Distinct Waves from the Hemogenic Endothelium Give Rise to Layered Lymphoid Tissue Inducer Cell Ontogeny

Autor: Milesa Simic, Iris Manosalva, Lionel Spinelli, Rebecca Gentek, Raheleh R. Shayan, Carole Siret, Mathilde Girard-Madoux, Shuaiwei Wang, Lauriane de Fabritus, Janneke Verschoor, Yann M. Kerdiles, Marc Bajenoff, Ralf Stumm, Rachel Golub, Serge A. van de Pavert

Publikováno v: Cell Reports, Vol 32, Iss 6, Pp 108004- (2020)

Summary: During embryogenesis, lymphoid tissue inducer (LTi) cells are essential for lymph node organogenesis. These cells are part of the innate lymphoid cell (ILC) family. Although their earliest embryonic hematopoietic origin is unclear, other inn

Externí odkaz: https://doaj.org/article/976572a732984708aeedd98df1083eeb

Attenuation of tick-borne encephalitis virus using large-scale random codon re-encoding.

Autor: Lauriane de Fabritus, Antoine Nougairède, Fabien Aubry, Ernest A Gould, Xavier de Lamballerie

Publikováno v: PLoS Pathogens, Vol 11, Iss 3, p e1004738 (2015)

Large-scale codon re-encoding (i.e. introduction of a large number of synonymous mutations) is a novel method of generating attenuated viruses. Here, it was applied to the pathogenic flavivirus, tick-borne encephalitis virus (TBEV) which causes febri

Externí odkaz: https://doaj.org/article/53918eccd20b4bb19c54b8807ad64071

Random codon re-encoding induces stable reduction of replicative fitness of Chikungunya virus in primate and mosquito cells.

Autor: Antoine Nougairede, Lauriane De Fabritus, Fabien Aubry, Ernest A Gould, Edward C Holmes, Xavier de Lamballerie

Publikováno v: PLoS Pathogens, Vol 9, Iss 2, p e1003172 (2013)

Large-scale codon re-encoding represents a powerful method of attenuating viruses to generate safe and cost-effective vaccines. In contrast to specific approaches of codon re-encoding which modify genome-scale properties, we evaluated the effects of

Externí odkaz: https://doaj.org/article/dda0d2b365ca48178662fbd1061f7891

Distinct Waves from the Hemogenic Endothelium Give Rise to Layered Lymphoid Tissue Inducer Cell Ontogeny

Autor: Mathilde J. H. Girard-Madoux, Yann M. Kerdiles, Rebecca Gentek, Lionel Spinelli, Raheleh R. Shayan, Carole Siret, Milesa Simic, Rachel Golub, Janneke Verschoor, Marc Bajénoff, Serge A. van de Pavert, Lauriane de Fabritus, Ralf Stumm, Iris Manosalva, Shuaiwei Wang

Publikováno v: Cell Reports
Cell Reports, Elsevier Inc, 2020, 32 (6), pp.108004. ⟨10.1016/j.celrep.2020.108004⟩
Simic, M, Manosalva, I, Spinelli, L, Gentek, R, Shayan, R R, Siret, C, Girard-Madoux, M, Wang, S, de Fabritus, L, Verschoor, J, Kerdiles, Y M, Bajenoff, M, Stumm, R, Golub, R & van de Pavert, S A 2020, ' Distinct Waves from the Hemogenic Endothelium Give Rise to Layered Lymphoid Tissue Inducer Cell Ontogeny ', Cell Reports, vol. 32, no. 6, pp. 108004 . https://doi.org/10.1016/j.celrep.2020.108004
Cell Reports, 2020, 32 (6), pp.108004. ⟨10.1016/j.celrep.2020.108004⟩
Cell Reports, Vol 32, Iss 6, Pp 108004-(2020)

International audience; During embryogenesis, lymphoid tissue inducer (LTi) cells are essential for lymph node organogenesis. These cells are part of the innate lymphoid cell (ILC) family. Although their earliest embryonic hematopoietic origin is unc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72c03b9e2806870311361249322bd8af
https://pubmed.ncbi.nlm.nih.gov/32783932

Single-stranded positive-sense RNA viruses generated in days using infectious subgenomic amplicons

Autor: Gilles Querat, Antoine Nougairède, Lauriane de Fabritus, Fabien Aubry, Ernest A. Gould, Xavier de Lamballerie

Publikováno v: The Journal of General Virology

Reverse genetics is a key methodology for producing genetically modified RNA viruses and deciphering cellular and viral biological properties, but methods based on the preparation of plasmid-based complete viral genomes are laborious and unpredictabl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::367ac11464373ff05a3c43ea3dba9430
https://pubmed.ncbi.nlm.nih.gov/25053561