Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Laurent Nault"'
Autor:
Karim Chouchane, Thibaut Frachon, Laurent Marichal, Laurent Nault, Charlotte Vendrely, Antoine Maze, Franz Bruckert, Marianne Weidenhaupt
Publikováno v:
Colloids and Surfaces B: Biointerfaces. 214:112451
The consequences of agitation on protein stability are particularly relevant to therapeutic proteins. However, the precise contribution of the different effects induced by agitation in pathways leading to protein denaturation and aggregation at inter
Autor:
Bhagyashree Jain, Marianne Weidenhaupt, Franz Bruckert, Perry Guo, Yves Bréchet, Laurent Nault
Publikováno v:
Acta Biomaterialia
Acta Biomaterialia, Elsevier, 2013, 9 (2), pp.5070-5079. ⟨10.1016/j.actbio.2012.09.025⟩
Acta Biomaterialia, Elsevier, 2013, 9 (2), pp.5070-5079. ⟨10.1016/j.actbio.2012.09.025⟩
International audience; The formation of insulin amyloidal aggregates on material surfaces is a well-known phenomenon with important pharmaceutical and medical implications. Using surface plasmon resonance imaging, we monitor insulin adsorption on mo
Publikováno v:
Antioxidantsredox signaling. 25(10)
Reactive oxygen species (ROS) fulfill numerous roles in biology ranging from signal transduction to the induction of cell death. To advance our understanding of these sometimes contradictory roles, quantitative, specific, and sensitive ROS measuremen
Autor:
Thierry Michon, Agnès Anne, Daniela Cardinale, Noëlle Carette, Laurent Nault, Arnaud Chovin, Cécilia Taofifenua, Jocelyne Walter, Jane Besong-Ndika, Christophe Demaille
Publikováno v:
ACS Nano
ACS Nano, American Chemical Society, 2015, 9 (5), pp.4911-4924. ⟨10.1021/acsnano.5b00952⟩
ACS Nano, American Chemical Society, 2015, 9 (5), pp.4911-4924. ⟨10.1021/acsnano.5b00952⟩
International audience; We show herein that electrochemical atomic force microscopy (AFM-SECM), operated in molecule touching (Mt) mode and combined with redox immunomarking, enables the in situ mapping of the distribution of proteins on individual v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c7027fb3fcc636eb21b606725db6ca4
https://hal.inrae.fr/hal-02641377
https://hal.inrae.fr/hal-02641377
Autor:
Laurence Boulangé, Laurent Nault, Thomas Perret, Marianne Weidenhaupt, Franz Brukert, Paolo Mangiagalli, Christophe Bureau, Thomas Ballet
Publikováno v:
Biochemistry
Biochemistry, American Chemical Society, 2012, 51 (11), pp.2172-2180. ⟨10.1021/bi201457u⟩
Biochemistry, American Chemical Society, 2012, 51 (11), pp.2172-2180. ⟨10.1021/bi201457u⟩
International audience; We have developed a multiwell-based protein aggregation assay to study the kinetics of insulin adsorption and aggregation on hydrophobic surfaces and to investigate the molecular mechanisms involved. Protein-surface interactio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e66b964a948eaf6bf25b0bc7938879f6
https://hal.archives-ouvertes.fr/hal-01067505
https://hal.archives-ouvertes.fr/hal-01067505
Publikováno v:
Chemical Communications. 46:5581
Polycationic calixarene-based solid lipid nanoparticles (SLNs) have been loaded at their surface with DNA and chitosan and studied for their ability to transfect mammalian cells.
Autor:
Thomas Perrotton, Laurent Nault, Antoine Leydier, Celine Girardot, Anthony W. Coleman, Sandrine Magnard, Hélène Baubichon-Cortay
Publikováno v:
New Journal of Chemistry. 34:1812
The tri-carboxylatomethylene-mono-alkoxy calix[4]arenes have been shown by fluorescence spectroscopy to bind to the NBD1 domain of MRP1 protein in a magnesium dependent manner. The observed associations constants are of the same order as that observe