Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Laurenz, Steiner"'
Autor:
Eva Altrock, Carla Sens-Albert, Franziska Hofmann, Vladimir Riabov, Nanni Schmitt, Qingyu Xu, Johann-Christoph Jann, Felicitas Rapp, Laurenz Steiner, Alexander Streuer, Verena Nowak, Julia Obländer, Nadine Weimer, Iris Palme, Melda Göl, Ali Darwich, Patrick Wuchter, Georgia Metzgeroth, Mohamad Jawhar, Wolf-Karsten Hofmann, Daniel Nowak
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Background Robust and reliable in vitro and in vivo models of primary cells are necessary to study the pathomechanisms of Myelodysplastic Neoplasms (MDS) and identify novel therapeutic strategies. MDS-derived hematopoietic stem and progenito
Externí odkaz:
https://doaj.org/article/3d993a6d3dfe43489fb55296d3d2a803
Autor:
Qingyu Xu, Alexander Streuer, Johann-Christoph Jann, Eva Altrock, Nanni Schmitt, Johanna Flach, Carla Sens-Albert, Felicitas Rapp, Julia Wolf, Verena Nowak, Nadine Weimer, Julia Obländer, Iris Palme, Mariia Kuzina, Ahmed Jawhar, Ali Darwich, Cleo-Aron Weis, Alexander Marx, Patrick Wuchter, Victor Costina, Evelyn Jäger, Elena Sperk, Michael Neumaier, Alice Fabarius, Georgia Metzgeroth, Florian Nolte, Laurenz Steiner, Pavel A. Levkin, Mohamad Jawhar, Wolf-Karsten Hofmann, Vladimir Riabov, Daniel Nowak
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Hypomethylating agents, such as 5-Azacytidine (5-AZA), are standard of care for patients with myelodysplastic and myeloid malignancies, however response rates are limited and risk of relapses high. Here the authors show that inhibition of lysyl oxida
Externí odkaz:
https://doaj.org/article/91b523f59ac547d99572fb13b46e1d2f
Autor:
Vladimir Riabov, Qingyu Xu, Nanni Schmitt, Alexander Streuer, Guo Ge, Lyndsey Bolanos, Mark Wunderlich, Johann-Christoph Jann, Alina Wein, Eva Altrock, Marie Demmerle, Sanjay Mukherjee, Abdullah Mahmood Ali, Felicitas Rapp, Verena Nowak, Nadine Weimer, Julia Obländer, Iris Palme, Melda Göl, Ahmed Jawhar, Ali Darwich, Patrick Wuchter, Christel Weiss, Azra Raza, Jason M. Foulks, Daniel T. Starczynowski, Feng-Chun Yang, Georgia Metzgeroth, Laurenz Steiner, Mohamad Jawhar, Wolf-Karsten Hofmann, Daniel Nowak
Publikováno v:
Haematologica, Vol 109, Iss 5 (2023)
Inhibitors of anti-apoptotic BCL-2 family proteins in combination with chemotherapy and hypomethylating agents (HMA) are promising therapeutic approaches in acute myeloid leukemia (AML) and high-risk myelodysplastic syndromes (MDS). Alvocidib, a cycl
Externí odkaz:
https://doaj.org/article/587fe7bf73e84c44b2b804ab4433a656
Autor:
Petra Beschoner, Jörn von Wietersheim, Marc N. Jarczok, Maxi Braun, Carlos Schönfeldt-Lecuona, Lucia Jerg-Bretzke, Laurenz Steiner
Publikováno v:
Frontiers in Psychiatry, Vol 11 (2020)
Background: International studies have shown that among physicians working in intensive care, a relatively high level of work load, an elevated risk of developing burnout and reduced mental health are frequent. The implementation of a legislative int
Externí odkaz:
https://doaj.org/article/faab2f392c5f466f91deb072cde3a922
Autor:
Eva Altrock, Carla Sens-Albert, Johann-Christoph Jann, Johanna Flach, Vladimir Riabov, Nanni Schmitt, Qingyu Xu, Arwin Mehralivand, Anna Hecht, Laurenz Steiner, Alexander Streuer, Verena Nowak, Julia Obländer, Nadine Weimer, Iris Palme, Ahmed Jawhar, Cleo-Aron Weis, Vanessa Weyer, Florian Nolte, Mohamad Jawhar, Georgia Metzgeroth, Alexander Marx, Christoph Groden, Wolf-Karsten Hofmann, Daniel Nowak
Publikováno v:
Experimental Hematology. 107:38-50
