Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Laurenz de Cock"'
Autor:
Melissa Pille, John Avila, Guillem Sanchez Sanchez, Glenn Goetgeluk, Stijn De Munter, Hanne Jansen, Lore Billiet, Karin Weening, Haipeng Xue, Sarah Bonte, Joline Ingels, Laurenz De Cock, Eva Pascal, Lucas Deseins, Tessa Kerre, Tom Taghon, Georges Leclercq, David Vermijlen, Brian Davis, Bart Vandekerckhove
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The Wiskott–Aldrich syndrome (WAS) is an X-linked primary immune deficiency caused by a mutation in the WAS gene. This leads to altered or absent WAS protein (WASp) expression and function resulting in thrombocytopenia, eczema, recurrent infections
Externí odkaz:
https://doaj.org/article/8e328ea3407848819b605b95f452cf7f
Autor:
Sarah Bonte, Stijn de Munter, Lore Billiet, Glenn Goetgeluk, Joline Ingels, Hanne Jansen, Melissa Pille, Laurenz de Cock, Karin Weening, Tom Taghon, Georges Leclercq, Bart Vandekerckhove, Tessa Kerre
Publikováno v:
OncoImmunology, Vol 10, Iss 1 (2021)
T cell receptor (TCR)-redirected T cells target intracellular antigens such as Wilms’ tumor 1 (WT1), a tumor-associated antigen overexpressed in several malignancies, including acute myeloid leukemia (AML). For both chimeric antigen receptor (CAR)-
Externí odkaz:
https://doaj.org/article/b8d37350b35e4c9e9ca7c2af1a96b344
Autor:
Lore Billiet, Glenn Goetgeluk, Sarah Bonte, Stijn De Munter, Laurenz De Cock, Melissa Pille, Joline Ingels, Hanne Jansen, Karin Weening, Filip Van Nieuwerburgh, Tessa Kerre, Tom Taghon, Georges Leclercq, Bart Vandekerckhove
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 22, p 8785 (2020)
Human thymic CD8αα+ CD10+ PD-1+ αβ T cells selected through early agonist selection have been proposed as the putative thymic precursors of the human CD8αα+ intestinal intraepithelial lymphocytes (IELs). However, the progeny of these thymic pre
Externí odkaz:
https://doaj.org/article/f15cf268ed5b4742a78571f56d5abebd
Autor:
Stijn De Munter, Juliane Buhl, Laurenz De Cock, Alexander Van Parys, Willem Daneels, Eva Pascal, Lucas Deseins, Joline Ingels, Glenn Goetgeluk, Lore Billiet, Melissa Pille, Niels Vandamme, Jo Van Dorpe, Fritz Offner, Erik Depla, Jan Tavernier, Tessa Kerre, Jarno Drost, Bart Vandekerckhove
CD70 is an attractive target for chimeric antigen receptor (CAR) T cell therapy as treatment for both solid and liquid malignancies. However, functionality of CD70-specific CARs is only modest. Here, we optimized a CD70-specific VHH based CAR (nanoCA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e90292e5574b0d0e1648efcade88f4e
https://doi.org/10.1101/2023.01.22.523482
https://doi.org/10.1101/2023.01.22.523482
Autor:
Lore Billiet, Laurenz De Cock, Guillem Sanchez Sanchez, Rupert L. Mayer, Glenn Goetgeluk, Stijn De Munter, Melissa Pille, Joline Ingels, Hanne Jansen, Karin Weening, Eva Pascal, Killian Raes, Sarah Bonte, Tessa Kerre, Niels Vandamme, Ruth Seurinck, Jana Roels, Marieke Lavaert, Filip Van Nieuwerburgh, Georges Leclercq, Tom Taghon, Francis Impens, Björn Menten, David Vermijlen, Bart Vandekerckhove
Publikováno v:
JOURNAL OF EXPERIMENTAL MEDICINE
Billiet et al. identify the post-thymic progeny of the agonist-selected CD10(+) PD-1(+) precursors in humans based on shared characteristics of the T cell receptor repertoire and the transcriptome. This lineage represents a well-defined but heterogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3eb2709fc96a8b395ba17769f1460ee0
https://biblio.ugent.be/publication/01H32AFRDVK3SC2WQW4NA0DG5Z/file/01H32AGM1QN46XV5BFJWVGT2X3
https://biblio.ugent.be/publication/01H32AFRDVK3SC2WQW4NA0DG5Z/file/01H32AGM1QN46XV5BFJWVGT2X3
Autor:
