Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Laurie E. Comstock"'
Autor:
Hunter L. Abrahamsen, Tristan C. Sanford, Casie E. Collamore, Bronte A. Johnstone, Michael J. Coyne, Leonor García-Bayona, Michelle P. Christie, Jordan C. Evans, Allison J. Farrand, Katia Flores, Craig J. Morton, Michael W. Parker, Laurie E. Comstock, Rodney K. Tweten
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Cholesterol-dependent cytolysins (CDCs) comprise a large family of pore-forming toxins produced by Gram-positive bacteria, which are used to attack eukaryotic cells. Here, we functionally characterize a family of 2-component CDC-like (CDCL)
Externí odkaz:
https://doaj.org/article/fa81631103bf486aa966a456bbef1768
Autor:
Jordan C. Evans, Valentina Laclare McEneany, Michael J. Coyne, Elizabeth P. Caldwell, Madeline L. Sheahan, Salena S. Von, Emily M. Coyne, Rodney K. Tweten, Laurie E. Comstock
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
The bacterium Phocaeicola vulgatus is commonly found in the human gut. Here, the authors show that the microorganism produces an antibacterial toxin that targets the LPS core glycan of closely related species and induces a response that partially pro
Externí odkaz:
https://doaj.org/article/69744958344440f3b702e995fc9d50c8
Autor:
William P. J. Smith, Maj Brodmann, Daniel Unterweger, Yohan Davit, Laurie E. Comstock, Marek Basler, Kevin R. Foster
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Game theory has contributed much to the understanding of social evolution. In an elegant combination of experimental tests and modelling, this study suggests that when bacteria face intense competition, repeated retaliation outcompetes a single tit-f
Externí odkaz:
https://doaj.org/article/417be2c582b24ce690e6e37998fef6ac
Publikováno v:
mBio, Vol 12, Iss 5 (2021)
The bacteroidetocins are a newly discovered class of bacteriocins specific to BacteroidetesBacteroidesParabacteroidesPrevotellaPrevotella
Externí odkaz:
https://doaj.org/article/8c7f9e2310e541e7a29f7d367ab3458c
Autor:
Michael J. Coyne, Nathalie Béchon, Leigh M. Matano, Valentina Laclare McEneany, Maria Chatzidaki-Livanis, Laurie E. Comstock
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Bacteria often produce antimicrobial toxins to compete in microbial communities. Here, the authors identify a family of peptide toxins that are produced by, and target, Bacteroidetes species, some of which are widespread in the human gut microbiota.
Externí odkaz:
https://doaj.org/article/78585f72ad1d430db474577156b7fd5b
Autor:
Takeshi Ito, Rene Gallegos, Leigh M. Matano, Nicole L. Butler, Noam Hantman, Matthew Kaili, Michael J. Coyne, Laurie E. Comstock, Michael H. Malamy, Blanca Barquera
Publikováno v:
mBio, Vol 11, Iss 1 (2020)
ABSTRACT In bacteria, the respiratory pathways that drive molecular transport and ATP synthesis include a variety of enzyme complexes that utilize different electron donors and acceptors. This property allows them to vary the efficiency of energy con
Externí odkaz:
https://doaj.org/article/12244fa6b43343798eb241ea4fed69c0
Autor:
Markus B. Tomek, Bettina Janesch, Matthias L. Braun, Manfred Taschner, Rudolf Figl, Clemens Grünwald-Gruber, Michael J. Coyne, Markus Blaukopf, Friedrich Altmann, Paul Kosma, Hanspeter Kählig, Laurie E. Comstock, Christina Schäffer
Publikováno v:
Biomolecules, Vol 11, Iss 12, p 1795 (2021)
Diverse members of the Bacteroidetes phylum have general protein O-glycosylation systems that are essential for processes such as host colonization and pathogenesis. Here, we analyzed the function of a putative fucosyltransferase (FucT) family that i
Externí odkaz:
https://doaj.org/article/2b317889268042088c5416c05ddfd2c9
Publikováno v:
mBio, Vol 10, Iss 4 (2019)
ABSTRACT Studies of the gut microbiota have dramatically increased in recent years as the importance of this microbial ecosystem to human health and disease is better appreciated. The Bacteroidales are the most abundant order of bacteria in the healt
Externí odkaz:
https://doaj.org/article/1fc06d832ea54e9aa87c5317f5763514
Autor:
Maria Chatzidaki-Livanis, Michael J. Coyne, Kevin G. Roelofs, Rahul R. Gentyala, Jarreth M. Caldwell, Laurie E. Comstock
Publikováno v:
mBio, Vol 8, Iss 6 (2017)
ABSTRACT Human gut Bacteroides species produce different types of toxins that antagonize closely related members of the gut microbiota. Some are toxic effectors delivered by type VI secretion systems, and others are non-contact-dependent secreted ant
Externí odkaz:
https://doaj.org/article/b82fd22b110442cea1336cccb91552ed
Autor:
Kevin G. Roelofs, Michael J. Coyne, Rahul R. Gentyala, Maria Chatzidaki-Livanis, Laurie E. Comstock
Publikováno v:
mBio, Vol 7, Iss 4 (2016)
ABSTRACT We recently showed that human gut Bacteroidales species secrete antimicrobial proteins (BSAPs), and we characterized in vitro the first such BSAP produced by Bacteroides fragilis. In this study, we identified a second potent BSAP produced by
Externí odkaz:
https://doaj.org/article/886b9f5567ef4d3cbd05cecdb11fd486