Patient-derived xenograft (PDX) models have emerged as versatile preclinical platforms for investigation of functional pathomechanisms in myelodysplastic syndromes (MDS) and other myeloid neoplasms. However, despite increasingly improved methodology,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55044dc3cdd1c8fe21088ada30b6a819
https://doi.org/10.1016/j.exphem.2021.12.395
https://doi.org/10.1016/j.exphem.2021.12.395
Autor:
Petra Beschoner, Lucia Jerg-Bretzke, Maxi Braun, Carlos Schönfeldt-Lecuona, Edit Rottler, Aniela Brück, Laurenz Steiner, Maximilian Johannes Kempf, Jörn von Wietersheim
Publikováno v:
Das Gesundheitswesen. 84:1094-1100
Zusammenfassung Ziel der Studie Mobbing am Arbeitsplatz gilt als interpersoneller Stressfaktor. Beruflicher Stress und mentale Gesundheit bei Ärztinnen und Ärzten rücken zunehmend in den Fokus der Öffentlichkeit. Inwiefern Mobbing dabei eine Roll
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3832a6daab67b0afc68c5909e4be222
https://doi.org/10.1055/a-1581-7896
https://doi.org/10.1055/a-1581-7896
Autor:
Wolf-Karsten Hofmann, Arwin Mehralivand, Laurenz Steiner, Nanni Schmitt, Ahmed Jawhar, Cleo-Aron Weis, Stefanie Uhlig, Justine Danner, Vladimir Riabov, Ali Darwich, Qingyu Xu, Julia Obländer, Eva Altrock, Tobias Boch, Nadine Weimer, Florian Nolte, Antje Knaflic, Mohamad Jawhar, Alexander Streuer, Verena Haselmann, Daniel Nowak, Johann-Christoph Jann, Verena Nowak, Alexander Marx, Georgia Metzgeroth, Johanna Flach, Iris Palme
Publikováno v:
Leukemia
Preclinical research of myelodysplastic syndromes (MDSs) is hampered by a lack of feasible disease models. Previously, we have established a robust patient-derived xenograft (PDX) model for MDS. Here we demonstrate for the first time that this model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9748a1e6c1fc1292c3557204eb8226a6
http://europepmc.org/articles/PMC8727300
http://europepmc.org/articles/PMC8727300
Autor:
Qingyu Xu, Alexander Streuer, Johann-Christoph Jann, Eva Altrock, Nanni Schmitt, Johanna Flach, Carla Sens-Albert, Felicitas Rapp, Julia Wolf, Verena Nowak, Nadine Weimer, Julia Obländer, Iris Palme, Ahmed Jawhar, Ali Darwich, Cleo-Aron Weis, Alexander Marx, Patrick Wuchter, Victor Costina, Evelyn Jäger, Elena Sperk, Michael Neumaier, Alice Fabarius, Georgia Metzgeroth, Florian Nolte, Laurenz Steiner, Mohamad Jawhar, Wolf-Karsten Hofmann, Vladimir Riabov, Daniel Nowak
Publikováno v:
Blood. 140:3054-3055
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9555b59661f4f67239bc2b452726b54
https://doi.org/10.1182/blood-2022-159507
https://doi.org/10.1182/blood-2022-159507
Autor:
Vladimir Riabov, Qingyu Xu, Nanni Schmitt, Alexander Streuer, Guo Ge, Johann-Christoph Jann, Alina Wein, Eva Altrock, Felicitas Rapp, Verena Nowak, Nadine Weimer, Julia Obländer, Iris Palme, Melda Göl, Mark Wunderlich, Ahmed Jawhar, Ali Darwich, Patrick Wuchter, Christel Weiss, Jason M Foulks, Daniel T. Starczynowski, Feng-Chun Yang, Georgia Metzgeroth, Laurenz Steiner, Wolf-Karsten Hofmann, Daniel Nowak, Mohamad Jawhar
Publikováno v:
Blood. 140:9749-9750
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f17853153caf5c748fcc44c88a303b13
https://doi.org/10.1182/blood-2022-165298
https://doi.org/10.1182/blood-2022-165298
Autor:
Laurenz Steiner, Navkirandeep Kaur, Alexander Streuer, Johann-Christoph Jann, Alice Fabarius, Georgia Metzgeroth, Wolf-Karsten Hofmann, Daniel Nowak, Mohamad Jawhar
Publikováno v:
Blood. 140:9831-9832
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66ac0eb4bc60042ae44595d5ec46365a
https://doi.org/10.1182/blood-2022-168850
https://doi.org/10.1182/blood-2022-168850