Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Lauri J, Lehto"'
Autor:
Lin Wu, Antonietta Canna, Omar Narvaez, Jun Ma, Sheng Sang, Lauri J. Lehto, Alejandra Sierra, Heikki Tanila, Yuan Zhang, Olli Gröhn, Walter C. Low, Pavel Filip, Silvia Mangia, Shalom Michaeli
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract The recently introduced orientation selective deep brain stimulation (OS-DBS) technique freely controls the direction of the electric field’s spatial gradient by using multiple contacts with independent current sources within a multielectr
Externí odkaz:
https://doaj.org/article/5372bd97c5e046e1889ab47e58c0b0a2
Autor:
Antonietta Canna, Lauri J. Lehto, Lin Wu, Sheng Sang, Hanne Laakso, Jun Ma, Pavel Filip, Yuan Zhang, Olli Gröhn, Fabrizio Esposito, Clark C. Chen, Igor Lavrov, Shalom Michaeli, Silvia Mangia
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Epidural spinal cord stimulation (ESCS) is widely used for chronic pain treatment, and is also a promising tool for restoring motor function after spinal cord injury. Despite significant positive impact of ESCS, currently available protocols
Externí odkaz:
https://doaj.org/article/b04de9cae18847f2a2d23a54939206e5
Autor:
Julia P. Slopsema, Antonietta Canna, Michelle Uchenik, Lauri J. Lehto, Jordan Krieg, Lucius Wilmerding, Dee M. Koski, Naoharu Kobayashi, Joan Dao, Madeline Blumenfeld, Pavel Filip, Hoon-Ki Min, Silvia Mangia, Matthew D. Johnson, Shalom Michaeli
Publikováno v:
NeuroImage, Vol 224, Iss , Pp 117357- (2021)
Functional MRI (fMRI) has become an important tool for probing network-level effects of deep brain stimulation (DBS). Previous DBS-fMRI studies have shown that electrical stimulation of the ventrolateral (VL) thalamus can modulate sensorimotor cortic
Externí odkaz:
https://doaj.org/article/60e71f28c93341de9deadaffd3a10c69
Autor:
Erwin A. van Vliet, Xavier Ekolle Ndode-Ekane, Lauri J. Lehto, Jan A. Gorter, Pedro Andrade, Eleonora Aronica, Olli Gröhn, Asla Pitkänen
Publikováno v:
Neurobiology of Disease, Vol 145, Iss , Pp 105080- (2020)
Background: Traumatic brain injury (TBI) causes 10–20% of acquired epilepsy, which typically develops within 2 years post-injury with poorly understood mechanisms. We investigated the location, severity, evolution and persistence of blood-brain bar
Externí odkaz:
https://doaj.org/article/6f3e4d520b1e414d9098b12b34618fa2
Autor:
Lauri J. Lehto, Antonietta Canna, Lin Wu, Alejandra Sierra, Ekaterina Zhurakovskaya, Jun Ma, Clairice Pearce, Maple Shaio, Pavel Filip, Matthew D. Johnson, Walter C. Low, Olli Gröhn, Heikki Tanila, Silvia Mangia, Shalom Michaeli
Publikováno v:
NeuroImage, Vol 213, Iss , Pp 116750- (2020)
Deep brain stimulation (DBS) has become an important tool in the management of a wide spectrum of diseases in neurology and psychiatry. Target selection is a vital aspect of DBS so that only the desired areas are stimulated. Segmented leads and curre
Externí odkaz:
https://doaj.org/article/d4f6e2da92a343e2ab0d2a292b9df869
Autor:
Jaakko Paasonen, Hanne Laakso, Tiina Pirttimäki, Petteri Stenroos, Raimo A. Salo, Ekaterina Zhurakovskaya, Lauri J. Lehto, Heikki Tanila, Michael Garwood, Shalom Michaeli, Djaudat Idiyatullin, Silvia Mangia, Olli Gröhn
Publikováno v:
NeuroImage, Vol 206, Iss , Pp 116338- (2020)
Functional magnetic resonance imaging (fMRI) studies in animal models provide invaluable information regarding normal and abnormal brain function, especially when combined with complementary stimulation and recording techniques. The echo planar imagi
Externí odkaz:
https://doaj.org/article/b6f52f864549463d8b46662113a927db
Autor:
Lauri J. Lehto, Pavel Filip, Hanne Laakso, Alejandra Sierra, Julia P. Slopsema, Matthew D. Johnson, Lynn E. Eberly, Walter C. Low, Olli Gröhn, Heikki Tanila, Silvia Mangia, Shalom Michaeli
Publikováno v:
Frontiers in Neuroscience, Vol 12 (2018)
Previous studies that focused on treating major depressive disorder with conventional deep brain stimulation (DBS) paradigms produced inconsistent results. In this proof-of-concept preclinical study in rats (n = 8), we used novel paradigms of orienta
Externí odkaz:
https://doaj.org/article/2559c433cbb84f0aaf272f8d8cf363f2
Autor:
Lauri J. Lehto, Aloma A. Albors, Alejandra Sierra, Laura Tolppanen, Lynn E. Eberly, Silvia Mangia, Antti Nurmi, Shalom Michaeli, Olli Gröhn
Publikováno v:
Frontiers in Neuroscience, Vol 11 (2017)
In this work a new MRI modality entitled Relaxation Along a Fictitious Field in the rotating frame of rank 4 (RAFF4) was evaluated in its ability to detect lower myelin content in lysophosphatidyl choline (LPC)-induced demyelinating lesions. The lesi
Externí odkaz:
https://doaj.org/article/fcdabd0a70854a6e944deec0db4fef0e
Autor:
Shalom Michaeli, Igor Lavrov, Jaakko Paasonen, Lauri J. Lehto, Antonietta Canna, Olli Gröhn, Hanne Laakso, Silvia Mangia, Raimo A. Salo
Publikováno v:
Magnetic Resonance in Medicine
Purpose: Electrical epidural spinal cord stimulation (SCS) is used as a treatment for chronic pain as well as to partially restore motor function after a spinal cord injury. Monitoring the spinal cord activity during SCS with fMRI could provide impor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::787a5bb5f5c4c1f75210233f8182aa8e
https://doi.org/10.1002/mrm.28844
https://doi.org/10.1002/mrm.28844
Autor:
Jun Ma, Clark C. Chen, Igor Lavrov, Shalom Michaeli, Lin Wu, Sheng Sang, Fabrizio Esposito, Lauri J. Lehto, Antonietta Canna, Olli Gröhn, Hanne Laakso, Silvia Mangia, Pavel Filip, Yuan Zhang
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports
Scientific Reports
Epidural spinal cord stimulation (ESCS) is widely used for chronic pain treatment, and is also a promising tool for restoring motor function after spinal cord injury. Despite significant positive impact of ESCS, currently available protocols provide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1611a6a813f9f7c21b5bd746aaec3bf
http://hdl.handle.net/11591/446753
http://hdl.handle.net/11591/446753
