In vitro oxidative decarboxylation of free fatty acids to terminal alkenes by two new P450 peroxygenases

Autor: Huifang Xu, Linlin Ning, Wenxia Yang, Bo Fang, Cong Wang, Yun Wang, Jian Xu, Severine Collin, Frederic Laeuffer, Laurent Fourage, Shengying Li

Publikováno v: Biotechnology for Biofuels, Vol 10, Iss 1, Pp 1-15 (2017)

Abstract Background P450 fatty acid decarboxylases represented by the unusual CYP152 peroxygenase family member OleTJE have been receiving great attention recently since these P450 enzymes are able to catalyze the simple and direct production of 1-al

Externí odkaz: https://doaj.org/article/a29f7a6630c2436485be688f6c4808c6

Characterization of the Bubblegum acyl-CoA synthetase of Microchloropsis gaditana

Autor: Fabrice Rébeillé, Mariette Bedhomme, Juliette Jouhet, Laurent Poulet, Sébastien Leterme, Serge Crouzy, Séverine Collin, Renaud Dumas, Frédéric Laueffer, Eric Maréchal, Alberto Amato, Laurent Fourage, Morgane Michaud, Elodie Billey, Leonardo Magneschi, Amélie Andres-Robin, Giovanni Finazzi

Publikováno v: Plant Physiology
Plant Physiology, American Society of Plant Biologists, 2021, 185 (3), pp.815-835. ⟨10.1093/plphys/kiaa110⟩
Plant Physiology, 2021, 185 (3), pp.815-835. ⟨10.1093/plphys/kiaa110⟩
Plant Physiol

The metabolic pathways of glycerolipids are well described in cells containing chloroplasts limited by a two-membrane envelope but not in cells containing plastids limited by four membranes, including heterokonts. Fatty acids (FAs) produced in the pl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b1901c39109b1d80fc096e5de2063c8
https://hal.archives-ouvertes.fr/hal-03185953

Directed Evolution of P450 Fatty Acid Decarboxylases via High-Throughput Screening Towards Improved Catalytic Activity

Autor: Huifang Xu, Weinan Liang, Linlin Ning, Yuanyuan Jiang, Wenxia Yang, Cong Wang, Feifei Qi, Li Ma, Lei Du, Laurent Fourage, Yongjin J. Zhou, Shengying Li

P450 fatty acid decarboxylases (FADCs) have recently been attracting considerable attention owing to their one-step direct production of industrially important 1-alkenes from biologically abundant feedstock free fatty acids under mild conditions. How

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7db3384641ea6591cbb89e2852f8d8f1
https://doi.org/10.26434/chemrxiv.9791162

Nitric Oxide Mediates Nitrite-Sensing and Acclimation and Triggers a Remodeling of Lipids

Autor: Fabrice Rébeillé, Mariette Bedhomme, Leonardo Magneschi, Laurent Fourage, Juliette Jouhet, Michael Reith, Séverine Collin, Eric Maréchal, Lina-Juana Dolch, Frédéric Laeuffer, Christelle Richard, Josselin Lupette, Guillaume Tourcier, Melissa Conte, Patrick J. McGinn, Khawla Seddiki, Robert S. Richards, Erwan Corre

Publikováno v: Plant Physiology
Plant Physiology, American Society of Plant Biologists, 2017, 175 (3), pp.1407-1423. ⟨10.1104/pp.17.01042⟩
Plant Physiology, 2017, 175 (3), pp.1407-1423. ⟨10.1104/pp.17.01042⟩

International audience; Nitric oxide (NO) is an intermediate of the nitrogen cycle, an industrial pollutant, and a marker of climate change. NO also acts as a gaseous transmitter in a variety of biological processes. The impact of environmental NO ne

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d6a010ffc3ab2d8fe6d1340abb243b7
https://pubmed.ncbi.nlm.nih.gov/28924015

Directed evolution of a 13-hydroperoxide lyase (CYP74B) for improved process performance

Autor: Christophe Ullmann, Pascal Auffray, Denis Wahler, Laurent Fourage, Bojan Bosijokovic, Fredi Brühlmann

Publikováno v: Journal of Biotechnology. 163:339-345

The performance of a 13-hydroperoxide lyase from guava, an enzyme of the CYP74 family, which is of interest for the industrial production of saturated and unsaturated C6-aldehydes and their derivatives, was improved by directed evolution. Four rounds

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::437581755b4795ed2779d50410390064
https://doi.org/10.1016/j.jbiotec.2012.11.005