Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Laurie, Guitou"'
Autor:
Helene Tronchere, Mathieu Cinato, Andrei Timotin, Laurie Guitou, Camille Villedieu, Helene Thibault, Delphine Baetz, Bernard Payrastre, Philippe Valet, Angelo Parini, Oksana Kunduzova, Frederic Boal
Publikováno v:
EMBO Molecular Medicine, Vol 9, Iss 6, Pp 770-785 (2017)
Abstract PIKfyve is an evolutionarily conserved lipid kinase that regulates pleiotropic cellular functions. Here, we identify PIKfyve as a key regulator of cardiometabolic status and mitochondrial integrity in chronic diet‐induced obesity. In vitro
Externí odkaz:
https://doaj.org/article/ffde4b6b99b64e4fbcf721fdde0f4a1e
Autor:
Mathieu, Cinato, Laurie, Guitou, Amira, Saidi, Andrei, Timotin, Erwan, Sperazza, Thibaut, Duparc, Sergey N, Zolov, Sai Srinivas Panapakkam, Giridharan, Lois S, Weisman, Laurent O, Martinez, Jerome, Roncalli, Oksana, Kunduzova, Helene, Tronchere, Frederic, Boal
Publikováno v:
Theranostics
Rationale: TGFβ signaling pathway controls tissue fibrotic remodeling, a hallmark in many diseases leading to organ injury and failure. In this study, we address the role of Apilimod, a pharmacological inhibitor of the lipid kinase PIKfyve, in the r
Autor:
Bernard Payrastre, Philippe Valet, Hélène Thibault, Hélène Tronchère, Laurie Guitou, Delphine Baetz, Andrei Timotin, Angelo Parini, Frederic Boal, Oksana Kunduzova, Mathieu Cinato, Camille Villedieu
Publikováno v:
EMBO Molecular Medicine
EMBO Molecular Medicine, Wiley Open Access, 2017, 9 (6), pp.770-785. ⟨10.15252/emmm.201607096⟩
EMBO Molecular Medicine, Wiley Open Access, 2017, 9 (6), pp.770-785. ⟨10.15252/emmm.201607096⟩
International audience; PIKfyve is an evolutionarily conserved lipid kinase that regulates pleiotropic cellular functions. Here, we identify PIKfyve as a key regulator of cardiometabolic status and mitochondrial integrity in chronic diet-induced obes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::411499d93c3593c5ddaffbcb897789cf
https://hal.archives-ouvertes.fr/hal-01827485
https://hal.archives-ouvertes.fr/hal-01827485