Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Laurie A Steiner"'
Autor:
Laurie A Steiner, Vincent Schulz, Yelena Makismova, Kimberly Lezon-Geyda, Patrick G Gallagher
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0155378 (2016)
BackgroundCTCF and cohesinSA-1 are regulatory proteins involved in a number of critical cellular processes including transcription, maintenance of chromatin domain architecture, and insulator function. To assess changes in the CTCF and cohesinSA-1 in
Externí odkaz:
https://doaj.org/article/1d3fa8eb8ee84207be0e337560c0f2c7
Autor:
Jacquelyn A. Myers, Tyler Couch, Zachary Murphy, Jeffrey Malik, Michael Getman, Laurie A. Steiner
Publikováno v:
Epigenetics & Chromatin, Vol 13, Iss 1, Pp 1-13 (2020)
Abstract Background SETD8 is the sole methyltransferase capable of mono-methylating histone H4, lysine 20. SETD8 and H4K20me1 play a role in a number of essential biologic processes, including cell cycle progression, establishment of higher order chr
Externí odkaz:
https://doaj.org/article/21e5f727a96545f08e136f0f08e40780
Autor:
Ebba, Alkhunaizi, Nicole, Martin, Angie C, Jelin, Mara, Rosner, Diana J, Bailey, Laurie A, Steiner, Saquib, Lakhani, Weizhen, Ji, Philip J, Katzman, Katherine R, Forster, Olga, Jarinova, Patrick, Shannon, David, Chitayat
Publikováno v:
American Journal of Medical Genetics Part A. 191:760-769
Arthrogryposis multiplex congenita (AMC) [also known as multiple joints contracture or Fetal Akinesia Deformation Sequence (FADS)] is etiologically a heterogeneous condition with an estimated incidence of approximately 1 in 3000 live births and much
Publikováno v:
Cell Reports, Vol 21, Iss 9, Pp 2376-2383 (2017)
Erythropoiesis is a highly regulated process that generates enucleate red blood cells from committed erythroid progenitors. Chromatin condensation culminating in enucleation is a defining feature of this process. Setd8 is the sole enzyme that can mon
Externí odkaz:
https://doaj.org/article/8366e27eb64b4227b23ca6021af35aab
Autor:
Bing Guo, Scott C. Friedland, William Alexander, Jacquelyn A. Myers, Wenjia Wang, Michael R. O’Dell, Michael Getman, Christa L. Whitney-Miller, Diana Agostini-Vulaj, Aaron R. Huber, Stephano S. Mello, Paula M. Vertino, Hartmut K. Land, Laurie A. Steiner, Aram F. Hezel
Publikováno v:
Cell reports. 40(9)
Activating KRAS mutations and functional loss of members of the SWI/SNF complex, including ARID1A, are found together in the primary liver tumor cholangiocarcinoma (CC). How these mutations cooperate to promote CC has not been established. Using muri
Autor:
Yuefeng Tang, Mushran Kahn, Julien Papoin, Hongxia Yan, Anupama Narla, James Palis, Laurie A. Steiner, Patrick G. Gallagher, Jeffrey M Lipton, Mohandas Narla, Lionel Blanc
Publikováno v:
Blood. 140:2946-2946
Autor:
Jayme L. Olsen, Kathleen E. McGrath, Kristin Murphy, Taylor Schofield, Michael Getman, Mohandas Narla, Lionel Blanc, Vincent P Schulz, Patrick G. Gallagher, Laurie A. Steiner, James Palis
Publikováno v:
Blood. 140:8152-8152
Publikováno v:
Blood. 140:704-704
Autor:
Brian M. Dulmovits, Yuefeng Tang, Julien Papoin, Mingzhu He, Jianhua Li, Huan Yang, Meghan E. Addorisio, Lauren Kennedy, Mushran Khan, Elena Brindley, Ryan J. Ashley, Cheryl Ackert-Bicknell, John Hale, Ryo Kurita, Yukio Nakamura, Betty Diamond, Betsy J. Barnes, Olivier Hermine, Patrick G. Gallagher, Laurie A. Steiner, Jeffrey M. Lipton, Naomi Taylor, Narla Mohandas, Ulf Andersson, Yousef Al-Abed, Kevin J. Tracey, Lionel Blanc
Publikováno v:
Blood. 139(21)
Anemia of inflammation, also known as anemia of chronic disease, is refractory to erythropoietin (EPO) treatment, but the mechanisms underlying the EPO refractory state are unclear. Here, we demonstrate that high mobility group box-1 protein (HMGB1),
Autor:
Jacquelyn Myers, Laurie A. Steiner, Vincent P. Schulz, Tyler A Couch, Narla Mohandas, Zachary C. Murphy, Michael Getman, Cal D. Palumbo, Hongxia Yan, Kristin Murphy, Kimberly Lezon-Geyda, Patrick G. Gallagher
Publikováno v:
Blood
The terminal maturation of human erythroblasts requires significant changes in gene expression in the context of dramatic nuclear condensation. Defects in this process are associated with inherited anemias and myelodysplastic syndromes. The progressi