Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Lauretta LeVoci"'
Autor:
Georgy Hartmann, Robert O. Blaustein, Suoyu Xu, Sheng-Ping Wang, Min Lu, Lauretta LeVoci, Ying Chen, Mihajlo L. Krsmanovic, Douglas G. Johns, Thomas Bateman
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 47(3)
Anacetrapib is an inhibitor of cholesteryl ester transfer protein (CETP), associated with reduction in LDL cholesterol and increase in HDL cholesterol in hypercholesterolemic patients. Anacetrapib was not taken forward into filing/registration as a n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adbe947b8caa1ba453241c4f212b2891
https://pubmed.ncbi.nlm.nih.gov/30567880
https://pubmed.ncbi.nlm.nih.gov/30567880
Autor:
Karen Gagen, Ying Chen, Andrea M. Peier, Anka G. Ehrhardt, Paul A. Fischer, Lauretta LeVoci, Dan Xie, Seongah Han, Douglas G. Johns, Sheng-Ping Wang, Timothy S. Fisher
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1831:825-833
Cholesteryl ester transfer protein (CETP) is a target of therapeutic intervention for coronary heart disease. Anacetrapib, a potent inhibitor of CETP, has been shown to reduce LDL-cholesterol by 40% and increase HDL-cholesterol by 140% in patients, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bef88903384ced91e206711ac8a8bfb1
https://doi.org/10.1016/j.bbalip.2012.12.008
https://doi.org/10.1016/j.bbalip.2012.12.008
Publikováno v:
Hepatology. 46:1971-1978
Recent studies have shown a pluripotential nature of stem cells that were previously thought to be committed to specific lineages. HBC-3 cells are a clonal fetal murine hepatoblast cell line derived from an e9.5 murine embryo, and these cells can be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebe587bcf86406ffef8c9d1ec332e6f2
https://doi.org/10.1002/hep.21894
https://doi.org/10.1002/hep.21894
Publikováno v:
Mechanisms of Development. 123:177-194
Bile duct morphogenesis involves sequential induction of biliary specific gene expression, bilayer generation, cell proliferation, remodeling and apoptosis. HBC-3 cells are a model system to study differentiation of hepatoblasts along the hepatocytic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d4248e27003b72cac7645222d1687a9
https://doi.org/10.1016/j.mod.2005.10.003
https://doi.org/10.1016/j.mod.2005.10.003
Autor:
Raquel Norel, Tatyana Tchaikovskaya, Leslie E. Rogler, Aldo Massimi, Lauretta LeVoci, Tammy Ader, Charles E. Rogler
Publikováno v:
Hepatology (Baltimore, Md.). 50(2)
Transforming growth factor-beta / bone morphogenetic protein (TGFβ/BMP) signaling has a gradient of effects on cell fate choice in the fetal mouse liver. The molecular mechanism to understand why adjacent cells develop into bile ducts or grow active
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b46bcff6192b824b5454e1faf45a2214
https://pubmed.ncbi.nlm.nih.gov/19582816
https://pubmed.ncbi.nlm.nih.gov/19582816
Autor:
Leslie E. Rogler, Tobias Goeser, Lauretta LeVoci, David A. Shafritz, Dirk Nierhoff, Sigrid Schulte
Publikováno v:
Hepatology (Baltimore, Md.). 46(2)
Isolation of hepatic stem cells from the adult liver (AL) has not yet been achieved due to the lack of specific cell surface markers. To identify new surface markers for hepatic stem cells, we analyzed differences in the gene expression profile of em
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::778433620ac9b37727e17e5846050a9e
https://pubmed.ncbi.nlm.nih.gov/17508344
https://pubmed.ncbi.nlm.nih.gov/17508344
Autor:
Josef Ekstein, Nicole R. Toto, Sylvia L. Anderson, Mary C. Donnelly, Berish Y. Rubin, Lauretta LeVoci, Erin M. Keefe
Publikováno v:
Human Genetics. 115
Nemaline myopathy (NM) is a neuromuscular disorder that is clinically diverse and can be attributed to mutations in any of several genes. The Ashkenazi Jewish population, which represents a relatively genetically homogeneous group, has an increased f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a09d0707a2db1e8897ce357d15d84dc
https://doi.org/10.1007/s00439-004-1140-8
https://doi.org/10.1007/s00439-004-1140-8