Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Laurie, Gay"'
Autor:
Zachary R. Chalmers, Caitlin F. Connelly, David Fabrizio, Laurie Gay, Siraj M. Ali, Riley Ennis, Alexa Schrock, Brittany Campbell, Adam Shlien, Juliann Chmielecki, Franklin Huang, Yuting He, James Sun, Uri Tabori, Mark Kennedy, Daniel S. Lieber, Steven Roels, Jared White, Geoffrey A. Otto, Jeffrey S. Ross, Levi Garraway, Vincent A. Miller, Phillip J. Stephens, Garrett M. Frampton
Publikováno v:
Genome Medicine, Vol 9, Iss 1, Pp 1-14 (2017)
Abstract Background High tumor mutational burden (TMB) is an emerging biomarker of sensitivity to immune checkpoint inhibitors and has been shown to be more significantly associated with response to PD-1 and PD-L1 blockade immunotherapy than PD-1 or
Externí odkaz:
https://doaj.org/article/fb907a4b3aaf43769173e9ac0018e2eb
Autor:
Doron Lipson, Jack F. Shern, Trevor J. Pugh, Soheil Meshinchi, John M. Maris, Katherine A. Janeway, Philip J. Stephens, Vincent A. Miller, Blair Glanville, Alexis Germain, Vinny Faso, Hilary Davies, Joana Buxhaku, Jeffrey S. Ross, Rachel L. Erlich, Laurie Gay, Siraj Ali, Daniel Spritz, Samantha Morley, James X. Sun, Garrett M. Frampton, James Suh, Shakti Ramkissoon, Jo-Anne Vergilio, Julia Elvin, Jie He, Mark Bailey, Juliann Chmielecki
Long tail distribution of the top 50 altered genes in pediatric sarcoma (S1); Long tail distribution of the top 50 altered genes in pediatric extracranial embryonal tumors (S2); Long tail distribution of the top 50 altered genes in pediatric brain tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c1787586c646efaf2a677928246eca2
https://doi.org/10.1158/0008-5472.22414374
https://doi.org/10.1158/0008-5472.22414374
Autor:
Alessandro D. Santin, Peter E. Schwartz, Elena S. Ratner, Yuting Liu, David L. Rimm, Julia Elvin, Laurie Gay, Luca Zammataro, Jungmin Choi, Natalia Buza, Stefania Bellone
Purpose: Ovarian carcinoma no longer responsive to surgery and chemotherapy remains an incurable disease. Alternative therapeutic options remain desperately needed.Patients and Methods: We describe a heavily pretreated patient with ovarian cancer wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18fb5ac0f8586ad2200c3832fb60d27b
https://doi.org/10.1158/1078-0432.c.6525833
https://doi.org/10.1158/1078-0432.c.6525833
Autor:
Doron Lipson, Jack F. Shern, Trevor J. Pugh, Soheil Meshinchi, John M. Maris, Katherine A. Janeway, Philip J. Stephens, Vincent A. Miller, Blair Glanville, Alexis Germain, Vinny Faso, Hilary Davies, Joana Buxhaku, Jeffrey S. Ross, Rachel L. Erlich, Laurie Gay, Siraj Ali, Daniel Spritz, Samantha Morley, James X. Sun, Garrett M. Frampton, James Suh, Shakti Ramkissoon, Jo-Anne Vergilio, Julia Elvin, Jie He, Mark Bailey, Juliann Chmielecki
Gene lists for Version 1 of the FoundationOne Assay (S1); Gene lists for Version 2 of the FoundationOne Assay (S2); Gene lists for Version 3 of the FoundationOne Assay (S3); Gene lists for Version 4 of the FoundationOne Assay (S4); Gene lists for Ver
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d519b7259eab3f249fe92b2affbb4a8
https://doi.org/10.1158/0008-5472.22414371.v1
https://doi.org/10.1158/0008-5472.22414371.v1
Autor:
Alessandro D. Santin, Peter E. Schwartz, Elena S. Ratner, Yuting Liu, David L. Rimm, Julia Elvin, Laurie Gay, Luca Zammataro, Jungmin Choi, Natalia Buza, Stefania Bellone
Supplemental legend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f4694cdaad0cb088802983fbbd05976
https://doi.org/10.1158/1078-0432.22464854
https://doi.org/10.1158/1078-0432.22464854
