Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Laurie Minze"'
Autor:
Tuo Deng, Joey Liu, Yanru Deng, Laurie Minze, Xiang Xiao, Valerie Wright, Richeng Yu, Xian C. Li, Alecia Blaszczak, Stephen Bergin, David DiSilvestro, Ryan Judd, David Bradley, Michael Caligiuri, Christopher J. Lyon, Willa A. Hsueh
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Obesity is associated with inflammation in adipose tissue, characterized by a shift in local T cell subsets. Here the authors show that loss of MHCII expression on adipocytes increases levels of immunosuppressive regulatory T cells in adipose tissue,
Externí odkaz:
https://doaj.org/article/f06d437e5dce45deabca2a777dc8a491
Autor:
Jie Wu, Xiaomin Shi, Xiang Xiao, Laurie Minze, Jin Wang, Rafik M. Ghobrial, Jiahong Xia, Roger Sciammas, Xian C. Li, Wenhao Chen
Publikováno v:
The Journal of Immunology. 198:124.10-124.10
T cell dysfunction has emerged as a key event leading to failure in the control of persistent infections and tumors. However, the transcriptional determinants for T cell dysfunction remain unknown. Here we show that IRF4 is a key transcriptional dete
Autor:
Xiang Xiao, Xiaomin Shi, Yihui Fan, xiaolong zhang, minhao wu, wentao liu, Picheng Zhao, chenglin wu, Laurie Minze, Rafik Ghobrial, Xian Li
Publikováno v:
The Journal of Immunology. 194:134.13-134.13
Th17 cells produce copious amount of IL-17, which mediates host antimicrobial responses and autoimmune diseases. The exact mechanisms that control Th17 homeostasis, especially those that inhibit Th17 differentiation, remain incompletely defined. Here
Publikováno v:
The Journal of Immunology. 194:199.20-199.20
The signaling cascades triggered by OX40 in the control of diverse responses from initial T cell activation to the generation of memory and regulatory T cells remain incompletely defined. OX40 preferentially activates and sustains the non-canonical N