Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Laurianne Bonnet"'
Autor:
Laurianne Bonnet, Ida Alexandersson, Ritesh K. Baboota, Tobias Kroon, Jan Oscarsson, Ulf Smith, Jeremie Boucher
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Cellular senescence is a state of irreversible cell cycle arrest and has been shown to play a key role in many diseases, including metabolic diseases. To investigate the potential contribution of hepatocyte cellular senescence to the metabolic derang
Externí odkaz:
https://doaj.org/article/e07ac7d9dbb3475c9b853917c66c53c3
Autor:
Roxana Khatib Shahidi, Jenny M Hoffmann, Shahram Hedjazifar, Laurianne Bonnet, Ritesh K Baboota, Stephanie Heasman, Christopher Church, Ivet Elias, Fatima Bosch, Jeremie Boucher, Ann Hammarstedt, Ulf Smith
Publikováno v:
PLoS ONE, Vol 16, Iss 2, p e0247300 (2021)
ObjectiveGremlin 1 (GREM1) is a secreted BMP2/4 inhibitor which regulates commitment and differentiation of human adipose precursor cells and prevents the browning effect of BMP4. GREM1 is an insulin antagonist and serum levels are high in type 2 dia
Externí odkaz:
https://doaj.org/article/56874d5e62914cb6835372b1a006b4c0
Autor:
Tobias Kroon, Matthew Harms, Stefanie Maurer, Laurianne Bonnet, Ida Alexandersson, Anna Lindblom, Andrea Ahnmark, Daniel Nilsson, Peter Gennemark, Gavin O'Mahony, Victoria Osinski, Coleen McNamara, Jeremie Boucher
Publikováno v:
Molecular Metabolism, Vol 36, Iss , Pp - (2020)
Objective: Peroxisome proliferator-activated receptors (PPARs) are key transcription factors that regulate adipose development and function, and the conversion of white into brown-like adipocytes. Here we investigated whether PPARα and PPARγ activa
Externí odkaz:
https://doaj.org/article/c8f7d5b18d4a454e9d17350c34792a8f
Autor:
Laurianne Bonnet, Marielle Margier, Ljubica Svilar, Charlene Couturier, Emmanuelle Reboul, Jean-Charles Martin, Jean-François Landrier, Catherine Defoort
Publikováno v:
Nutrients, Vol 11, Iss 9, p 1977 (2019)
Vitamin D metabolism is actively modulated in adipose tissue during obesity. To better investigate this process, we develop a specific LC-HRMS/MS method that can simultaneously quantify three vitamin D metabolites, i.e., cholecalciferol, 25-hydroxyvi
Externí odkaz:
https://doaj.org/article/1bbf66d1254d42b5acfd779548240c4f
Autor:
Ritesh K. Baboota, Aidin Rawshani, Laurianne Bonnet, Xiangyu Li, Hong Yang, Adil Mardinoglu, Tamar Tchkonia, James L. Kirkland, Anne Hoffmann, Arne Dietrich, Jeremie Boucher, Matthias Blüher, Ulf Smith
Publikováno v:
Nature Metabolism. 4:1007-1021
The role of hepatic cell senescence in human non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) is not well understood. To examine this, we performed liver biopsies and extensive characterization of 58 individuals with
Autor:
Jenny M. Hoffmann, Ivet Elias, Roxana Khatib Shahidi, Jeremie Boucher, Ann Hammarstedt, Christopher Church, Shahram Hedjazifar, Fatima Bosch, Laurianne Bonnet, Ritesh K. Baboota, Ulf Smith, Stephanie Heasman
Publikováno v:
PLoS ONE, Vol 16, Iss 2, p e0247300 (2021)
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
PLoS ONE
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
PLoS ONE
Objective Gremlin 1 (GREM1) is a secreted BMP2/4 inhibitor which regulates commitment and differentiation of human adipose precursor cells and prevents the browning effect of BMP4. GREM1 is an insulin antagonist and serum levels are high in type 2 di
Autor:
Anna Lindblom, Andrea Ahnmark, Matthew J. Harms, Stefanie Maurer, Tobias Kroon, Laurianne Bonnet, Daniel Nilsson, Victoria Osinski, Jeremie Boucher, Ida Alexandersson, Peter Gennemark, Gavin O'Mahony, Coleen A. McNamara
Publikováno v:
Molecular Metabolism
Molecular Metabolism, Vol 36, Iss, Pp-(2020)
Molecular Metabolism, Vol 36, Iss, Pp-(2020)
Objective Peroxisome proliferator-activated receptors (PPARs) are key transcription factors that regulate adipose development and function, and the conversion of white into brown-like adipocytes. Here we investigated whether PPARα and PPARγ activat
Autor:
Jean-Charles Martin, Laurianne Bonnet, Charlène Couturier, Marielle Margier, Emmanuelle Reboul, Jean-François Landrier, Ljubica Svilar, Catherine Defoort
Publikováno v:
Nutrients
Volume 11
Issue 9
Nutrients, MDPI, 2019, 11 (9), pp.1977. ⟨10.3390/nu11091977⟩
Nutrients 9 (11), 1977. (2019)
Nutrients, Vol 11, Iss 9, p 1977 (2019)
Nutrients, 2019, 11 (9), pp.1977. ⟨10.3390/nu11091977⟩
Volume 11
Issue 9
Nutrients, MDPI, 2019, 11 (9), pp.1977. ⟨10.3390/nu11091977⟩
Nutrients 9 (11), 1977. (2019)
Nutrients, Vol 11, Iss 9, p 1977 (2019)
Nutrients, 2019, 11 (9), pp.1977. ⟨10.3390/nu11091977⟩
Vitamin D metabolism is actively modulated in adipose tissue during obesity. To better investigate this process, we develop a specific LC-HRMS/MS method that can simultaneously quantify three vitamin D metabolites, i.e., cholecalciferol, 25-hydroxyvi
Autor:
Shahram, Hedjazifar, Roxana, Khatib Shahidi, Ann, Hammarstedt, Laurianne, Bonnet, Christopher, Church, Jeremie, Boucher, Matthias, Blüher, Ulf, Smith
Publikováno v:
Diabetes. 69(3)
The BMP2/4 antagonist and novel adipokine Gremlin 1 is highly expressed in human adipose cells and increased in hypertrophic obesity. As a secreted antagonist, it inhibits the effect of BMP2/4 on adipose precursor cell commitment/differentiation. We