Výsledky vyhledávání - "Laurent Léotoing"

Akademický článek

The polyphenol fisetin protects bone by repressing NF-κB and MKP-1-dependent signaling pathways in osteoclasts.

Autor: Laurent Léotoing, Fabien Wauquier, Jérôme Guicheux, Elisabeth Miot-Noirault, Yohann Wittrant, Véronique Coxam

Publikováno v: PLoS ONE, Vol 8, Iss 7, p e68388 (2013)

Osteoporosis is a bone pathology leading to increase fractures risk and challenging quality of life. Since current treatments could exhibit deleterious side effects, the use of food compounds derived from plants represents a promising innovative alte

Externí odkaz: https://doaj.org/article/ce572c28d9b3426bb81a1c1f2187f341

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Commentary on : Prebiotic effects: metabolic and health benefits

In 2010, British Journal of Nutrition published a consensus review article entitled Prebiotic effects: metabolic and health benefits(1). This was commissioned by International Life Sciences Institute, Europe and had twenty-one co-authors. The current

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::413162926eb04bc0213f8e10abc6523e
http://hdl.handle.net/10044/1/93289

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The flavonoid fisetin promotes osteoblasts differentiation through Runx2 transcriptional activity

Autor: Patrice Lebecque, Véronique Coxam, Yohann Wittrant, Marie-Jeanne Davicco, Laurent Léotoing

Publikováno v: Molecular Nutrition and Food Research
Molecular Nutrition and Food Research, Wiley-VCH Verlag, 2014, 58 (6), pp.1239-1248. ⟨10.1002/mnfr.201300836⟩
Molecular Nutrition and Food Research, 2014, 58 (6), pp.1239-1248. ⟨10.1002/mnfr.201300836⟩

cope Flavonoids represent a group of polyphenolic compounds commonly found in daily nutrition with proven health benefits. Among this group, the flavonol fisetin has been previously shown to protect bone by repressing osteoclast differentiation. In t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6756d27f690bf77bd015cb69a7a1e84
https://doi.org/10.1002/mnfr.201300836

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The phenolic acids of Agen prunes (dried plums) or Agen prune juice concentrates do not account for the protective action on bone in a rat model of postmenopausal osteoporosis

Autor: Stephane Rey, Salim Rashidi, Fabien Wauquier, Patrice Lebecque, Véronique Coxam, David Gaudout, Yohann Wittrant, Laurent Massenat, Marie-Jeanne Davicco, Laurent Léotoing, Xavier Vitrac

Publikováno v: Nutrition Research
Nutrition Research, Elsevier, 2016, 36 (2), pp.161-173. ⟨10.1016/j.nutres.2015.10.002⟩
Nutrition Research, 2016, 36 (2), pp.161-173. ⟨10.1016/j.nutres.2015.10.002⟩

Dietary supplementation with dried plum (DP) has been shown to protect against and reverse established osteopenia in ovariectomized rodents. Based on in vitro studies, we hypothesized that DP polyphenols may be responsible for that bone-sparing effec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68e850a957a29f259c8e9b698b14c300
https://hal.archives-ouvertes.fr/hal-01299595

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Oxidative stress in bone remodelling and disease

Autor: Fabien Wauquier, Yohann Wittrant, Véronique Coxam, Jérôme Guicheux, Laurent Léotoing

Publikováno v: Trends in Molecular Medicine. 15:468-477

Oxidative stress is characterised by an increased level of reactive oxygen species (ROS) that disrupts the intracellular reduction-oxidation (redox) balance. Although initially shown to be involved in aging, physiological roles for ROS in regulating

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19d7faeebb1c7acfdeb010aeb840ca93
https://doi.org/10.1016/j.molmed.2009.08.004

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The polyphenol fisetin protects bone by repressing NF-kB and MKP-1-dependent signaling pathways in osteoclasts

Autor: Elisabeth Miot-Noirault, Yohann Wittrant, Fabien Wauquier, Laurent Léotoing, Jérôme Guicheux, Véronique Coxam

Publikováno v: 17. Journées Françaises de Biologie des Tissus Minéralisés, JFBTM
17. Journées Françaises de Biologie des Tissus Minéralisés JFBTM, Société Française de Biologie des Tissus Minéralisés (SFBTM). FRA., Feb 2015, Clermont-Ferrand, France
Plos One 7 (8), . (2013)
XVIIèmes Journées Françaises de Biologie des Tissus Minéralisés. 2015; 17. Journées Françaises de Biologie des Tissus Minéralisés, JFBTM, Clermont-Ferrand, FRA, 2015-02-04-2015-02-06, n.p.
PLoS ONE, Vol 8, Iss 7, p e68388 (2013)
PLoS ONE
PLoS ONE, Public Library of Science, 2013, 8 (7), pp.68388-68388. ⟨10.1371/journal.pone.0068388⟩
PLoS ONE, 2013, 8 (7), pp.68388-68388. ⟨10.1371/journal.pone.0068388⟩

