Výsledky vyhledávání - "Laurie W Leclair"

Transcriptional Changes in Chronic Rhinosinusitis with Asthma Favor a Type 2 Molecular Endotype Independent of Polyp Status [Corrigendum]

Autor: Amarbir S Gill, Abigail Pulsipher, Jorgen S Sumsion, Gretchen M Oakley, Laurie W Leclair, Heather Howe, Richard R Orlandi, Jeremiah A Alt

Publikováno v: Journal of Asthma and Allergy.

Gill AS, Pulsipher A, Sumsion JS, et al. J Asthma Allergy. 2021;14:405– 413 The authors have advised that they missed including a Funding statement in their paper. The following statement should have been included on page 412 of the published paper

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9aba62c733124ef81617da8a3b0b80da
https://www.dovepress.com/corrigendum-transcriptional-changes-in-chronic-rhinosinusitis-with-ast-peer-reviewed-fulltext-article-JAA

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Transcriptional Changes in Chronic Rhinosinusitis with Asthma Favor a Type 2 Molecular Endotype Independent of Polyp Status

Autor: Gretchen M. Oakley, Richard R. Orlandi, Abigail Pulsipher, Laurie W Leclair, Jeremiah A. Alt, Heather Howe, Amarbir S Gill, Jorgen S Sumsion

Publikováno v: Journal of Asthma and Allergy

Amarbir S Gill,1 Abigail Pulsipher,1 Jorgen S Sumsion,2 Gretchen M Oakley,1 Laurie W Leclair,3 Heather Howe,3 Richard R Orlandi,1 Jeremiah A Alt1 1Division of Otolaryngology – Head and Neck Surgery, Department of Surgery, University of Utah, Salt L

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcc667fd0a6cc43519fcbbf17ccc10c1
https://pubmed.ncbi.nlm.nih.gov/34140781

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Asthma increases long-term revision rates of endoscopic sinus surgery in chronic rhinosinusitis with and without nasal polyposis

Autor: Gretchen M. Oakley, Laurie W Leclair, Huong Meeks, Amarbir S Gill, Jeremiah A. Alt, Heather Howe, Kristine A. Smith, Karen Curtin, Richard R. Orlandi

Publikováno v: Int Forum Allergy Rhinol

BACKGROUND Chronic rhinosinusitis with asthma (CRS-A) has a significant impact on patient morbidity and quality of life. Nevertheless, little is known about the natural history of endoscopic sinus surgery (ESS) in this cohort. The objective of this s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86d58df7f5437f8ed1cf3706f5b2b797
https://pubmed.ncbi.nlm.nih.gov/33629540

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Twenty-Four-Hour Attending Coverage and Its Effect on Trainee Educational Opportunities

Autor: Laurie W Leclair, Kathryn N. Huggett, Jacqueline O’Toole, Renee D. Stapleton

Publikováno v: Medical Science Educator. 28:473-476

Nocturnal ICU staffing gained favor after correlation was shown between intensivist presence and better patient outcomes. We conducted a cross-sectional survey of stakeholders at a tertiary care academic medical center to evaluate the impact of 24-h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d2af7f3fde4e4aa420116899b677e0ff
https://doi.org/10.1007/s40670-018-0588-4

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Glutaredoxin-1 Attenuates S-Glutathionylation of the Death Receptor Fas and Decreases Resolution of Pseudomonas aeruginosa Pneumonia

Autor: Matthew J. Wargo, Laurie W Leclair, Scott W. Aesif, Yvonne M. W. Janssen-Heininger, Vikas Anathy, Sidra M. Hoffman, Karolyn G. Lahue, Amy S. Guala, Carlyne D. Cool, Jenna Bement, Benjamin T. Suratt

Publikováno v: American Journal of Respiratory and Critical Care Medicine. 189:463-474

The death receptor Fas is critical for bacterial clearance and survival of mice after Pseudomonas aeruginosa infection.Fas ligand (FasL)-induced apoptosis is augmented by S-glutathionylation of Fas (Fas-SSG), which can be reversed by glutaredoxin-1 (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7d278b6d2ed6756889507444219922f
https://doi.org/10.1164/rccm.201310-1905oc

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Bone Marrow‐Derived Mesenchymal Stromal Cells Inhibit Th2‐Mediated Allergic Airways Inflammation in Mice

Autor: Chad Steele, Nicholas P. Ziats, Daniel J. Weiss, Philip Eisenhauer, Matthew E. Poynter, Mercedes Rincon, Laurie W Leclair, Meagan Goodwin, Viranuj Sueblinvong

Publikováno v: STEM CELLS. 29:1137-1148

Bone marrow-derived mesenchymal stromal cells (BMSCs) mitigate inflammation in mouse models of acute lung injury. However, specific mechanisms of BMSC actions on CD4 T lymphocyte-mediated inflammation in vivo remain poorly understood. Limited data su

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8bf2a4b745fb9618fa6ee1e793d8d44
https://doi.org/10.1002/stem.656

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Mixed bacterial-fungal infections in the CF respiratory tract

Autor: Laurie W Leclair, Deborah A. Hogan

Publikováno v: Medical Mycology. 48:S125-S132

Cystic fibrosis (CF) is a common genetic disease whose major clinical manifestations include repeated episodes of airway infection and inflammation that ultimately result in premature death from respiratory failure. The consequences of infection by i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e0c9960eb0b73c7888c1c4fbdb60877
https://doi.org/10.3109/13693786.2010.521522

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Bioengineered Lysozyme Reduces Bacterial Burden and Inflammation in a Murine Model of Mucoid Pseudomonas aeruginosa Lung Infection

Autor: Charlotte C. Teneback, Laurie W Leclair, Thomas C. Scanlon, Matthew J. Wargo, Karl E. Griswold, Jenna Bement

The spread of drug-resistant bacterial pathogens is a growing global concern and has prompted an effort to explore potential adjuvant and alternative therapies derived from nature's repertoire of bactericidal proteins and peptides. In humans, the air

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::653ca50c0f2051124ee4007102066167
https://europepmc.org/articles/PMC3811238/

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Hemolytic Phospholipase C Inhibition Protects Lung Function during Pseudomonas aeruginosa Infection

Autor: Sathish Rajamani, Lennart K. A. Lundblad, Gilman B. Allen, Jenna L. Allard, Maegan J. Gross, Laurie W Leclair, Michael L. Vasil, Matthew J. Wargo, Deborah A. Hogan

The opportunistic pathogen Pseudomonas aeruginosa causes both acute and chronic lung infections and is particularly problematic in patients with cystic fibrosis and those undergoing mechanical ventilation. Decreased lung function contributes signific

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb38ef8332e6635863ba1d8d0ff0d477
https://europepmc.org/articles/PMC3175536/

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