Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Laurie E. Lambert"'
Autor:
Jennifer S. Berling, E Choi, Gail A. Bishop, Laurie E. Lambert, Jonathan A. Harton, Susan D. Thompson
Publikováno v:
Cellular Immunology. 165:202-210
T cells play a critical role in the development of collagen-induced arthritis (CIA). Immunization with heterologous (chick) type II collagen (cII) results in chronic inflammation with progressive damage to the joints. The expression of specific MHC C
Publikováno v:
European Journal of Pharmacology. 216:131-134
We have assessed the capacity of two novel inhibitors to block cytokine-induced nitric oxide (NO) synthesis by macrophages and vascular smooth muscle cells, as well as NO production by the constitutive enzyme in central nervous system tissue. NG-Cycl
Publikováno v:
Cellular immunology. 162(2)
The expression of specific alleles of the human HLA-DR locus is associated with increased risk for the development of rheumatoid arthritis. Examination of the amine acid sequence of the DR β chain has revealed that risk for RA correlates with a clus
Publikováno v:
Immunopharmacology. 29(2)
The S-adenosyl-L-homocysteine (AdoHcy) hydrolase inhibitor MDL 28,842 has been demonstrated to be a potent inhibitor of T-cell activation, both in vitro and in vivo. Although the inhibition of T cells in vitro was independent of macrophages, the dire
Autor:
Jennifer S. Berling, Laurie E. Lambert
Publikováno v:
Cellular immunology. 153(1)
T lymphocytes play a critical role in the development of murine collagen-induced arthritis (CIA), a syndrome which shares many features with rheumatoid arthritis. In susceptible mouse strains, immunization with type II collagen (cII) results in chron
Autor:
Bruce M. Baron, Ian A. McDonald, Hsien C. Cheng, Laurie E. Lambert, Jeffrey P. Whitten, Niall S. Doherty
Publikováno v:
Life sciences. 48(1)
Inhibition of nitric oxide production by arginine analogues was examined in three cell systems; macrophages, CNS tissue and endothelial cells. Nitric oxide production was assessed indirectly using in vitro assays measuring nitrite production (macroph
Autor:
Masayuki Mano, George Ku, Jeffrey P. Whitten, Laurie E. Lambert, Mao Simon J T, Ian A. McDonald, Mark T. Yates
Publikováno v:
FEBS Letters. (2):135-138
Low density lipoproteins (LDL) oxidatively modified by macrophages have been shown to be atherogenic in ex vivo studies. We studied the potential role of nitric oxide (NO), a free radical produced by macrophages, in LDL modification. Human LDL (1 mg/
Autor:
Donna M. Paulnock, Laurie E. Lambert
Publikováno v:
Cellular immunology. 120(2)
Macrophage cell lines were used in these studies as a model system to dissect the biochemical and functional mosaic of the macrophage activation process. In particular, the requirements for the induction of tumoricidal and bactericidal activity in th