Zobrazeno 1 - 10
of 384
pro vyhledávání: '"Laurian Vlase"'
Autor:
Oana Baldasici, Olga Soritau, Andrei Roman, Carmen Lisencu, Simona Visan, Laura Maja, Bogdan Pop, Bogdan Fetica, Andrei Cismaru, Laurian Vlase, Loredana Balacescu, Ovidiu Balacescu, Aman Russom, Oana Tudoran
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Background Cancer stem-like cells (CSCs) have been extensively researched as the primary drivers of therapy resistance and tumor relapse in patients with breast cancer. However, due to lack of specific molecular markers, increased phenotypic
Externí odkaz:
https://doaj.org/article/0078d5c4c5e44c268eece64cafeb7586
Autor:
Ligia-Ancuța Hui, Constantin Bodolea, Adina Popa, Ana-Maria Vlase, Elisabeta Ioana Hirișcău, Laurian Vlase
Publikováno v:
Antibiotics, Vol 13, Iss 10, p 961 (2024)
Background: Linezolid has been found to have considerable interindividual variability, especially in critically ill patients, which can lead to suboptimal plasma concentration. To overcome this shortcoming, several solutions have been proposed. These
Externí odkaz:
https://doaj.org/article/4721933d00584bfcbb685c9e7d94e92a
Autor:
Octavia Maria TAMAS-KRUMPE, Rodica MĂRGĂOAN, Mihaiela CORNEA-CIPCIGAN, Otilia BOBIŞ, Victorița BONTA, Adela MOISE, Adela PINTEA, Cornelia DOŞTEŢAN, Laurian VLASE, Laurenţ OGNEAN
Publikováno v:
Bulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca: Food Science and Technology, Vol 81, Iss 1 (2024)
Bee products and natural oils are appreciated due to their beneficial effects on health, which are strongly related to several pharmacological and biological activities. The present study aimed to assess the bioactive potential of two bee products wi
Externí odkaz:
https://doaj.org/article/ffa3ea491892420990b3f1bbf65dd570
Autor:
Alexandra Cătălina Cornea, Gabriel Marc, Ioana Ionuț, Cristina Moldovan, Ionel Fizeșan, Andreea-Elena Petru, Ionuț-Valentin Creștin, Adrian Pîrnău, Laurian Vlase, Ovidiu Oniga
Publikováno v:
Antioxidants, Vol 13, Iss 8, p 937 (2024)
A series of thiazolyl–catechol compounds with antioxidant and cytotoxic activities were synthesized by a Hantzsch heterocyclization, using diverse thioamides as the thiocarbonyl component and 4-chloroacetyl-catechol as haloketone. These compounds w
Externí odkaz:
https://doaj.org/article/3f67cc5c0618452181ed2e64bfdc1b12
Autor:
Elena Cristina Scutarașu, Răzvan George Niță, Laurian Vlase, Cătălin Ioan Zamfir, Bogdan Ionel Cioroiu, Lucia Cintia Colibaba, Dana Muntean, Camelia Elena Luchian, Ana Maria Vlase, Valeriu Cotea
Publikováno v:
Antioxidants, Vol 13, Iss 8, p 916 (2024)
Melatonin is commonly found in various fruits, juices, and some fermented beverages. Its concentration in wine is influenced by soil properties, climatic factors, and yeast activity. Even if it is found in fermented beverages in relatively low propor
Externí odkaz:
https://doaj.org/article/167a8637e7024a428cccb8e8dac360cc
Autor:
Daniela Benedec, Ilioara Oniga, Daniela Hanganu, Ana-Maria Vlase, Irina Ielciu, Gianina Crișan, Nicodim Fiţ, Mihaela Niculae, Timea Bab, Emoke Pall, Laurian Vlase
Publikováno v:
Plants, Vol 13, Iss 13, p 1790 (2024)
The species of the genus Euphrasia present important medicinal potential according to their traditional uses. However, few studies aim to sustain this fact by scientific evidence. The present study aimed to explore the phytochemical profile and inves
Externí odkaz:
https://doaj.org/article/3550b4e73bbf40d6a407533780b94153
Autor:
Raluca Pele, Gabriel Marc, Cristina Mogoșan, Anamaria Apan, Ioana Ionuț, Brîndușa Tiperciuc, Cristina Moldovan, Cătălin Araniciu, Ilioara Oniga, Adrian Pîrnău, Laurian Vlase, Ovidiu Oniga
Publikováno v:
Molecules, Vol 29, Iss 9, p 1951 (2024)
Two series, “a” and “b”, each consisting of nine chemical compounds, with 2,3-disubstituted quinazolin-4(3H)-one scaffold, were synthesized and evaluated for their anticonvulsant activity. They were investigated as dual potential positive all
Externí odkaz:
https://doaj.org/article/cc3af2d38c7d4f19afcf310d80a07171
Autor:
Alexandru Șandor, Ionel Fizeșan, Ioana Ionuț, Gabriel Marc, Cristina Moldovan, Ilioara Oniga, Adrian Pîrnău, Laurian Vlase, Andreea-Elena Petru, Ioana Macasoi, Ovidiu Oniga
Publikováno v:
Biomolecules, Vol 14, Iss 2, p 218 (2024)
Considering the pivotal role of angiogenesis in solid tumor progression, we developed a novel series of quinazoline–thiazole hybrids (SA01–SA07) as antiproliferative and anti-angiogenic agents. Four out of the seven compounds displayed superior a
Externí odkaz:
https://doaj.org/article/d0ba008f63234d54bc3478c157a527cb
Autor:
Carmen Elena Pop, Ana Coste, Ana-Maria Vlase, Constantin Deliu, Mircea Tămaș, Tibor Casian, Laurian Vlase
Publikováno v:
Life, Vol 14, Iss 1, p 84 (2024)
This study aimed to investigate the biotransformation capabilities of a hydroquinone-tolerant Digitalis purpurea cell line (DpHQ) for bioconverting hydroquinone (HQ) into arbutin, a compound with significant therapeutic and cosmetic applications. The
Externí odkaz:
https://doaj.org/article/2b7b8c568b2f4c6788b41fd88eb8b2f5
Autor:
Alexandra-Denisa Semenescu, Elena-Alina Moacă, Andrada Iftode, Cristina-Adriana Dehelean, Diana-Simona Tchiakpe-Antal, Laurian Vlase, Slavita Rotunjanu, Delia Muntean, Sorin Dan Chiriac, Raul Chioibaş
Publikováno v:
Life, Vol 14, Iss 1, p 112 (2024)
The biological activity of Galium verum herba was exerted on various tumor cell lines with incredible results, but their potential effect on malignant melanoma has not been established yet. Therefore, the current study was structured in two direction
Externí odkaz:
https://doaj.org/article/bedfd1e5e68c429b8beb512f394dba35