Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Laurent Debelle"'
Autor:
Azzam Alwan, Remi Cogranne, Pierre Beauseroy, Edith Grall-Maes, Nicolas Belloy, Laurent Debelle, Stephanie Baud, Manuel Dauchez, Sebastien Almagro
Publikováno v:
IEEE Access, Vol 9, Pp 92143-92156 (2021)
Over the past decades, the understanding of peptides and proteins biological functions has been an active research topic. Latest research works in this field have suggested that protein conformations may be a key feature for gaining insights into pro
Externí odkaz:
https://doaj.org/article/67b6802432f44a2b8774289c3bc36cd3
Autor:
Aïcha Ben Zemzem, Xiaowen Liang, Laetitia Vanalderwiert, Camille Bour, Béatrice Romier-Crouzet, Sébastien Blaise, Michael J. Sherratt, Timm Weitkamp, Manuel Dauchez, Stéphanie Baud, Nicolas Passat, Laurent Debelle, Sébastien Almagro
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 6, p 3250 (2022)
Diabetes is a major concern of our society as it affects one person out of 11 around the world. Elastic fiber alterations due to diabetes increase the stiffness of large arteries, but the structural effects of these alterations are poorly known. To a
Externí odkaz:
https://doaj.org/article/28a8d164267447cdb74f933e8ed65d67
Autor:
Stéphanie Salesse, Ludivine Odoul, Lise Chazée, Christian Garbar, Laurent Duca, Laurent Martiny, Rachid Mahmoudi, Laurent Debelle
Publikováno v:
FEBS Open Bio, Vol 8, Iss 9, Pp 1395-1404 (2018)
Elastin is a long‐lived extracellular matrix protein responsible for the structural integrity and function of tissues. Breast cancer elastosis is a complex phenomenon resulting in both the deposition of elastotic masses and the local production of
Externí odkaz:
https://doaj.org/article/a300ea84e9b34671a29e803c667abaf9
Autor:
Amandine Scandolera, Fanja Rabenoelina, Carine Chaintreuil, Anthony Rusciani, Pascal Maurice, Sébastien Blaise, Béatrice Romier-Crouzet, Hassan El Btaouri, Laurent Martiny, Laurent Debelle, Laurent Duca
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0129994 (2015)
Degradation of elastin leads to the production of elastin-derived peptides (EDP), which exhibit several biological effects, such as cell proliferation or protease secretion. Binding of EDP on the elastin receptor complex (ERC) triggers lactosylcerami
Externí odkaz:
https://doaj.org/article/ebcb4043105e4e7a834a93ab7ff495dd
Autor:
Anthony Rusciani, Laurent Duca, Hervé Sartelet, Aurore Chatron-Colliet, Hélène Bobichon, Dominique Ploton, Richard Le Naour, Sébastien Blaise, Laurent Martiny, Laurent Debelle
Publikováno v:
PLoS ONE, Vol 5, Iss 11, p e14010 (2010)
The sialidase activity of neuraminidase-1 (Neu-1) is responsible for ERK 1/2 pathway activation following binding of elastin peptide on the elastin receptor complex. In this work, we demonstrate that the receptor and lipid rafts colocalize at the pla
Externí odkaz:
https://doaj.org/article/85aa4021985a40a18ad35a16f532cbe4
Autor:
Micheal J Sherratt, Aurelien Pitois, Laure Bernard, Caroline Ringenbach, Philippe Mondon, Olivier Peschard, Richard Leroux, Carol Courage, Yegor Doush, Eleanor Bradley, Mike Bell, Laurent Debelle, Leo Zeef, Andrew Gilmore, Bezaleel Mambwe, Rachel Watson, Alex Eckersley, Matiss Ozols, Nathan Jariwala
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::958bd762ecebf8a859a60659cb126551
https://doi.org/10.26226/m.6437c125d44f9e0012ceb0d6
https://doi.org/10.26226/m.6437c125d44f9e0012ceb0d6
Autor:
Nathan Jariwala, Matiss Ozols, Alexander Eckersley, Bezaleel Mambwe, Rachel E B Watson, Leo Zeef, Andrew Gilmore, Laurent Debelle, Mike Bell, Eleanor J Bradley, Yegor Doush, Carole Courage, Richard Leroux, Olivier Peschard, Philippe Mondon, Caroline Ringenbach, Laure Bernard, Aurelien Pitois, Michael J Sherratt
SummaryThe exogenous application of small peptides can beneficially affect clinical skin appearance (wrinkles) and architecture (collagen and elastic fibre deposition and epidermal thickness). However, the discovery of new bioactive peptides has not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f21f7c1d59541699e4594c89d09a0dc5
https://doi.org/10.1101/2023.03.17.533127
https://doi.org/10.1101/2023.03.17.533127
Autor:
Almagro, Aïcha Ben Zemzem, Xiaowen Liang, Laetitia Vanalderwiert, Camille Bour, Béatrice Romier-Crouzet, Sébastien Blaise, Michael J. Sherratt, Timm Weitkamp, Manuel Dauchez, Stéphanie Baud, Nicolas Passat, Laurent Debelle, Sébastien
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 6; Pages: 3250
Diabetes is a major concern of our society as it affects one person out of 11 around the world. Elastic fiber alterations due to diabetes increase the stiffness of large arteries, but the structural effects of these alterations are poorly known. To a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::9f68ede871c7f1e40a7de45673b85507
Autor:
Aïcha, Ben Zemzem, Aline, Genevaux, Amandine, Wahart, Andrew J, Bodey, Sébastien, Blaise, Béatrice, Romier-Crouzet, Jessica, Jonquet, Camille, Bour, Rémi, Cogranne, Pierre, Beauseroy, Manuel, Dauchez, Michael J, Sherratt, Laurent, Debelle, Sébastien, Almagro
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental BiologyREFERENCES. 35(10)
The arterial wall consists of three concentric layers: intima, media, and adventitia. Beyond their resident cells, these layers are characterized by an extracellular matrix (ECM), which provides both biochemical and mechanical support. Elastin, the m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d514f75777de15fea52e17256eae46b0
https://pubmed.ncbi.nlm.nih.gov/34473371
https://pubmed.ncbi.nlm.nih.gov/34473371
Autor:
Nathan Jariwala, Matiss Ozols, Mike Bell, Eleanor Bradley, Andrew Gilmore, Laurent Debelle, Michael J. Sherratt
Publikováno v:
Advanced Drug Delivery Reviews. 185:114240
Extracellular matrix (ECM) proteins confer biomechanical properties, maintain cell phenotype and mediate tissue repair (via release of sequestered cytokines and proteases). In contrast to intracellular proteomes, where proteins are monitored and repl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cfd429d925f7bc2aa970d05e34f8b11
https://doi.org/10.1016/j.addr.2022.114240
https://doi.org/10.1016/j.addr.2022.114240