Autor:
Sarki A. Abdulkadir, Francis J. Giles, Young K. Chae, Massimo Cristofanilli, Siraj M. Ali, Julia A. Elvin, Laurie Gay, Jeffrey S. Ross, Timothy M. Kuzel, Richard B. Lanman, Rebecca J. Nagy, Rubens B. Costa, Ximing J. Yang, HuiYing Han, Kenji Unno, Vinay Sagar, Ami N. Shah, Sahithi Pamarthy, Benedito A. Carneiro
Figure S1 ALK genomic alterations and mRNA expression in human cancers. Figure S2 Efficacy of ALK inhibitors in prostate cancer cell lines. Table S1 Summary of mutations and their percentages identified by ctDNA profiling.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b1a8d1b8fbbd18b54d0ed1b4de078e1
https://doi.org/10.1158/1078-0432.22474914.v1
https://doi.org/10.1158/1078-0432.22474914.v1
Autor:
Doron Lipson, Jack F. Shern, Trevor J. Pugh, Soheil Meshinchi, John M. Maris, Katherine A. Janeway, Philip J. Stephens, Vincent A. Miller, Blair Glanville, Alexis Germain, Vinny Faso, Hilary Davies, Joana Buxhaku, Jeffrey S. Ross, Rachel L. Erlich, Laurie Gay, Siraj Ali, Daniel Spritz, Samantha Morley, James X. Sun, Garrett M. Frampton, James Suh, Shakti Ramkissoon, Jo-Anne Vergilio, Julia Elvin, Jie He, Mark Bailey, Juliann Chmielecki
Pediatric cancers are generally characterized by low mutational burden and few recurrently mutated genes. Recent studies suggest that genomic alterations may help guide treatment decisions and clinical trial selection. Here, we describe genomic profi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4da4fd89d6550e13c627bd12d2463218
https://doi.org/10.1158/0008-5472.c.6508959.v1
https://doi.org/10.1158/0008-5472.c.6508959.v1
Autor:
Sarki A. Abdulkadir, Francis J. Giles, Young K. Chae, Massimo Cristofanilli, Siraj M. Ali, Julia A. Elvin, Laurie Gay, Jeffrey S. Ross, Timothy M. Kuzel, Richard B. Lanman, Rebecca J. Nagy, Rubens B. Costa, Ximing J. Yang, HuiYing Han, Kenji Unno, Vinay Sagar, Ami N. Shah, Sahithi Pamarthy, Benedito A. Carneiro
Purpose: Small cell carcinoma of the prostate (SCCP) is an aggressive disease that can arise de novo or by transdifferentiation from prostate adenocarcinoma. Alterations in anaplastic lymphoma kinase (ALK) gene are involved in neuroblastoma, lung can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d5214bf1fbee91715c0ba541ca1ed4c
https://doi.org/10.1158/1078-0432.c.6528936
https://doi.org/10.1158/1078-0432.c.6528936
Autor:
Alessandro D. Santin, Peter E. Schwartz, Elena S. Ratner, Yuting Liu, David L. Rimm, Julia Elvin, Laurie Gay, Luca Zammataro, Jungmin Choi, Natalia Buza, Stefania Bellone
Supplementary Figure 1. Structure and breakpoint DNA sequence of CD274 (lower case) and PLGRKT 32bp insertion (upper case) in the high grade ovarian carcinoma.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::633fa3072e4141b2789631e9efed941b
https://doi.org/10.1158/1078-0432.22464848.v1
https://doi.org/10.1158/1078-0432.22464848.v1
Autor:
Elizabeth R. Starks, Victoria Carlton, Veena Rajaraman, Katya Kosheleva, Tamsen Dunn, Nick Kamps-Hughes, Laurie Gay, Meaghan Russell, Sarah Albritton, John J. Vincent, Nhu Ngo
Publikováno v:
Cancer Research. 82:1230-1230
Introduction: NGS-based tests that include biomarkers such as microsatellite instability (MSI) and tumor mutational burden (TMB) increase patient access to immune checkpoint inhibitors and improve the personalization of cancer care. Tumor-only NGS te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9611052022ea76b4e3394682253e8a41
https://doi.org/10.1158/1538-7445.am2022-1230
https://doi.org/10.1158/1538-7445.am2022-1230