A New Method for Rapid Screening of End-Point PCR Products: Application to Single Genome Amplified HIV and SIV Envelope Amplicons.

Autor: Laurent Houzet, Claire Deleage, Anne-Pascale Satie, Laetitia Merlande, Dominique Mahe, Nathalie Dejucq-Rainsford

Publikováno v: PLoS ONE, Vol 10, Iss 6, p e0128188 (2015)

PCR is the most widely applied technique for large scale screening of bacterial clones, mouse genotypes, virus genomes etc. A drawback of large PCR screening is that amplicon analysis is usually performed using gel electrophoresis, a step that is ver

Externí odkaz: https://doaj.org/article/a70c59a673354c4485d801a26628baf6

From Ancient to Emerging Infections: The Odyssey of Viruses in the Male Genital Tract

Autor: Giulia Matusali, Anna Le Tortorec, Séverine Mazaud-Guittot, Florence Aubry, Laurent Houzet, Nathalie Dejucq-Rainsford, Dominique Mahé

Publikováno v: Physiological Reviews
Physiological Reviews, American Physiological Society, 2020, 100 (3), pp.1349-1414. ⟨10.1152/physrev.00021.2019⟩
Physiological Reviews, 2020, 100 (3), pp.1349-1414. ⟨10.1152/physrev.00021.2019⟩

International audience; The male genital tract (MGT) is the target of a number of viral infections that can have deleterious consequences at the individual, offspring and population levels. These consequences include infertility, cancers of male orga

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a41cd6212f0208972082931fd689081f
https://doi.org/10.1152/physrev.00021.2019

Seminal Simian Immunodeficiency Virus in Chronically Infected Cynomolgus Macaques Is Dominated by Virus Originating from Multiple Genital Organs

Autor: Laurent, Houzet, Marcos, Pérez-Losada, Giulia, Matusali, Claire, Deleage, Nathalie, Dereuddre-Bosquet, Anne-Pascale, Satie, Florence, Aubry, Emmanuelle, Becker, Bernard, Jégou, Roger, Le Grand, Brandon F, Keele, Keith A, Crandall, Nathalie, Dejucq-Rainsford

Publikováno v: Journal of Virology

The sexual transmission of viruses is responsible for the spread of multiple infectious diseases. Although the human immunodeficiency virus (HIV)/AIDS pandemic remains fueled by sexual contacts with infected semen, the origin of virus in semen is sti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5509cfadf871e061cf7b8ea8f59eeb54
https://pubmed.ncbi.nlm.nih.gov/29720516

MicroRNAs and human retroviruses

Autor: Laurent Houzet, Kuan-Teh Jeang

Publikováno v: Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms

MicroRNAs (miRNAs) are small non-coding RNAs that control a multitude of critical processes in mammalian cells. Increasing evidence has emerged that host miRNAs serve in animal cells to restrict viral infections. In turn, many viruses encode RNA sile

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::809e25906c6918bcfe7241af31d24a25
https://doi.org/10.1016/j.bbagrm.2011.05.009

Nucleocapsid mutations turn HIV-1 into a DNA-containing virus

Autor: Delphine Muriaux, Zakia Morichaud, Marylène Mougel, Laurent Houzet, Jean-Luc Darlix, Ludovic Didierlaurent

Publikováno v: Nucleic Acids Research
Nucleic Acids Research, 2008, 36 (7), ⟨10.1093/nar/gkn069⟩
Nucleic Acids Research, Oxford University Press, 2008, 36 (7), ⟨10.1093/nar/gkn069⟩

Retroviruses replicate by converting their positive sense genomic RNA into double-stranded DNA that is subsequently integrated into the host genome. This conversion is catalyzed by reverse transcriptase (RT) early after virus entry into the target ce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b2c938539835ed60f07f9ee675ced79
http://europepmc.org/articles/PMC2367716