Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Laurent R. Gauthier"'
Autor:
Amandine Bery, Olivier Etienne, Laura Mouton, Sofiane Mokrani, Christine Granotier-Beckers, Laurent R. Gauthier, Justyne Feat-Vetel, Thierry Kortulewski, Elodie A. Pérès, Chantal Desmaze, Philippe Lestaveal, Vilma Barroca, Antony Laugeray, Fawzi Boumezbeur, Vincent Abramovski, Stéphane Mortaud, Arnaud Menuet, Denis Le Bihan, Jean-Pierre de Villartay, François D. Boussin
Publikováno v:
Cell Reports, Vol 42, Iss 4, Pp 112342- (2023)
Summary: XLF/Cernunnos is a component of the ligation complex used in classical non-homologous end-joining (cNHEJ), a major DNA double-strand break (DSB) repair pathway. We report neurodevelopmental delays and significant behavioral alterations assoc
Externí odkaz:
https://doaj.org/article/932eb1262b3c484399e5f2d802035f1e
Autor:
Lise Morizur, Alexandra Chicheportiche, Laurent R. Gauthier, Mathieu Daynac, François D. Boussin, Marc-André Mouthon
Publikováno v:
Stem Cell Reports, Vol 11, Iss 2, Pp 565-577 (2018)
Summary: Deciphering the mechanisms that regulate the quiescence of adult neural stem cells (NSCs) is crucial for the development of therapeutic strategies based on the stimulation of their endogenous regenerative potential in the damaged brain. We s
Externí odkaz:
https://doaj.org/article/f6de8799444748aa8c0413d23111a340
Autor:
Mathieu Daynac, Linda Tirou, Hélène Faure, Marc-André Mouthon, Laurent R. Gauthier, Heidi Hahn, François D. Boussin, Martial Ruat
Publikováno v:
Stem Cell Reports, Vol 7, Iss 4, Pp 735-748 (2016)
Identifying the mechanisms controlling quiescence and activation of neural stem cells (NSCs) is crucial for understanding brain repair. Here, we demonstrate that Hedgehog (Hh) signaling actively regulates different pools of quiescent and proliferativ
Externí odkaz:
https://doaj.org/article/27a6e426bd4940a6a9431b0a9d15ec0e
Autor:
Didier Busso, Ada Collura, Mahasen Saati, Marie-Pierre Junier, Karim Ben M'Barek, Romane Bertrand, Marc-André Mouthon, Hayet Bensalah-Pigeon, Oscar Gitton-Quent, François D. Boussin, José R Pineda, Laurent R. Gauthier, Hervé Chneiweiss
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports
Scientific Reports, 2020, 10 (1), pp.18742. ⟨10.1038/s41598-020-75300-5⟩
Scientific Reports, Nature Publishing Group, 2020, 10 (1), pp.18742. ⟨10.1038/s41598-020-75300-5⟩
Scientific Reports
Scientific Reports, 2020, 10 (1), pp.18742. ⟨10.1038/s41598-020-75300-5⟩
Scientific Reports, Nature Publishing Group, 2020, 10 (1), pp.18742. ⟨10.1038/s41598-020-75300-5⟩
Human glioblastoma (GBM) is the most common primary malignant brain tumor. A minor subpopulation of cancer cells, known as glioma stem-like cells (GSCs), are thought to play a major role in tumor relapse due to their stem cell-like properties, their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19428df5b34969e9e606b879f3f86d18
http://link.springer.com/article/10.1038/s41598-020-75300-5
http://link.springer.com/article/10.1038/s41598-020-75300-5
Publikováno v:
International Journal of Cancer. 136:982-988
The hematopoietic growth factor granulocyte colony-stimulating factor (G-CSF) has a role in proliferation, differentiation and migration of the myeloid lineage and in mobilizing hematopoietic stem and progenitor cells into the bloodstream. However, G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4670dc806516c15b143ff795bf05ba0
https://doi.org/10.1002/ijc.29046
https://doi.org/10.1002/ijc.29046
Publikováno v:
International journal of cancer. 136(4)
The hematopoietic growth factor granulocyte colony-stimulating factor (G-CSF) has a role in proliferation, differentiation and migration of the myeloid lineage and in mobilizing hematopoietic stem and progenitor cells into the bloodstream. However, G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4d71d4d540df5cee2108a574ea176200
https://pubmed.ncbi.nlm.nih.gov/24975135
https://pubmed.ncbi.nlm.nih.gov/24975135
Autor:
Eliane Mandine, Denis Biard, Laurent R. Gauthier, Gaëlle Pennarun, Christine Granotier, Françoise Hoffschir, François D. Boussin
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, Oxford University Press, 2008, 36 (5), pp.1741-54. ⟨10.1093/nar/gkn026⟩
Nucleic Acids Research, 2008, 36 (5), pp.1741-54. ⟨10.1093/nar/gkn026⟩
Nucleic Acids Research, Oxford University Press, 2008, 36 (5), pp.1741-54. ⟨10.1093/nar/gkn026⟩
Nucleic Acids Research, 2008, 36 (5), pp.1741-54. ⟨10.1093/nar/gkn026⟩
Telomeres are known to prevent chromosome ends from being recognized as DNA double-strand breaks. Conversely, many DNA damage response proteins, including ATM, are thought to participate to telomere maintenance. However, the precise roles of ATM at t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::162097c4422e02d76b8466661cd371bf
https://hal-cea.archives-ouvertes.fr/cea-00268952
https://hal-cea.archives-ouvertes.fr/cea-00268952
Autor:
Céline Mathieu, Pierre Fouchet, Bruno Lassalle, Marc-André Mouthon, François D. Boussin, Laurent R. Gauthier
Publikováno v:
Experimental cell research. 312(6)
Neural stem cell proliferation and differentiation are regulated by external cues from their microenvironment. As endothelial cells are closely associated with neural stem cell in brain germinal zones, we investigated whether endothelial cells may in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35cc305a533f7bd0e94b482fd44d5f7e
https://pubmed.ncbi.nlm.nih.gov/16343482
https://pubmed.ncbi.nlm.nih.gov/16343482
Autor:
François D. Boussin, Christine Granotier, Olivier Etienne, Laurent R. Gauthier, Celine S. Lages, Julien Comte, Gaëlle Pennarun
Publikováno v:
Journal of cellular biochemistry. 93(5)
TRF1 and Pin2 play an essential role in telomere homeostasis, by regulating telomere maintenance. They are generated from the same gene, TRF1/Pin2, by alternative splicing but no functional differences between these proteins have been demonstrated. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a338f0cd7d44467e44154e62f8a4569
https://pubmed.ncbi.nlm.nih.gov/15389875
https://pubmed.ncbi.nlm.nih.gov/15389875
Autor:
Stéphane Haïk, François D. Boussin, Celine S. Lages, Dominique Dormont, Christine Granotier, Laurent R. Gauthier, Jean-Michel Peyrin
Publikováno v:
Oncogene. 19(26)
During brain development, neuronal and glial cells are generated from neural precursors on a precise schedule involving steps of proliferation, fate commitment and differentiation. We report that telomerase activity is highly expressed during embryon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa67aa450bf9c7634b4e5bb61be9debf
https://pubmed.ncbi.nlm.nih.gov/10871847
https://pubmed.ncbi.nlm.nih.gov/10871847