Výsledky vyhledávání - "Laurie, Lambot"

Akademický článek

Neurons and cardiomyocytes derived from induced pluripotent stem cells as a model for mitochondrial defects in Friedreich’s ataxia

Autor: Aurore Hick, Marie Wattenhofer-Donzé, Satyan Chintawar, Philippe Tropel, Jodie P. Simard, Nadège Vaucamps, David Gall, Laurie Lambot, Cécile André, Laurence Reutenauer, Myriam Rai, Marius Teletin, Nadia Messaddeq, Serge N. Schiffmann, Stéphane Viville, Christopher E. Pearson, Massimo Pandolfo, Hélène Puccio

Publikováno v: Disease Models & Mechanisms, Vol 6, Iss 3, Pp 608-621 (2013)

SUMMARY Friedreich’s ataxia (FRDA) is a recessive neurodegenerative disorder commonly associated with hypertrophic cardiomyopathy. FRDA is due to expanded GAA repeats within the first intron of the gene encoding frataxin, a conserved mitochondrial

Externí odkaz: https://doaj.org/article/8628c6091f1b41bfa49ec4ee6cf62b74

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CRAC channels regulate astrocyte Ca

Autor: Anna B, Toth, Kotaro, Hori, Michaela M, Novakovic, Natalie G, Bernstein, Laurie, Lambot, Murali, Prakriya

Publikováno v: Science signaling. 12(582)

Astrocytes are the major glial subtype in the brain and mediate numerous functions ranging from metabolic support to gliotransmitter release through signaling mechanisms controlled by Ca(2+). Despite intense interest, the Ca(2+) influx pathways in as

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::00a8f18b59aa99088ab17f15b8652d55
https://pubmed.ncbi.nlm.nih.gov/31113852

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CRAC channels regulate astrocyte Ca 2+ signaling and gliotransmitter release to modulate hippocampal GABAergic transmission

Autor: Michaela M. Novakovic, Natalie G. Bernstein, Anna B. Toth, Laurie Lambot, Murali Prakriya, Kotaro Hori

Publikováno v: Science Signaling. 12

Astrocytes are the major glial subtype in the brain and mediate numerous functions ranging from metabolic support to gliotransmitter release through signaling mechanisms controlled by Ca2+. Despite intense interest, the Ca2+ influx pathways in astroc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5fb1bfe23bcabc12f76593c152271928
https://doi.org/10.1126/scisignal.aaw5450

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Striatopallidal Neuron NMDA Receptors Control Synaptic Connectivity, Locomotor, and Goal-Directed Behaviors

Autor: Yuquing Li, Elena Chaves Rodriguez, David Gall, Alban de Kerchove d'Exaerde, Serge N. Schiffmann, Delphine Houtteman, Laurie Lambot

Publikováno v: The Journal of Neuroscience. 36:4976-4992

The basal ganglia (BG) control action selection, motor programs, habits, and goal-directed learning. The striatum, the principal input structure of BG, is predominantly composed of medium-sized spiny neurons (MSNs). Arising from these spatially inter

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b17aa12e503f3de61d0a902bbd57a2f
https://doi.org/10.1523/jneurosci.2717-15.2016

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Long-range inhibitory intersection of a retrosplenial thalamocortical circuit by apical tuft-targeting CA1 neurons

Autor: Jelena Radulovic, Laurie Lambot, Lynn Y. Ren, Gordon M. Shepherd, Xiaojian Li, Naoki Yamawaki

Publikováno v: Nature neuroscience

Dorsal hippocampus, retrosplenial cortex (RSC), and anterior thalamic nuclei (ATN) interact to mediate diverse cognitive functions, but the cellular basis for these interactions is unclear. We hypothesized a long-range circuit converging in layer 1 (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9521a61c430bd4fddfde818f0e68466
https://pubmed.ncbi.nlm.nih.gov/30858601

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Vers une électrophysiologie optiquein vivo

Autor: David Gall, Laurie Lambot

Publikováno v: médecine/sciences. 32:768-770

Optical imaging of voltage indicators is a promising approach for detecting the activity of neuronal circuits with high spatial and temporal resolution. In this context, genetically encoded voltage indicators, combining genetic targeting and optical

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::30e8729c28f41d49370e0ba495507d23
https://doi.org/10.1051/medsci/20163208026

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[Towards optical in vivo electrophysiology]

Autor: Laurie, Lambot, David, Gall

Publikováno v: Medecine sciences : M/S. 32(8-9)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0ca1f51a8448acb01fc70859bdd9bc54
https://pubmed.ncbi.nlm.nih.gov/27615186

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Hallmarks of Alzheimer’s Disease in Stem-Cell-Derived Human Neurons Transplanted into Mouse Brain

Publikováno v: Neuron. 93:1066-1081.e8

Human pluripotent stem cells (PSCs) provide a unique entry to study species-specific aspects of human disorders such as Alzheimer's disease (AD). However, in vitro culture of neurons deprives them of their natural environment. Here we transplanted hu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cc5a436a8bc0f24b08321b5e5eb523e
https://doi.org/10.1016/j.neuron.2017.02.001

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Genetic deletion of PDE10A selectively impairs incentive salience attribution and decreases medium spiny neuron excitability

Autor: Laurie Lambot, Serge N. Schiffmann, Rudi D'Hooge, Greet Vanhoof, Adam Raes, Jean-François De Backer, Elisabeth Piccart, David Gall

Publikováno v: Behavioural brain research. 268

The striatum is the main input structure to the basal ganglia and consists mainly out of medium spiny neurons. The numerous spines on their dendrites render them capable of integrating cortical glutamatergic inputs with a motivational dopaminergic si

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e3228b0e459ef857e9f6e92afa6d1f1
https://pubmed.ncbi.nlm.nih.gov/24698799

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Neurons and cardiomyocytes derived from induced pluripotent stem cells as a model for mitochondrial defects in Friedreich's ataxia

Autor: Satyan Chintawar, David Gall, Christopher E. Pearson, Myriam Rai, Massimo Pandolfo, Nadège Vaucamps, Hélène Puccio, Marius Teletin, Marie Wattenhofer-Donzé, Jodie P. Simard, Laurie Lambot, Laurence Reutenauer, Serge N. Schiffmann, Aurore Hick, Philippe Tropel, Cécile André, Nadia Messaddeq, Stéphane Viville

Publikováno v: Disease Models and Mechanisms, 6 (3
Disease Models & Mechanisms, Vol 6, Iss 3, Pp 608-621 (2013)
Disease Models & Mechanisms
Disease Models & Mechanisms; Vol 6

Friedreich's ataxia (FRDA) is a recessive neurodegenerative disorder commonly associated with hypertrophic cardiomyopathy. FRDA is due to expanded GAA repeats within the first intron of the gene encoding frataxin, a conserved mitochondrial protein in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f94ed26659419dc68afde45128d0dac
https://doi.org/10.1242/dmm.010900

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