Zobrazeno 1 - 10
of 203
pro vyhledávání: '"Laurie R, Goodrich"'
Autor:
Kyla F. Ortved, Larry Alward, Bobby Cowles, Renata Linardi, Dhvani Barot, Alex Usimaki, Joseph R. Fedie, Deb Amodie, Laurie R. Goodrich
Publikováno v:
Frontiers in Veterinary Science, Vol 11 (2024)
IntroductionAlpha 2 macroglobulin (A2M), a multi-functional protein in the plasma protease inhibitor class, regulates proinflammatory cytokines and the clearance of chondrodestructive enzymes in cases of joint injury and osteoarthritis (OA). The purp
Externí odkaz:
https://doaj.org/article/9a3a933dea9042be92ebf3e7fe17f8a6
Autor:
Lynn M. Pezzanite, Lyndah Chow, Gregg M. Griffenhagen, Luke Bass, Laurie R. Goodrich, Renata Impastato, Steven Dow
Publikováno v:
Frontiers in Veterinary Science, Vol 10 (2023)
IntroductionMultiple biological therapies for orthopedic injuries are marketed to veterinarians, despite a lack of rigorous comparative biological activity data to guide informed decisions in selecting a most effective compound. Therefore, the goal o
Externí odkaz:
https://doaj.org/article/7a211e234da24ac0b73c6659a9051314
Autor:
Parvathy Thampi, R. Jude Samulski, Joshua C. Grieger, Jennifer N. Phillips, C. Wayne McIlwraith, Laurie R. Goodrich
Publikováno v:
Frontiers in Veterinary Science, Vol 9 (2023)
Externí odkaz:
https://doaj.org/article/833bace64d6e4417b92cf39058342837
Autor:
Parvathy Thampi, R. Jude Samulski, Joshua C. Grieger, Jennifer N. Phillips, C. Wayne McIlwraith, Laurie R. Goodrich
Publikováno v:
Frontiers in Veterinary Science, Vol 9 (2022)
With an intrinsically low ability for self-repair, articular cartilage injuries often progress to cartilage loss and joint degeneration resulting in osteoarthritis (OA). Osteoarthritis and the associated articular cartilage changes can be debilitatin
Externí odkaz:
https://doaj.org/article/d56916efcfad4d71a6453d01888fc341
Orthobiologics in orthopedic applications: a report from the TMI Havemeyer meeting on orthobiologics
Autor:
Christian Lattermann, Chilan B.G. Leite, David D. Frisbie, Theodore S. Schlegel, Larry R. Bramlage, Thomas Koch, Christopher Centeno, Laurie R. Goodrich, Brian Johnstone, Rocci Trumper, Ashlee Watts, Christopher Little, Frank Barry, Farsh Guilak, C. Wayne McIlwraith
Publikováno v:
Journal of Cartilage & Joint Preservation, Vol 2, Iss 3, Pp 100055- (2022)
Readily available and effective therapeutic approaches are increasingly required to overcome the growing demand for optimized management of musculoskeletal degenerative conditions. The use of biologic therapies has been gaining ground in the orthoped
Externí odkaz:
https://doaj.org/article/a8f85c5b8fcd4d33be0f8938b705ef55
Autor:
Clodagh M. Kearney, Sohrab Khatab, Gerben M. van Buul, Saskia G. M. Plomp, Nicoline M. Korthagen, Margot C. Labberté, Laurie R. Goodrich, John D. Kisiday, P. R. Van Weeren, Gerjo J. V. M. van Osch, Pieter A. J. Brama
Publikováno v:
Frontiers in Veterinary Science, Vol 9 (2022)
BackgroundAllogenic mesenchymal stem cell (MSC) secretome is a novel intra-articular therapeutic that has shown promise in in vitro and small animal models and warrants further investigation.ObjectivesTo investigate if intra-articular allogenic MSC-s
Externí odkaz:
https://doaj.org/article/56e0347c945b41baa95ca7717ed69749
Publikováno v:
Journal of the American Veterinary Medical Association. :1-8
The use of radiofrequency energy (RFE) has become increasingly popular in equine orthopedic surgery in recent years, particularly for the debridement of cartilage lesions and soft tissue resection. However, despite considerable advancements in the te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1277b39d0209d9a5446101e4fa586b08
https://doi.org/10.2460/javma.23.01.0034
https://doi.org/10.2460/javma.23.01.0034
Autor:
Lynn Pezzanite, Lyndah Chow, Dean Hendrickson, Daniel L. Gustafson, A Russell Moore, Jason Stoneback, Gregg M. Griffenhagen, Gabriella Piquini, Jennifer Phillips, Paul Lunghofer, Steven Dow, Laurie R. Goodrich
Publikováno v:
Frontiers in Veterinary Science, Vol 8 (2021)
Septic arthritis causes significant morbidity and mortality in veterinary and human clinical practice and is increasingly complicated by multidrug-resistant infections. Intra-articular (IA) antibiotic administration achieves high local drug concentra
Externí odkaz:
https://doaj.org/article/366f5c5ee2e746f8a8cd009601488df1
Autor:
Lauren E. Smanik, Kurt T. Selberg, Gary L. Mason, Maria Brock, Holly L. Stewart, Laurie R. Goodrich, Christopher E. Kawcak
Publikováno v:
American Journal of Veterinary Research. :1-10
OBJECTIVE To perform a pilot study with the intent of assessing the feasibility of a modified subchondroplasty (mSCP) technique in a validated preclinical equine model of full-thickness articular cartilage loss and evaluate the short-term patient res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35682fc74c3eb979d068c86ece3e6817
https://doi.org/10.2460/ajvr.22.12.0219
https://doi.org/10.2460/ajvr.22.12.0219
Publikováno v:
Extracellular Vesicles and Circulating Nucleic Acids. 4:151-69
Osteoarthritis (OA) is a common joint disease affecting humans and horses, resulting in significant morbidity, financial expense, and loss of athletic use. While the pathogenesis is incompletely understood, inflammation is considered crucial in the d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::26f69923df21d2495aa68fa4305dddf0
https://doi.org/10.20517/evcna.2023.11
https://doi.org/10.20517/evcna.2023.11