Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Laurie, Volak"'
Autor:
Lyn H, Jones, Constance A, Mitchell, Lise, Loberg, Mira, Pavkovic, Mohan, Rao, Ruth, Roberts, Katie, Stamp, Laurie, Volak, Matthias B, Wittwer, Syril, Pettit
Publikováno v:
Nature Reviews Drug Discovery. 21:401-402
Autor:
Thomas C.K. Chan, Mark A. Ashwell, Jean-Marc Lapierre, Christopher Brassard, Cathy Bull, Susan Cornell-Kennon, Sudharshan Eathiraj, Dennis S. France, Jason Hill, Steffi Koerner, Eoin Kelleher, Darin Kizer, Yanbin Liu, Jeff Link, Sapna Makhija, Magdi Moussa, Nivedita Namdev, Robert Nicewonger, Uma Uppalapati, Rocio Palma, Jeff Szwaya, Manish Tandon, David Vensel, Laurie Volak, Erika Volckova, Neil Westland, Hui Wu, Rui-Yang Yang
Publikováno v:
Cancer Research. 72:LB-1
Herein we describe the implementation of a biochemical and biophysical screening strategy to discover small molecules that inhibit Akt through a mechanism distinct from ATP-competitive inhibitors. A series of novel derivatives of the core scaffold 3H