Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Laurent Perreard"'
Autor:
Min Kyung Lee, Nasim Azizgolshani, Ze Zhang, Laurent Perreard, Fred W. Kolling, Lananh N. Nguyen, George J. Zanazzi, Lucas A. Salas, Brock C. Christensen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Although intratumoral heterogeneity has been established in pediatric central nervous system tumors, epigenomic alterations at the cell type level have largely remained unresolved. To identify cell type-specific alterations to cytosine modif
Externí odkaz:
https://doaj.org/article/0f056dd83a1c4f31861e1c0484d38c51
Autor:
Michael Fatemi, Eric Feng, Cyril Sharma, Zarif Azher, Tarushii Goel, Ojas Ramwala, Scott M. Palisoul, Rachael E. Barney, Laurent Perreard, Fred W. Kolling, Lucas A. Salas, Brock C. Christensen, Gregory J. Tsongalis, Louis J. Vaickus, Joshua J. Levy
Publikováno v:
Journal of Pathology Informatics, Vol 14, Iss , Pp 100308- (2023)
Over 150 000 Americans are diagnosed with colorectal cancer (CRC) every year, and annually over 50 000 individuals will die from CRC, necessitating improvements in screening, prognostication, disease management, and therapeutic options. Tumor metasta
Externí odkaz:
https://doaj.org/article/1181f9f5d62e4f3aa971a195e9b8ba88
Publikováno v:
Epigenomics
Aim: Tandem bisulfite (BS) and oxidative bisulfite (oxBS) conversion on DNA followed by hybridization to Infinium HumanMethylation BeadChips allows nucleotide resolution of 5-hydroxymethylcytosine genome-wide. Here, the authors compared data quality
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c57977450eaccd5e3a0ebca5afd9c148
https://doi.org/10.2217/epi-2021-0490
https://doi.org/10.2217/epi-2021-0490
Autor:
Min Kyung Lee, Nasim Azizgolshani, Ze Zhang, Laurent Perreard, Fred Kolling IV, Lananh Nguyen, George Zanazzi, Lucas Salas, Brock Christensen
Although intratumoral heterogeneity has been established in pediatric central nervous system tumors, epigenomic alterations at the cell type level have largely remained unresolved. To identify cell type-specific alterations to cytosine modifications
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::330df0e5f6e491c04ac60d7ec42ae46d
https://doi.org/10.21203/rs.3.rs-2517758/v1
https://doi.org/10.21203/rs.3.rs-2517758/v1
Autor:
Michael Fatemi, Eric Feng, Cyril Sharma, Zarif Azher, Tarushii Goel, Ojas Ramwala, Scott Palisoul, Rachael Barney, Laurent Perreard, Fred Kolling, Lucas A. Salas, Brock C. Christensen, Gregory Tsongalis, Louis Vaickus, Joshua J. Levy
Over 150,000 Americans are diagnosed with colorectal cancer (CRC) every year, and annually over 50,000 individuals will die from CRC, necessitating improvements in screening, prognostication, disease management, and therapeutic options. Tumor metasta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9dd6fe5ad782f96882f59d00a7cbdc43
https://doi.org/10.1101/2022.11.24.517856
https://doi.org/10.1101/2022.11.24.517856
Autor:
Brock C. Christensen, Youdinghuan Chen, Laurent Perreard, Lucas A. Salas, Lananh N Nguyen, Joshua J. Levy, Curtis L. Petersen, Nasim Azizgolshani
Publikováno v:
Clinical Epigenetics
Background Nucleotide-specific 5-hydroxymethylcytosine (5hmC) remains understudied in pediatric central nervous system (CNS) tumors. 5hmC is abundant in the brain, and alterations to 5hmC in adult CNS tumors have been reported. However, traditional a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9fa7d95463982e6ce6de97024652cf1
https://doi.org/10.1186/s13148-021-01156-9
https://doi.org/10.1186/s13148-021-01156-9
Autor:
Youdinghuan Chen, Nasim Azizgolshani, Laurent Perreard, Brock C. Christensen, Lucas A. Salas, Curtis L. Petersen, Lananh N Nguyen
Nucleotide-specific 5-hydroxymethylcytosine (5hmC) remains understudied in pediatric central nervous system tumors. We measured genome-scale 5hmC in glioma, ependymoma, and embryonal tumors from children, as well as control pediatric brain tissues us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fffae51fd911e5acb93466a57e2637cd
https://doi.org/10.1101/2020.06.20.20136184
https://doi.org/10.1101/2020.06.20.20136184
Autor:
Curtis L. Petersen, Lucas A. Salas, Brock C. Christensen, Laurent Perreard, Nasim Azizgolshani, Lananh N Nguyen, Youdinghuan Chen
Publikováno v:
Neuro-Oncology
Though aberrant cytosine modifications are prevalent in cancer, nucleotide-specific 5-hydroxymethylcytosine (5hmC) modifications remain understudied, including in pediatric CNS tumors. Brain 5-hydroxymethylation is linked with development and differe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba0302dd4e0703e0513eb5093decfa3b
http://europepmc.org/articles/PMC7715137
http://europepmc.org/articles/PMC7715137
Autor:
Margaret R. Karagas, John D. Seigne, Karl T. Kelsey, Laurent Perreard, Alan R. Schned, Angeline S. Andrew, Carmen J. Marsit, Lorenzo F. Sempere, Jason H. Moore
Publikováno v:
International Journal of Cancer. 137:1158-1166
Bladder cancer is the fourth most common cancer among men in the United States and more than half of patients experience recurrences within 5 years after initial diagnosis. Additional clinically informative and actionable biomarkers of the recurrent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a836180745198f05fbe8720329aabc20
https://doi.org/10.1002/ijc.29413
https://doi.org/10.1002/ijc.29413
Autor:
Aniko Szabo, Laurent Perreard, Michael Mullins, Matthew J. Ellis, Philip S. Bernard, Charles M. Perou, Steven Bayer, Nicholas P. Gauthier, John Quackenbush, Joel S. Parker
Publikováno v:
Clinical Chemistry. 53:1273-1279
Background: Microarray studies have identified different molecular subtypes of breast cancer with prognostic significance. To transition these classifications into the clinical laboratory, we have developed a real-time quantitative reverse transcript
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bf10e43492281ec2f1439dcb7867436
https://doi.org/10.1373/clinchem.2006.083725
https://doi.org/10.1373/clinchem.2006.083725