Moderate decline in select synaptic markers in the prefrontal cortex (BA9) of patients with Alzheimer’s disease at various cognitive stages

Autor: Odile Poirel, Sébastien Mella, Catherine Videau, Lauriane Ramet, Maria Antonietta Davoli, Etienne Herzog, Pavel Katsel, Naguib Mechawar, Vahram Haroutunian, Jacques Epelbaum, Stéphanie Daumas, Salah El Mestikawy

Publikováno v: Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)

Abstract Synaptic loss, plaques and neurofibrillary tangles are viewed as hallmarks of Alzheimer’s disease (AD). This study investigated synaptic markers in neocortical Brodmann area 9 (BA9) samples from 171 subjects with and without AD at differen

Externí odkaz: https://doaj.org/article/c7b90a287ba34fcc92a652b92c9be045

Intestinal infection triggers Parkinson’s disease-like symptoms in Pink1−/− mice

Autor: Romain Cayrol, Diana Matheoud, Samantha Gruenheid, Marie-Josée Bourque, Annie Laplante, Michel Desjardins, Lei Zhu, Heidi M. McBride, Charles Ducrot, Anna-Maija Penttinen, Lauriane Ramet, Aurore Voisin, Ahmed M. Fahmy, Armelle Le Campion, Tyler Cannon, Louis-Eric Trudeau

Publikováno v: Nature. 571:565-569

Parkinson’s disease is a neurodegenerative disorder with motor symptoms linked to the loss of dopaminergic neurons in the substantia nigra compacta. Although the mechanisms that trigger the loss of dopaminergic neurons are unclear, mitochondrial dy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::de7db0a45e637ace367c415ab03c4606
https://doi.org/10.1038/s41586-019-1405-y

Magnesium Sulfate Prevents Neurochemical and Long-Term Behavioral Consequences of Neonatal Excitotoxic Lesions: Comparison Between Male and Female Mice

Autor: Lauriane Ramet, Cathy Gomila, Bruno J. Gonzalez, Jérôme Ausseil, Philippe Leroux, Ismaël Daher, Bérénice Le Dieu-Lugon, Vincent Roy, Isabelle Leroux-Nicollet, Matthieu Jean Alexandre Lecuyer, Nathalie Dourmap, Salah El Mestikawy, Stéphanie Daumas, Stéphane Marret, Carine Cleren

Publikováno v: Journal of Neuropathology and Experimental Neurology
Journal of Neuropathology and Experimental Neurology, Lippincott, Williams & Wilkins, 2017, 76 (10), pp.883-897. ⟨10.1093/jnen/nlx073⟩
Journal of Neuropathology and Experimental Neurology, 2017, 76 (10), pp.883-897. ⟨10.1093/jnen/nlx073⟩
BASE-Bielefeld Academic Search Engine

Magnesium sulfate (MgSO4) administration to mothers at risk of preterm delivery is proposed as a neuroprotective strategy against neurological alterations such as cerebral palsy in newborns. However, long-term beneficial or adverse effects of MgSO4 a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00cf2d138cf164645073bcb97f6b7d44
https://hal.archives-ouvertes.fr/hal-01662388

Characterization of a Human Point Mutation of VGLUT3 (p.A211V) in the Rodent Brain Suggests a Nonuniform Distribution of the Transporter in Synaptic Vesicles

Autor: Salah El Mestikawy, Stéphanie De Gois, Stéphanie Daumas, Louis-Eric Trudeau, Lauriane Ramet, Tiphaine Bersot, Christian Rosenmund, Diana Yae Sakae, Johannes Zimmermann, Nina Mansouri-Guilani, Odile Poirel, Katlin Silm, Véronique Bernard, Marie-Josée Bourque, Nicolas Pietrancosta

Publikováno v: Journal of Neuroscience
Journal of Neuroscience, 2017, 37 (15), pp.4181-4199. ⟨10.1523/JNEUROSCI.0282-16.2017⟩
Journal of Neuroscience, Society for Neuroscience, 2017, 37 (15), pp.4181-4199. ⟨10.1523/jneurosci.0282-16.2017⟩
Journal of Neuroscience, Society for Neuroscience, 2017, 37 (15), pp.4181-4199. ⟨10.1523/JNEUROSCI.0282-16.2017⟩
Journal of Neuroscience, Society for Neuroscience, 2017, 37 (15), pp.4181-4199. 〈10.1523/JNEUROSCI.0282-16.2017〉

The atypical vesicular glutamate transporter type 3 (VGLUT3) is expressed by subpopulations of neurons using acetylcholine, GABA, or serotonin as neurotransmitters. In addition, VGLUT3 is expressed in the inner hair cells of the auditory system. A mu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6672a0d91050528714368943f6c8e264
https://europepmc.org/articles/PMC6596587/

Differential expression of VGLUT3 in laboratory mouse strains: Impact on drug-induced hyperlocomotion and anxiety-related behaviors

Autor: Stéphane Jamain, Lauriane Ramet, Diana Yae Sakae, Odile Poirel, Salah El Mestikawy, Stéphanie Daumas, Annabelle Henrion

Publikováno v: Genes, Brain and Behavior
Genes, Brain and Behavior, Wiley, 2019, 18 (3), pp.e12528. ⟨10.1111/gbb.12528⟩

International audience; The atypical vesicular glutamate transporter VGLUT3 is present in subpopulations of GABAergic interneurons in the cortex and the hippocampus, in subgroups of serotoninergic neurons in raphe nuclei, and in cholinergic interneur

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2265e687fb96e67f789e0bbc5e4c4e09
https://doi.org/10.1111/gbb.12528