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Autor:
Remesh, Soumya G, Merz, Gregory E, Brilot, Axel F, Chio, Un Seng, Rizo, Alexandrea N, Pospiech, Thomas H, Lui, Irene, Laurie, Mathew T, Glasgow, Jeff, Le, Chau Q, Zhang, Yun, Diwanji, Devan, Hernandez, Evelyn, Lopez, Jocelyne, Mehmood, Hevatib, Pawar, Komal Ishwar, Pourmal, Sergei, Smith, Amber M, Zhou, Fengbo, QCRG Structural Biology Consortium, DeRisi, Joseph, Kortemme, Tanja, Rosenberg, Oren S, Glasgow, Anum, Leung, Kevin K, Wells, James A, Verba, Kliment A
Publikováno v:
Structure (London, England : 1993), vol 31, iss 3
The SARS-CoV-2 Omicron variant, with 15 mutations in Spike receptor-binding domain (Spike-RBD), renders virtually all clinical monoclonal antibodies against WT SARS-CoV-2 ineffective. We recently engineered theSARS-CoV-2 host entry receptor, ACE2, to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::caf7bc62ae64e02b98b60286af094cf9
https://escholarship.org/uc/item/8nf664kq
https://escholarship.org/uc/item/8nf664kq
Autor:
Remesh SG; Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, CA - 94158, USA.; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA - 94158, USA., Merz GE; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA - 94158, USA., Brilot AF; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA - 94158, USA., Chio US; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA - 94158, USA., Rizo AN; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA - 94158, USA., Pospiech TH Jr; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA - 94158, USA., Lui I; Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, CA - 94158, USA., Laurie MT; Department of Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA - 94158, USA., Glasgow J; Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, CA - 94158, USA., Le CQ; Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, CA - 94158, USA., Zhang Y; Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, CA - 94158, USA., Diwanji D; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA - 94158, USA., Hernandez E; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA - 94158, USA., Lopez J; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA - 94158, USA., Pawar KI; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA - 94158, USA., Pourmal S; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA - 94158, USA., Smith AM; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA - 94158, USA., Zhou F; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA - 94158, USA., DeRisi J; Department of Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA - 94158, USA.; Chan Zuckerberg Biohub, San Francisco, CA - 94158, USA., Kortemme T; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA - 94158, USA.; QBI, University of California, San Francisco, CA 94158, USA.; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, CA - 94158, USA.; The University of California, Berkeley-University of California, San Francisco Graduate Program in Bioengineering, University of California, San Francisco, CA - 94158, USA., Rosenberg OS; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA - 94158, USA., Glasgow A; Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY 10032, USA., Leung KK; Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, CA - 94158, USA., Wells JA; Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, CA - 94158, USA.; Chan Zuckerberg Biohub, San Francisco, CA - 94158, USA.; Department of Cellular & Molecular Pharmacology, University of California San Francisco, San Francisco, CA - 94158, USA., Verba KA; Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, CA - 94158, USA.; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA - 94158, USA.; QBI, University of California, San Francisco, CA 94158, USA.; Lead contact.
Publikováno v:
BioRxiv : the preprint server for biology [bioRxiv] 2022 Aug 10. Date of Electronic Publication: 2022 Aug 10.
