Výsledky vyhledávání - "Lauriane Benoist"

P2Y11 Agonism Prevents Hypoxia/Reoxygenation- and Angiotensin II-Induced Vascular Dysfunction and Intimal Hyperplasia Development

Autor: Stéphanie Chadet, Marie Piollet, Claudie Gabillard-Lefort, Fabrice Ivanes, Oana-Maria Aburel, Lauriane Benoist, Denis Angoulvant, Danina-Mirela Muntean, Adrian Sturza

Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 855, p 855 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 2

Vascular dysfunction in cardiovascular diseases includes vasomotor response impairments, endothelial cells (ECs) activation, and smooth muscle cells (SMCs) proliferation and migration to the intima. This results in intimal hyperplasia and vessel fail

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfc7f49014c876a048c909645896ddfc
https://doi.org/10.3390/ijms22020855

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Stimulation of murine P2Y11-like purinoreceptor protects against hypoxia/reoxygenation injury and decreases heart graft rejection lesions

Autor: Stéphanie Chadet, Gaëlle Fromont, Denis Angoulvant, Lauriane Benoist, Fabrice Ivanes, Elodie Miquelestorena-Standley, Thierry Bourguignon

Publikováno v: Journal of Thoracic and Cardiovascular Surgery
Journal of Thoracic and Cardiovascular Surgery, Elsevier, 2019, 158, pp.780-790.e1. ⟨10.1016/j.jtcvs.2018.12.014⟩

Objective Myocardial ischemia reperfusion is a major cause of cell injury during cardiac transplantation and is responsible for increased graft rejection. Several in vitro studies demonstrated the protective effect of P2Y11-like purinoreceptor stimul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cac05bfcac5ab71b8124b0aebbc92fda
https://pubmed.ncbi.nlm.nih.gov/30685173

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Stimulation of P2Y11 receptor modulates cardiac fibroblasts secretome toward immunomodulatory and protective roles after Hypoxia/Reoxygenation injury

Autor: Stéphanie Chadet, Lauriane Benoist, Marie Piollet, Dominique Babuty, Claudie Lefort, Fabrice Ivanes, Audrey Heraud, Christophe Baron, Denis Angoulvant

Publikováno v: Journal of molecular and cellular cardiology. 121

Cardiac fibroblasts are important regulators of myocardial structure and function. Their implications in pathological processes such as Ischemia/Reperfusion are well characterized. Cardiac fibroblasts respond to stress by excessive proliferation and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a40c99f80e0322fc06792df1a8c190b
https://pubmed.ncbi.nlm.nih.gov/30031814

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Stimulation of P2Y11 receptor modulates cardiac fibroblasts secretome towards immunomodulatory and protective roles after simulated Ischemia/Reperfusion injury

Autor: Dominique Babuty, Marie Piollet, Denis Angoulvant, Fabrice Ivanes, Stéphanie Chadet, Claudie Lefort, Audrey Heraud, Lauriane Benoist, Christophe Baron, Thierry Bourguignon

Publikováno v: Archives of Cardiovascular Diseases Supplements. 10:183-184

Introduction Ischemia/Reperfusion (I/R) injuries are involved in many myocardial pathologic processes. Cardiac fibroblasts (CF) respond to this stress by excessive proliferation and secretion of soluble factors, e.g. ATP, leading to purinergic recept

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2802a895515636ad0a001b8795c23ec0
https://doi.org/10.1016/j.acvdsp.2018.02.018

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IMPROVEMENT OF VASCULAR RESPONSE TO ISCHEMIA/REPERFUSION INJURY: ROLE OF THE P2Y11 PURINERGIC RECEPTOR

Autor: Claudie Lefort, Danina Muntean, Denis Angoulvant, Adrian Sturza, Lauriane Benoist, Fabrice Ivanes, Oana Duicu, Marie Piollet, Stéphanie Chadet

Publikováno v: Journal of the American College of Cardiology. 73:2121

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::26ca133209d6b924102b5e1221361296
https://doi.org/10.1016/s0735-1097(19)32727-5

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0408 : Stimulation of P2Y11 purinergic receptor reduces rejection lesions and increases survival time of heart allograft in a mouse model

Autor: Christophe Jayle, Thierry Bourguignon, Michel Aupart, Fabrice Ivanes, Stéphanie Chadet, Denis Angoulvant, Roseline Guibon, Clémence Klipfel-Lhommet, Claudie Lefort, Gaëlle Fromont, Lauriane Benoist

Publikováno v: Archives of Cardiovascular Diseases Supplements. 8(3)

Introduction Graft rejection is the main complication after heart transplantation. We recently demonstrated in vitro that the stimulation of P2Y11 receptor reduces ischemia/reperfusion lesions in human cardiomyocytes and is responsible for dendritic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2291ac09250f42f6b40f4f1172a0bf19

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Hypoxia/Reoxygenation Inhibits P2Y11 Receptor Expression and Its Immunosuppressive Activity in Human Dendritic Cells

Autor: Fabrice Ivanes, Christophe Baron, Florence Velge-Roussel, Roseline Guibon, Lauriane Benoist, Stéphanie Chadet, Dominique Babuty, Denis Angoulvant, Charlotte Salmon-Gandonnière, Sébastien Roger

Publikováno v: Journal of Immunology
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2015, 195 (2), pp.651-660. ⟨10.4049/jimmunol.1500197⟩
Journal of Immunology, 2015, 195 (2), pp.651-660. ⟨10.4049/jimmunol.1500197⟩

High concentrations of extracellular ATP (eATP) resulting from cell damage may be found during an ischemia/reperfusion (I/R) episode at the site of injury. eATP activates purinergic receptors in dendritic cells (DCs) and may inhibit inflammation. Thi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edb8c43857c707c2a7db4529540131af
https://pubmed.ncbi.nlm.nih.gov/26078273

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