Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Laurie S. Davis"'
Autor:
Amy M Becker, Kathryn H Dao, Bobby Kwanghoon Han, Roger Kornu, Shuchi Lakhanpal, Angela B Mobley, Quan-Zhen Li, Yun Lian, Tianfu Wu, Andreas M Reimold, Nancy J Olsen, David R Karp, Fatema Z Chowdhury, J David Farrar, Anne B Satterthwaite, Chandra Mohan, Peter E Lipsky, Edward K Wakeland, Laurie S Davis
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e67003 (2013)
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that is characterized by defective immune tolerance combined with immune cell hyperactivity resulting in the production of pathogenic autoantibodies. Previous gene expression studies
Externí odkaz:
https://doaj.org/article/fa7ba6fef3494bf898048d039e41f0e6
Autor:
Laurie S. Davis, Andreas M. Reimold
Publikováno v:
Rheumatology. 56:i100-i113
This review summarizes traditional and emerging therapies for SLE. Evidence suggests that the heterogeneity of SLE is a crucial aspect contributing to the failure of large clinical trials for new targeted therapies. A clearer understanding of the mec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d97ff513a9f11b7f70e50ea1a648aa1
https://doi.org/10.1093/rheumatology/kew417
https://doi.org/10.1093/rheumatology/kew417
Autor:
Laurie S. Davis, Andreas M. Reimold
Publikováno v:
Experimental and Therapeutic Medicine
Anti-nuclear antibodies (ANAs) may be induced in patients with rheumatoid arthritis (RA) receiving anti-tumor necrosis factor (TNF) therapy with TNF inhibitors (TNFi), etanercept, infliximab or adalimumab. In the present study, 11 patients who were T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a235ec12615caa2ab4a54a63b9179d8
https://doi.org/10.3892/etm.2017.4265
https://doi.org/10.3892/etm.2017.4265
Autor:
Teja Celhar, Anna-Marie Fairhurst, Anne B. Satterthwaite, Laurie S. Davis, Petra D. Cravens, Olga Zharkova
Publikováno v:
Rheumatology (Oxford, England)
SLE is a chronic autoimmune disease caused by perturbations of the immune system. The clinical presentation is heterogeneous, largely because of the multiple genetic and environmental factors that contribute to disease initiation and progression. Ove
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95e760ecaf18f1117d799ebb222395de
http://europepmc.org/articles/PMC5410978
http://europepmc.org/articles/PMC5410978
Autor:
Peter E. Lipsky, Sarah E Heuer, Matthew Ryals, Amrie C. Grammer, Rob D Robl, Michelle D. Catalina, Laurie S. Davis, Bernard Lauwerys, Sushma Madamanchi
Publikováno v:
Lupus. 25:1150-1170
Lupus patients are in need of modern drugs to treat specific manifestations of their disease effectively and safely. In the past half century, only one new treatment has been approved by the US Food and Drug Administration (FDA) for systemic lupus er
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2f29fa5898182587bccb2b41cd2f8a9
https://doi.org/10.1177/0961203316657437
https://doi.org/10.1177/0961203316657437
Autor:
Laurie S. Davis, Xiangmei Kong, Ann M. Stowe, Wendy I. White, Yue Wang, Nancy L. Monson, Ronald Herbst, Ding Chen, Sara J. Ireland
Publikováno v:
The Journal of Immunology. 196:1541-1549
The contribution of autoantibody-producing plasma cells in multiple sclerosis (MS) remains unclear. Anti-CD20 B cell depletion effectively reduces disease activity in MS patients, but it has a minimal effect on circulating autoantibodies and oligoclo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::458c76dc761806d8c9d8a6e22e65aa6e
https://doi.org/10.4049/jimmunol.1501376
https://doi.org/10.4049/jimmunol.1501376
Publikováno v:
Cytokine. 73:236-244
The cytokines IL-6 and IL-10 are produced by cells of the adaptive and innate arms of the immune system and they appear to play key roles in genetically diverse autoimmune diseases such as relapsing remitting multiple sclerosis (MS), rheumatoid arthr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82036b67b8dccb540aeb12b28d10c93c
https://doi.org/10.1016/j.cyto.2015.01.009
https://doi.org/10.1016/j.cyto.2015.01.009
Autor:
Laurie S. Davis
Publikováno v:
Arthritis & Rheumatology. 67:1147-1150
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88068b22490c2c0618cd21f3d5d99a1b
https://doi.org/10.1002/art.39052
https://doi.org/10.1002/art.39052
Autor:
Laurie S. Davis
Publikováno v:
Nature immunology
Cross-regulation of Toll-like receptor responses by cytokines is essential for effective host defense, avoidance of toxicity, and homeostasis, but the underlying mechanisms are not well understood. A comprehensive epigenomic approach in human macroph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1193a55f0f01b7a37b80726d59e27191
https://pubmed.ncbi.nlm.nih.gov/28825701
https://pubmed.ncbi.nlm.nih.gov/28825701
Autor:
Laurie S. Davis
Publikováno v:
Science Immunology. 2
A transancestral SLE study examining the relationship between genetic load and disease risk.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41e3555c6f0bc3f7ab89c3f12856a54d
https://doi.org/10.1126/sciimmunol.aao3114
https://doi.org/10.1126/sciimmunol.aao3114