosenberg, Ada M. Kruisbeek, Steven E. Finkelstein, Douglas C. Palmer, Paul A. Antony, Leroy N. Hwang, Trees A. M. Dellemijn, Nicholas P. Restifo, Lionel Feigenbaum, Marc R. Theoret
Publikováno v:
The Journal of Experimental Medicine
Many tumor-associated antigens are derived from nonmutated “self” proteins. T cells infiltrating tumor deposits recognize self-antigens presented by tumor cells and can be expanded in vivo with vaccination. These T cells exist in a functionally t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f34cb4448545dd86e4841d79a173086
http://europepmc.org/articles/PMC2194177
http://europepmc.org/articles/PMC2194177
Autor:
Robert C.A.M. van Waardenburg, Maria A.J. van Eijndhoven, Lars E.T. Jansen, Caroline Verseyden, Mary-Ann Bjornsti, Dick Pluim, Jan H.M. Schellens, Laurina A. de Jong
Publikováno v:
The Journal of biological chemistry. 279(52)
Camptothecins constitute a novel class of chemotherapeutics that selectively target DNA topoisomerase I (Top1) by reversibly stabilizing a covalent enzyme-DNA intermediate. This cytotoxic mechanism contrasts with that of platinum drugs, such as cispl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aaf75ae5e67b926d5ae51c10103f016
https://pubmed.ncbi.nlm.nih.gov/15471886
https://pubmed.ncbi.nlm.nih.gov/15471886
Autor:
Robert C A M, van Waardenburg, Laurina A, de Jong, Foke, van Delft, Maria A J, van Eijndhoven, Melanie, Bohlander, Mary-Ann, Bjornsti, Jaap, Brouwer, Jan H M, Schellens
Publikováno v:
Molecular cancer therapeutics. 3(4)
Phase I and II clinical trails are currently investigating the antitumor activity of cisplatin and camptothecins (CPTs; DNA topoisomerase I poisons), based on the dramatic synergistic cytotoxicity of these agents in some preclinical models. However,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b7e852e2e7e29ed0499f4cbdd04a4915
https://pubmed.ncbi.nlm.nih.gov/15078982
https://pubmed.ncbi.nlm.nih.gov/15078982
Autor:
Jan H.M. Schellens, V. M. M. Herben, Robert C.A.M. van Waardenburg, Jos H. Beijnen, Dick Pluim, Laurina A. de Jong, Nadja E. Schoemaker, Wim W. ten Bokkel Huinink
Publikováno v:
Anti-cancer drugs. 13(1)
Topotecan stabilizes the topoisomerase I (Topo I) cleavable complex. We measured Topo I levels in white blood cells of patients with ovarian cancer treated with topotecan. Topotecan was given i.v. daily x 5 q 3 weeks in combination with paclitaxel (1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e25f6a5e40c86cde287e2f3b72c2731f
https://pubmed.ncbi.nlm.nih.gov/11914645
https://pubmed.ncbi.nlm.nih.gov/11914645
Autor:
Laurina A. de Jong, Corline J.A. De Groot, M.M. Schellekens, Catharina B.M. Maassen, Bert A. 't Hart, Jon D. Laman, Marjan van Meurs, Lizette Visser
Publikováno v:
Journal of Neuroimmunology, 119, 124-130. Elsevier
Experimental autoimmune encephalomyelitis (EAE) induced by immunization of mice with epitopes of the proteolipid protein (PLP), a major myelin constituent, forms a useful model for the study of multiple sclerosis (MS). In addition, MS patients displa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01ed0ac2b9116fb98efb2c94e45fd02b
https://pure.eur.nl/en/publications/cc1d15ff-406a-47ff-8ac0-83e5cce05fa3
https://pure.eur.nl/en/publications/cc1d15ff-406a-47ff-8ac0-83e5cce05fa3