Lore Billiet, Laurenz De Cock, Guillem Sanchez Sanchez, Rupert L. Mayer, Glenn Goetgeluk, Stijn De Munter, Melissa Pille, Joline Ingels, Hanne Jansen, Karin Weening, Eva Pascal, Killian Raes, Sarah Bonte, Tessa Kerre, Niels Vandamme, Ruth Seurinck, Jana Roels, Marieke Lavaert, Filip Van Nieuwerburgh, Georges Leclercq, Tom Taghon, Francis Impens, Björn Menten, David Vermijlen, Bart Vandekerckhhove
In the human thymus, a CD10+ PD-1+ TCRαβ+ differentiation pathway diverges from the conventional single positive T cell lineages at the early double positive stage. These cells are phenotypically and functionally similar to murine unconventional in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6aa90518c258da3c0d8b6420ba87e9db
https://doi.org/10.1101/2022.05.24.492634
https://doi.org/10.1101/2022.05.24.492634
Autor:
Stijn De Munter, Tessa Kerre, Lore Billiet, Hanne Jansen, Georges Leclercq, Joline Ingels, Sarah Bonte, Karin Weening, Glenn Goetgeluk, Tom Taghon, Bart Vandekerckhove, Laurenz De Cock, Melissa Pille
Publikováno v:
Oncoimmunology
article-version (VoR) Version of Record
OncoImmunology, Vol 10, Iss 1 (2021)
ONCOIMMUNOLOGY
article-version (VoR) Version of Record
OncoImmunology, Vol 10, Iss 1 (2021)
ONCOIMMUNOLOGY
T cell receptor (TCR)-redirected T cells target intracellular antigens such as Wilms’ tumor 1 (WT1), a tumor-associated antigen overexpressed in several malignancies, including acute myeloid leukemia (AML). For both chimeric antigen receptor (CAR)-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b58a17d2cada7740ea26397f1989d7bd
http://europepmc.org/articles/PMC8312599
http://europepmc.org/articles/PMC8312599
Autor:
Karim Vermaelen, Marieke Brusseel, Stijn De Munter, Melissa Pille, Joline Ingels, Saskia De Smet, Karin Weening, Glenn Goetgeluk, Rupert L. Mayer, Sarah Bonte, Kelly Heyns, Björn Menten, Tom Taghon, Nele Lootens, Sandra Van Lint, Bart Vandekerckhove, Pam Devreker, Francis Impens, Hanne Jansen, Laurenz De Cock, Georges Leclercq, Lore Billiet
Publikováno v:
CYTOTHERAPY
Messenger RNA (mRNA) has become a promising tool in therapeutic cancer vaccine strategies. Owing to its flexible design and rapid production, mRNA is an attractive antigen delivery format for cancer vaccines targeting mutated peptides expressed in a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7032069b26f4d7ac65c24f48ee61c71a
https://pubmed.ncbi.nlm.nih.gov/34696961
https://pubmed.ncbi.nlm.nih.gov/34696961
Autor:
Lore, Billiet, Glenn, Goetgeluk, Sarah, Bonte, Stijn, De Munter, Laurenz, De Cock, Melissa, Pille, Joline, Ingels, Hanne, Jansen, Karin, Weening, Filip, Van Nieuwerburgh, Tessa, Kerre, Tom, Taghon, Georges, Leclercq, Bart, Vandekerckhove
Publikováno v:
International Journal of Molecular Sciences
Human thymic CD8αα+ CD10+ PD-1+ αβ T cells selected through early agonist selection have been proposed as the putative thymic precursors of the human CD8αα+ intestinal intraepithelial lymphocytes (IELs). However, the progeny of these thymic pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::59209028f75a052c5a7d44c9e1491bf4
https://pubmed.ncbi.nlm.nih.gov/33233766
https://pubmed.ncbi.nlm.nih.gov/33233766
Autor:
Melissa Pille, Laurenz De Cock, Glenn Goetgeluk, Bart Vandekerckhove, Tessa Kerre, Lore Billiet, Joline Ingels, Tom Taghon, Stijn De Munter, Filip Van Nieuwerburgh, Hanne Jansen, Georges Leclercq, Karin Weening, Sarah Bonte
Publikováno v:
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
International Journal of Molecular Sciences, Vol 21, Iss 8785, p 8785 (2020)
International Journal of Molecular Sciences, Vol 21, Iss 8785, p 8785 (2020)
Human thymic CD8αα+ CD10+ PD-1+ αβ T cells selected through early agonist selection have been proposed as the putative thymic precursors of the human CD8αα+ intestinal intraepithelial lymphocytes (IELs). However, the progeny of these thymic pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8898767d5e06c36d349cfd2188fe6f51
https://biblio.ugent.be/publication/8681673
https://biblio.ugent.be/publication/8681673