Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Laurie Peverini"'
Publikováno v:
eLife, Vol 12 (2024)
The serotonin-gated ion channel (5-HT3R) mediates excitatory neuronal communication in the gut and the brain. It is the target for setrons, a class of competitive antagonists widely used as antiemetics, and is involved in several neurological disease
Externí odkaz:
https://doaj.org/article/eb93a186390641929cbf7efe09777ed3
Autor:
Sophie Shi, Solène N. Lefebvre, Laurie Peverini, Adrien H. Cerdan, Paula Milán Rodríguez, Marc Gielen, Jean-Pierre Changeux, Marco Cecchini, Pierre-Jean Corringer
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Glycine receptors are channel receptors mediating signal transduction between neurons that transit between resting and open states upon neurotransmitter binding. Here, the authors illuminate a progressive transition of opening by combining voltage-cl
Externí odkaz:
https://doaj.org/article/2f309521f60544c4a944d621a652fe13
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
The permeability of large cations through the P2X pore has remained arguably the most controversial and complicated topic in P2X-related research, with the emergence of conflicting studies on the existence, mechanism and physiological relevance of a
Externí odkaz:
https://doaj.org/article/072fd915a6e84948b417526f567e6acd
Autor:
Chloé Habermacher, Adeline Martz, Nicolas Calimet, Damien Lemoine, Laurie Peverini, Alexandre Specht, Marco Cecchini, Thomas Grutter
Publikováno v:
eLife, Vol 5 (2016)
P2X receptors function by opening a transmembrane pore in response to extracellular ATP. Recent crystal structures solved in apo and ATP-bound states revealed molecular motions of the extracellular domain following agonist binding. However, the mecha
Externí odkaz:
https://doaj.org/article/7aba456c03d5411892aaca6dec7080a0
Publikováno v:
Current Opinion in Pharmacology. 62:109-116
Ligand-gated ion channels (LGIC, also referred to as ionotropic receptors) are important transmembrane proteins that open to allow ions to flow across the membrane and locally modify the membrane potential in response to the binding of a ligand. For
Autor:
Adrien H. Cerdan, Laurie Peverini, Jean-Pierre Changeux, Pierre-Jean Corringer, Marco Cecchini
Publikováno v:
Science Advances
Science Advances, 2022, 8 (41), pp.eadc9340. ⟨10.1126/sciadv.adc9340⟩
Science Advances, Vol. 8, No. 41
Science Advances, 2022, 8 (41), pp.eadc9340. ⟨10.1126/sciadv.adc9340⟩
Science Advances, Vol. 8, No. 41
In-house VMD scripts for counting ion permeation events via the lateral/apical pathways over time and counting the number of chloride ions in the vestibule are provided at the following links: https://doi.org/10.5281/zenodo.6935496 and https://doi.or
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2510
P2X7 receptors are ATP-gated ion channels permeable to metal cations, such as Na
Autor:
Sophie Shi, Solène N Lefebvre, Laurie Peverini, Adrien Cerdan, Marc Gielen, Jean-Pierre Changeux, Marco Cecchini, Pierre-Jean Corringer
Pentameric ligand-gated ion channel mediate signal transduction at chemical synapses by transiting between resting and open states upon neurotransmitter binding. Here, we investigate the gating transition of the glycine receptor fluorescently labeled
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a400b2b883eef26baeb5b41d92c432bb
https://doi.org/10.1101/2022.06.04.494798
https://doi.org/10.1101/2022.06.04.494798
Publikováno v:
Methods in Molecular Biology ISBN: 9781071623831
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca5cb71d38cc6efa3a86f6bb1f96ab10
https://doi.org/10.1007/978-1-0716-2384-8_12
https://doi.org/10.1007/978-1-0716-2384-8_12
Publikováno v:
Frontiers in Molecular Neuroscience
Frontiers in Molecular Neuroscience, Frontiers Media, 2018, 11, ⟨10.3389/fnmol.2018.00265⟩
Frontiers in Molecular Neuroscience, Vol 11 (2018)
Frontiers in Molecular Neuroscience, Frontiers Media, 2018, 11, ⟨10.3389/fnmol.2018.00265⟩
Frontiers in Molecular Neuroscience, Vol 11 (2018)
The permeability of large cations through the P2X pore has remained arguably the most controversial and complicated topic in P2X-related research, with the emergence of conflicting studies on the existence, mechanism and physiological relevance of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddddd3007cc20df60e2e45e6974970a8
https://hal.archives-ouvertes.fr/hal-02404518
https://hal.archives-ouvertes.fr/hal-02404518