Výsledky vyhledávání - "Laurien Vancleef"

Akademický článek

The Gustatory Signaling Pathway and Bitter Taste Receptors Affect the Development of Obesity and Adipocyte Metabolism in Mice.

Autor: Bert Avau, Dries Bauters, Sandra Steensels, Laurien Vancleef, Jorien Laermans, Jens Lesuisse, Johan Buyse, H Roger Lijnen, Jan Tack, Inge Depoortere

Publikováno v: PLoS ONE, Vol 10, Iss 12, p e0145538 (2015)

Intestinal chemosensory signaling pathways involving the gustatory G-protein, gustducin, and bitter taste receptors (TAS2R) have been implicated in gut hormone release. Alterations in gut hormone profiles may contribute to the success of bariatric su

Externí odkaz: https://doaj.org/article/f7391bb13c5946a5bd104301eef260fa

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Akademický článek

Shifting the circadian rhythm of feeding in mice induces gastrointestinal, metabolic and immune alterations which are influenced by ghrelin and the core clock gene Bmal1.

Autor: Jorien Laermans, Charlotte Broers, Kelly Beckers, Laurien Vancleef, Sandra Steensels, Theo Thijs, Jan Tack, Inge Depoortere

Publikováno v: PLoS ONE, Vol 9, Iss 10, p e110176 (2014)

BackgroundIn our 24-hour society, an increasing number of people are required to be awake and active at night. As a result, the circadian rhythm of feeding is seriously compromised. To mimic this, we subjected mice to restricted feeding (RF), a parad

Externí odkaz: https://doaj.org/article/81638d7dd6634364a84ac3e9345e97b7

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The role of nutrient sensing in the metabolic changes after gastric bypass surgery

Autor: Laurien Vancleef, Jorien Laermans, Ricard Farré, Sandra Steensels, Matthias Lannoo, Kristin Verbeke, Bert Avau, Inge Depoortere

Taste receptors coupled to the gustatory G-protein, gustducin, on enteroendocrine cells sense nutrients to regulate gut hormone release. During Roux-en-Y gastric bypass (RYGB) surgery, the altered nutrient flow to more distal regions can affect gustd

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fef230a7eb29ad911e79d01e90e35e2
http://joe.endocrinology-journals.org/cgi/pmidlookup?view=long&pmid=27980002

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Attention allocation to ambiguous health/somatic threat cues

Autor: Laurien Vancleef, Johan W.S. Vlaeyen, Martien G.S. Schrooten

Publikováno v: European Journal of Pain. 19:1002-1011

Background An influential idea is that attentional bias to information related to pain or pain-related negative affect underlies persistent pain problems. Such information is however often ambiguous. If ambiguous input is perceived as pain or threat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bddf3ea0f271f461d158f234a42e87fb
https://doi.org/10.1002/ejp.628

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The Sweetener-Sensing Mechanisms of the Ghrelin Cell

Autor: Sandra Steensels, Laurien Vancleef, Inge Depoortere

Publikováno v: Nutrients, Vol 8, Iss 12, p 795 (2016)
Nutrients; Volume 8; Issue 12; Pages: 795
Nutrients

Carbohydrate administration decreases plasma levels of the 'hunger hormone' ghrelin. The ghrelin cell is co-localized with the sweet taste receptor subunit, TAS1R3, and the gustatory G-protein, gustducin, both involved in the sensing of sweeteners by

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6d18ec2eea7a8b478553e177bd89e04
http://www.mdpi.com/2072-6643/8/12/795

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Supplementation of oligofructose, but not sucralose, decreases high-fat diet induced body weight gain in mice independent of gustducin-mediated gut hormone release

Autor: Laurien Vancleef, Bert Avau, Ricard Farré, Kristin Verbeke, Inge Depoortere, Sandra Steensels, Leen Cools

Publikováno v: Molecular nutritionfood research. 61(3)

cope Entero-endocrine cells (EECs) sense nutrients through taste receptors similar to those on the tongue. Sweet -and fatty acid taste (FFAR) receptors coupled to the gustatory G-protein, gustducin, on EECs play a role in gut hormone release. We stud

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02f143c0b2bb198bf42e625e374df4f3
https://pubmed.ncbi.nlm.nih.gov/27800650

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Obesity Impairs Oligopeptide/Amino Acid-Induced Ghrelin Release and Smooth Muscle Contractions in the Human Proximal Stomach

Autor: Ricard Farré, Florence Baert, Laurien Vancleef, Anneleen Segers, Matthias Lannoo, Sandra Steensels, Jacques Pirenne, Inge Depoortere, Jan Tack, Laurens J. Ceulemans, Theo Thijs, Qiaoling Wang, Emilio Canovai

Publikováno v: Molecular Nutrition & Food Research. 62:1700804

Scope The satiation properties of proteins involve effects on gut peptide release and gastrointestinal motility which may be altered during obesity. This study compares the in vitro response and role of amino acid (AA) taste receptors (TASR) in the e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c60ea6812301bc538d3641945dc1efd
https://doi.org/10.1002/mnfr.201700804

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Role of the clock gene Bmal1 and the gastric ghrelin-secreting cell in the circadian regulation of the ghrelin-GOAT system

Autor: Laurien Vancleef, Inge Depoortere, Jorien Laermans, Jan Tack

Publikováno v: Scientific Reports

As adequate food intake is crucial to survival, organisms have evolved endogenous circadian clocks to generate optimal temporal patterns of food-related behavior and physiology. The gastric ghrelin-secreting cell is thought to be part of this network

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d1c74111a3ce66c2233a96619eac320
https://doi.org/10.1038/srep16748

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Chemosensory signalling pathways involved in sensing of amino acids by the ghrelin cell

Autor: Laurien Vancleef, Sandra Steensels, Theo Thijs, T. Van Den Broeck, Jan Tack, Inge Depoortere, Loïc Briand

Publikováno v: Scientific Reports
Scientific Reports, Nature Publishing Group, 2015, 5, pp.15725. ⟨10.1038/srep15725⟩
www.nature.com/scientificreports/
Scientific Reports (5), 15725. (2015)
Scientific Reports, Nature Publishing Group, 2015, 5, pp.15725. 〈10.1038/srep15725〉

Taste receptors on enteroendocrine cells sense nutrients and transmit signals that control gut hormone release. This study aimed to investigate the amino acid (AA) sensing mechanisms of the ghrelin cell in a gastric ghrelinoma cell line, tissue segme

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e38224b81c3b359c64b4b1844bf1af9

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