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1779587bd8cb805e983296adbc629ff4
https://hal.inrae.fr/hal-02740430

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Pomegranate Peel Extract Prevents Bone Loss in a Preclinical Model of Osteoporosis and Stimulates Osteoblastic Differentiation in Vitro

Autor: Laurent Léotoing, P. Pilet, Elisabeth Miot-Noirault, Laurent Rios, Véronique Coxam, Mélanie Spilmont, Marie-Jeanne Davicco, Patrice Lebecque, Yohann Wittrant

Publikováno v: Nutrients
Nutrients, MDPI, 2015, 7 (11), pp.9265-9284. ⟨10.3390/nu7115465⟩
Nutrients, Vol 7, Iss 11, Pp 9265-9284 (2015)
Nutrients; Volume 7; Issue 11; Pages: 9265-9284
Nutrients 11 (7), 9265-9284. (2015)
Nutrients, 2015, 7 (11), pp.9265-9284. ⟨10.3390/nu7115465⟩

The nutritional benefits of pomegranate have attracted great scientific interest. The pomegranate, including the pomegranate peel, has been used worldwide for many years as a fruit with medicinal activity, mostly antioxidant properties. Among chronic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59077499f5fc6d1b06e12801fd0ca5bb
https://hal.archives-ouvertes.fr/hal-01248815/document

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Pros and cons of fatty acids in bone biology

Autor: Laurent Léotoing, Fabien Wauquier, Yohann Wittrant, Claire Philippe, Mélanie Spilmont, Véronique Coxam

Publikováno v: Progress in Lipid Research
Progress in Lipid Research, Elsevier, 2015, 58, pp.121-145. ⟨10.1016/j.plipres.2015.03.001⟩
Progress in Lipid Research, 2015, 58, pp.121-145. ⟨10.1016/j.plipres.2015.03.001⟩

Despite the growing interest in deciphering the causes and consequences of obesity-related disorders, the mechanisms linking fat intake to bone behaviour remain unclear. Since bone fractures are widely associated with increased morbidity and mortalit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7fe5646708c36f415a21f33d2430855
https://hal.archives-ouvertes.fr/hal-01206984

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Des régimes enrichis en pruneau d’Agen ou en concentré de jus de pruneau d’Agen permettent de prévenir la perte osseuse dans un modèle d’ostéoporose post-ménopausique indépendamment de leur richesse en acides phénoliques

Autor: L. Massenat, Yohann Wittrant, Véronique Coxam, S. Rashidi, Fabien Wauquier, X. Vitrac, Patrice Lebecque, S. Rey, Marie-Jeanne Davicco, D. Gaudout, Laurent Léotoing

Publikováno v: Nutrition Clinique et Métabolisme. 30:256-257

Introduction et but de l’etude La supplementation d’un regime avec du pruneau permet de prevenir et d’inverser une perte osseuse induite par privation estrogenique chez la ratte. Sur la base d’etudes in vitro, nous avons emis l’hypothese qu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b2afb4c919c10ae65e72c7c3bbfd969b
https://doi.org/10.1016/j.nupar.2016.09.078

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Bone health maintenance: Innovative nutritional strategy by polyphenols

Autor: Yohann Wittrant, Véronique Coxam, Marie-Jeanne Davicco, Laurent Léotoing

Publikováno v: Planta Medica
62èmes International Congress and Annual Meeting of the Society-of-Medicinal-Plant-and-Natural-Product-Research
62. International Congress and Annual Meeting of the Society-of-Medicinal-Plant-and-Natural-Product-Research
62. International Congress and Annual Meeting of the Society-of-Medicinal-Plant-and-Natural-Product-Research, Society for Medical Plant and Natural Product Research (GA) (GA). Neunkirchen am Brand, DEU., Aug 2014, Guimaraes, Portugal. n.p, ⟨10.1055/s-0034-1394565⟩
62. International Congress and Annual Meeting of the Society-of-Medicinal-Plant-and-Natural-Product-Research, Aug 2014, Guimaraes, Portugal. n.p, ⟨10.1055/s-0034-1394565⟩

Sponsor(s):Soc Med Plant & Nat Prod ResSponsor(s):Soc Med Plant & Nat Prod Res; With the continuing demographic shift in population toward an older society, all industrialised countries face a growing prevalence of chronic age-related conditions. Amo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::583244b38b7ece09094d50154f14cc76
https://hal.science/hal-01123104

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