Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Lauri D Aicher"'
Autor:
Martin T Ferris, David L Aylor, Daniel Bottomly, Alan C Whitmore, Lauri D Aicher, Timothy A Bell, Birgit Bradel-Tretheway, Janine T Bryan, Ryan J Buus, Lisa E Gralinski, Bart L Haagmans, Leonard McMillan, Darla R Miller, Elizabeth Rosenzweig, William Valdar, Jeremy Wang, Gary A Churchill, David W Threadgill, Shannon K McWeeney, Michael G Katze, Fernando Pardo-Manuel de Villena, Ralph S Baric, Mark T Heise
Publikováno v:
PLoS Pathogens, Vol 9, Iss 2, p e1003196 (2013)
Genetic variation contributes to host responses and outcomes following infection by influenza A virus or other viral infections. Yet narrow windows of disease symptoms and confounding environmental factors have made it difficult to identify polymorph
Externí odkaz:
https://doaj.org/article/7b65541d5dda41df84e78d9a797b012a
Autor:
Cristian Cillóniz, Kyoko Shinya, Xinxia Peng, Marcus J Korth, Sean C Proll, Lauri D Aicher, Victoria S Carter, Jean H Chang, Darwyn Kobasa, Friedericke Feldmann, James E Strong, Heinz Feldmann, Yoshihiro Kawaoka, Michael G Katze
Publikováno v:
PLoS Pathogens, Vol 5, Iss 10, p e1000604 (2009)
The enormous toll on human life during the 1918-1919 Spanish influenza pandemic is a constant reminder of the potential lethality of influenza viruses. With the declaration by the World Health Organization of a new H1N1 influenza virus pandemic, and
Externí odkaz:
https://doaj.org/article/69146b6be9d7436f83aa9050f9bb54c6
Autor:
Robert H.I. Andtbacka, Yan Wang, Robert H. Pierce, Jean S. Campbell, Melinda Yushak, Mohammed Milhem, Merrick Ross, Katie Niland, Robert D. Arbeit, Sudha Parasuraman, Kris Bickley, Cecilia CS Yeung, Lauri D. Aicher, Kimberly S. Smythe, Lu Gan
Publikováno v:
Cancer Research Communications. 2:904-913
Purpose: Mavorixafor is an oral, selective inhibitor of the CXCR4 chemokine receptor that modulates immune cell trafficking. A biomarker-driven phase Ib study (NCT02823405) was conducted in 16 patients with melanoma to investigate the hypothesis that
Autor:
Lu Gan, Kimberly S. Smythe, Lauri D. Aicher, Cecilia CS Yeung, Kris Bickley, Sudha Parasuraman, Robert D. Arbeit, Katie Niland, Merrick Ross, Mohammed Milhem, Melinda Yushak, Jean S. Campbell, Robert H. Pierce, Yan Wang, Robert H.I. Andtbacka
Antibody panels used for mIF analyses.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d2a1af716f0bd76c6e9fa7b043dbd23
https://doi.org/10.1158/2767-9764.22545773.v1
https://doi.org/10.1158/2767-9764.22545773.v1
Autor:
Lu Gan, Kimberly S. Smythe, Lauri D. Aicher, Cecilia CS Yeung, Kris Bickley, Sudha Parasuraman, Robert D. Arbeit, Katie Niland, Merrick Ross, Mohammed Milhem, Melinda Yushak, Jean S. Campbell, Robert H. Pierce, Yan Wang, Robert H.I. Andtbacka
Serum cytokine and chemokine changes at the end of the 3-week monotherapy period compared to baseline.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c5098d1822b7b01f14f78eb4c3a72ba
https://doi.org/10.1158/2767-9764.22545770.v1
https://doi.org/10.1158/2767-9764.22545770.v1
Autor:
Lu Gan, Kimberly S. Smythe, Lauri D. Aicher, Cecilia CS Yeung, Kris Bickley, Sudha Parasuraman, Robert D. Arbeit, Katie Niland, Merrick Ross, Mohammed Milhem, Melinda Yushak, Jean S. Campbell, Robert H. Pierce, Yan Wang, Robert H.I. Andtbacka
Purpose:Mavorixafor is an oral, selective inhibitor of the CXCR4 chemokine receptor that modulates immune cell trafficking. A biomarker-driven phase Ib study (NCT02823405) was conducted in 16 patients with melanoma to investigate the hypothesis that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::412d1a88bdb6c622134f34d6dd3e332d
https://doi.org/10.1158/2767-9764.c.6551033.v1
https://doi.org/10.1158/2767-9764.c.6551033.v1
Autor:
Lu Gan, Kimberly S. Smythe, Lauri D. Aicher, Cecilia CS Yeung, Kris Bickley, Sudha Parasuraman, Robert D. Arbeit, Katie Niland, Merrick Ross, Mohammed Milhem, Melinda Yushak, Jean S. Campbell, Robert H. Pierce, Yan Wang, Robert H.I. Andtbacka
Shared TCR TIL sequences taken from tumor biopsy of patient #5 at various timepoints.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00a79627298ef8dc5b78551cef478a86
https://doi.org/10.1158/2767-9764.22545779.v1
https://doi.org/10.1158/2767-9764.22545779.v1
Autor:
Lu Gan, Kimberly S. Smythe, Lauri D. Aicher, Cecilia CS Yeung, Kris Bickley, Sudha Parasuraman, Robert D. Arbeit, Katie Niland, Merrick Ross, Mohammed Milhem, Melinda Yushak, Jean S. Campbell, Robert H. Pierce, Yan Wang, Robert H.I. Andtbacka
Depiction of T cell clone mobilization from peripheral blood to melanoma site on day 1 and at EOT.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e18f10426dc9934d3fce1d6e4d95278
https://doi.org/10.1158/2767-9764.22545776
https://doi.org/10.1158/2767-9764.22545776
Autor:
Martin T. Ferris, Mark T. Heise, Lisa E. Gralinski, Alan C. Whitmore, Elizabeth Rosenzweig, Janine T. Bryan, Daniel Bottomly, David W. Threadgill, Ralph S. Baric, Shannon K. McWeeney, Bart L. Haagmans, Fernando Pardo-Manuel de Villena, Michael G. Katze, David L. Aylor, Birgit G. Bradel-Tretheway, Lauri D. Aicher
Publikováno v:
G3-Genes Genomes Genetics, 2(2), 213-221. Genetics Society of America
G3: Genes|Genomes|Genetics
G3: Genes|Genomes|Genetics
Outbreaks of influenza occur on a yearly basis, causing a wide range of symptoms across the human population. Although evidence exists that the host response to influenza infection is influenced by genetic differences in the host, this has not been s
Autor:
Jean H. Chang, Sophia Jeng, Shannon K. McWeeney, Amy L. Ellis, Chengjun Li, Yasuko Hatta, Sean Proll, Katrina M. Waters, Armand Bankhead, Gabriele Neumann, G. Lynn Law, Michael G. Katze, Yoshihiro Kawaoka, Amie J. Eisfeld, Lauri D. Aicher
Publikováno v:
Journal of Virology. 85:10955-10967
During the last decade, more than half of humans infected with highly pathogenic avian influenza (HPAI) H5N1 viruses have died, yet virus-induced host signaling has yet to be clearly elucidated. Airway epithelia are known to produce inflammatory medi