Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Laurice A. Kopta"'
Autor:
Gabriela Borilova, Nguyen Xuan Hoa, Guangzhi Zhang, Jan A.M. Langermans, Dennis L. Foss, Hiroyoshi Ota, Han Liu, Jay V. Solnick, Sara K. Lindén, Maria Pia Franciosini, Aizhen Guo, O. O. Omotosho, Bram Flahou, Patrizia Casagrande Proietti, Frank Pasmans, Masahiko Nakamura, Jukka Corander, Sofie De Bruyckere, Anders Øverby, Mirko Rossi, Takehisa Matsumoto, Jaco Bakker, Chloë De Witte, Annemieke Smet, Miriam E. Martin, Hidenori Matsui, Freddy Haesebrouck, Edwin Heuvelman, Jani O'Rourke, Richard Ducatelle, Ana Paula Frederico Rodrigues Loureiro Bracarense, Le Duc Ngoan, Laurice A. Kopta
Publikováno v:
The ISME journal : multidisciplinary journal of microbial ecology
The ISME journal, vol 12, iss 1
The ISME journal, vol 12, iss 1
Helicobacter suis is the second most prevalent Helicobacter species in the stomach of humans suffering from gastric disease. This bacterium mainly inhabits the stomach of domesticated pigs, in which it causes gastric disease, but it appears to be abs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c943d826d115b307108fa7eee67fd6a
http://hdl.handle.net/11391/1423838
http://hdl.handle.net/11391/1423838
Autor:
Funk Lee Andrew, Robert Anstadt, Rebecca M. Anderson, Jeffrey A. Pfefferkorn, Matthew T. Reding, Richard A. Nugent, Robert E. Kilkuskie, John A. Shelly, Francis J. Schwende, Melissa S. Harris, Mark A. Mitchell, Meredith Greene, Barry C. Finzel, Laurice A. Kopta, Peter A. Wells, Rebecca J. Gross
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 15:2481-2486
A novel series of nonnucleoside HCV NS5B polymerase inhibitors were prepared from (2Z)-2-(benzoylamino)-3-(5-phenyl-2-furyl)acrylic acid, a high throughput screening lead. SAR studies combined with structure based drug design focusing on the southern
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cb50dc565e73f2cfc26b76321b19bc0
https://doi.org/10.1016/j.bmcl.2005.03.066
https://doi.org/10.1016/j.bmcl.2005.03.066
Autor:
Stephen T. Schlachter, Richard C. Thomas, T. J. Poel, David R. Graber, Robert A. Olmsted, Laurice A. Kopta, Megan Murphy, Richard A. Nugent, S M Swaney, Keiser Bj, Joel Morris, Y. Yagi, Cleek Gary J, W G Tarpley, S M Poppe, Donn G. Wishka
Publikováno v:
Journal of Medicinal Chemistry. 41:3793-3803
A series of pyrimidine thioethers was synthesized and evaluated for inhibitory properties against wild-type HIV-1 reverse transcriptase (RT) and an RT carrying the resistance-conferring mutation P236L. Modifications of both the pyrimidine and the fun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4261683cacd8cb18181116f242af220
https://doi.org/10.1021/jm9800806
https://doi.org/10.1021/jm9800806
Autor:
Richard A. Nugent, Donn G. Wishka, Lester A. Dolak, Azhwarsamy Jeganathan, Eric P. Seest, Laurice A. Kopta, Randall G. Stehle, Joel Morris, Wendy L. White, Stephen T. Schlachter, Janice M. Friis, Susan M. Poppe, Wade J. Adams, Murphy Michael J, David R. Graber, Robert A. Olmsted, Fusen Han, John D. Hosley, Cleek Gary J, Richard L. Voorman, Poel Toni-Jo, and W. Gary Tarpley, William Watt, Keiser Bj, Y. Yagi, Kevin Stefanski, Richard C. Thomas, Steven M. Swaney, Thomas M. Castle
Publikováno v:
Journal of Medicinal Chemistry. 41:1357-1360
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2821bb7f749a376a1a2d6c7a50b95408
https://doi.org/10.1021/jm9801049
https://doi.org/10.1021/jm9801049
Autor:
Carolyn Biles, Keiser Bj, David B. Evans, Joel Morris, Richard L. Voorman, Raymond A. Morge, Satish K. Sharma, Laurice A. Kopta, John D. Hosley, Janice M. Friis, W G Tarpley, Wade J. Adams, Kevin Stefanski, Donna L. Romero, Randall G. Stehle, Donn G. Wishka, Richard C. Thomas, Y. Yagi, T. J. Poel, Robert A. Olmsted
Publikováno v:
Journal of Medicinal Chemistry. 39:3769-3789
A novel class of bis(heteroaryl)piperazine (BHAP) analogs which possesses the ability to inhibit NNRTI (non-nucleoside reverse transcriptase inhibitor) resistant recombinant HIV-1 reverse transcriptase (RT) and NNRTI resistant variants of HIV-1 has b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e01ee3a1aeac60f7c3685b5ac0d3ab3a
https://doi.org/10.1021/jm960158n
https://doi.org/10.1021/jm960158n
Autor:
Jeffrey A. Pfefferkorn, Richard Nugent, Rebecca J. Gross, Meredith Greene, Mark A. Mitchell, Matthew T. Reding, Lee A. Funk, Rebecca Anderson, Peter A. Wells, John A. Shelly, Robert Anstadt, Barry C. Finzel, Melissa S. Harris, Robert E. Kilkuskie, Laurice A. Kopta, Francis J. Schwende
Publikováno v:
Bioorganicmedicinal chemistry letters. 15(11)
A novel series of non-nucleoside HCV NS5B polymerase inhibitors was prepared from a (2Z)-2-benzoylamino-3-(4-phenoxy-phenyl)-acrylic acid template. Solution and solid phase analog synthesis focused on the northern region of the template combined with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4633f41cba42c95cd8ac389041105a45
https://pubmed.ncbi.nlm.nih.gov/15911260
https://pubmed.ncbi.nlm.nih.gov/15911260
Autor:
T. J. Poel, Michael J. Genin, Irene W. Althaus, Laurice A. Kopta, Carolyn Biles, Wade J. Adams, Donna L. Romero, Richard L. Voorman, Keiser Bj, Jan M. Friis, Richard C. Thomas, Y. Yagi, Robert A. Olmsted, Fritz Reusser
Publikováno v:
Journal of medicinal chemistry. 39(26)
The major route of metabolism of the bis(heteroaryl)piperazine (BHAP) class of reverse transcriptase inhibitors (RTIs), atevirdine and delavirdine, is via oxidative N-dealkylation of the 3-ethyl- or 3-isopropylamino substituent on the pyridine ring.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1f8faf87835497fc1cc167fd36e9830
https://pubmed.ncbi.nlm.nih.gov/8978855
https://pubmed.ncbi.nlm.nih.gov/8978855
Publikováno v:
Pediatric infectious disease. 5(1)
The cost effectiveness of home care for pediatric tracheostomy patients has become a concern. One major cost component of this care is the tracheal suction catheter. This study was designed to assess the microbiologic effectiveness of a practical cle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59cb16a1cb0529a62a57a22b0fa2d2ee
https://pubmed.ncbi.nlm.nih.gov/3945577
https://pubmed.ncbi.nlm.nih.gov/3945577