Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Laurie Maechler"'
Autor:
Amos B. Smith, Wenqing Yao, Laurie Maechler, Byron H. Arison, Avery Rosegay, Ralph Hirschmann, Paul A. Sprengeler
Publikováno v:
Tetrahedron Letters. 37:5637-5640
In an effort to cause significant conformational distortion and thereby possibly generate a pure SRIF antagonist, we undertook the synthesis of 2 , the first homodetic tricyclic peptide. This required five dimensional orthogonal amino protection and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b90194b791fecea64edfb67eeb39407
https://doi.org/10.1016/0040-4039(96)01221-x
https://doi.org/10.1016/0040-4039(96)01221-x
Autor:
J. Salvino, C. Donaldson, Kyriacos C. Nicolaou, S. Pietranico, E. M. Leahy, Catherine D. Strader, Paul A. Sprengeler, George T. Furst, Ralph Hirschmann, Margaret A. Cascieri, Laurie Maechler, A. B. Iii Smith, W. Vale, Mari R. Candelore
Publikováno v:
ChemInform. 24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f54503e75eec3fa69ec38e717f0ef3e9
https://doi.org/10.1002/chin.199308266
https://doi.org/10.1002/chin.199308266
Publikováno v:
Neuron. 8:59-70
Type IIA rat brain Na + channel a subunits were expressed in CHO cells by nuclear microinjection or by transfection using a vector containing both metallothionein and bacteriophage SP6 promoters. Stable cell lines expressing Na + channels were isolat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53f0d8add062e24d0f8ac6b60d1b9018
https://doi.org/10.1016/0896-6273(92)90108-p
https://doi.org/10.1016/0896-6273(92)90108-p
Autor:
Rachel D. van Rijn, and Paul A. Sprengeler, Ralph Hirschmann, Laurie Maechler, † Maria A. Cichy-Knight, Margaret A. Cascieri, John Hynes, Wenqing Yao, Catherine D. Strader, Amos B. Smith
Publikováno v:
Journal of medicinal chemistry. 39(13)
The endogenous peptides somatostatin (SRIF) and substance P comprise very different structures. Although both bind G-protein-coupled receptors, the SRIF receptors (SSTR 1-5) recognize SRIF and related peptides which retain its beta-turn such as the p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1e133729dc9a86c6e0c7809db12328e
https://pubmed.ncbi.nlm.nih.gov/8691440
https://pubmed.ncbi.nlm.nih.gov/8691440
Autor:
Laurie Maechler, W. Vale, C. D. Strader, George T. Furst, J. Salvino, Mari R. Candelore, Amos B. Smith, M. A. Cascieri, Paul A. Sprengeler, S. Pietranico, C. Donaldson, E. M. Leahy, Ralph Hirschmann, Kyriacos C. Nicolaou
Publikováno v:
Journal of the American Chemical Society. 114:9217-9218
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c1a5c6f302e85c2565c407757cad49f1
https://doi.org/10.1021/ja00049a081
https://doi.org/10.1021/ja00049a081