Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Laurie Gauthier"'
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
The respiratory mucosa is the primary portal of entry for numerous viruses such as the respiratory syncytial virus, the influenza virus and the parainfluenza virus. These pathogens initially infect the upper respiratory tract and then reach the lower
Externí odkaz:
https://doaj.org/article/05554df2d45b4021ab0433852488ea3c
Autor:
Félix Lamontagne, Dominic Arpin, Mélanie Côté‐Cyr, Vinay Khatri, Philippe St‐Louis, Laurie Gauthier, Denis Archambault, Steve Bourgault
Publikováno v:
Advanced Healthcare Materials.
Publikováno v:
ACS biomaterials scienceengineering. 8(2)
Proteinaceous nanoparticles represent attractive antigen carriers for vaccination as their size and repetitive antigen displays that mimic most viral particles enable efficient immune processing. However, these nanocarriers are often unable to stimul
Publikováno v:
Vaccine. 40(1)
Flagellin constitutes a potential adjuvant for vaccines owing to its robust immunostimulatory properties. However, clinical trials have revealed that flagellin derived from Salmonella enterica serovar Typhimurium induces high levels of proinflammator
Autor:
Laurie Gauthier, Élise Duchesne, Laurie Pouliot, Émilie McNicoll, Claudia Lavoie, Marie-Michèle Fiset, Cynthia Gagnon, Marie-Pier Roussel
Publikováno v:
Journal of neurology. 268(11)
Myotonic dystrophy type 1 (DM1) is a progressive, multisystemic, and autosomal dominant disease. Muscle wasting and weakness have been associated with impaired functional capacity and restricted social participation in affected individuals. The disea
Publikováno v:
Immunobiology. 225(4)
By modulating specific immune responses against antigens, adjuvants are used in many vaccine preparations to enhance protective immunity. The C-terminal domain of the protein P97 (P97c) of Mycoplasma hyopneumoniae, which is the etiologic agent of por
Autor:
Laurie Gauthier, Steve Bourgault, Margaryta Babych, Jessica Dion, Geneviève Bertheau-Mailhot, Ximena Zottig, Denis Archambault
Publikováno v:
Nanoscale. 10:19547-19556
The design of nanoparticles exposing a high density of antigens constitutes a promising strategy to address safety concerns of conventional life-attenuated vaccines as well as to increase the immunogenicity of subunit vaccines. In this study, we deve