Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Laurent Debéthune"'
Autor:
Laurent Debéthune, Joan Casals, Keith R. Fox, and Anna Grandas, Karine Alvarez, Enrique Pedroso, Antonina Risitano
Publikováno v:
Bioconjugate Chemistry. 17:1351-1359
Conjugates containing quadruplex-stabilizing acridines linked to oligonucleotides that are complementary to the G-rich human telomere sequence were synthesized. Acylation of 3,6-diaminoacridine followed by two Michael reactions provided derivatives s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01526bd9f07e6d6da5fb378212c32c61
https://doi.org/10.1021/bc060194t
https://doi.org/10.1021/bc060194t
Publikováno v:
Tetrahedron. 60:5461-5469
The hybridization properties of various peptide–oligonucleotide hybrids were assessed from UV thermal denaturation experiments. Analysis of these and other published data suggests that peptide chains, both hydrophobic and positively charged, genera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66c96900ef16b2a0f32cd68d8e24e997
https://doi.org/10.1016/j.tet.2004.04.053
https://doi.org/10.1016/j.tet.2004.04.053
Publikováno v:
Nucleic Acids Research. 30:1198-1204
Tyrosyl-DNA phosphodiesterase-1 (Tdp1) is the only known enzyme to remove tyrosine from complexes in which the amino acid is linked to the 3′-end of DNA fragments. Such complexes can be produced following DNA processing by topoisomerase I, and rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ee91262a5e2bd156840f9a58fad3ab9
https://doi.org/10.1093/nar/30.5.1198
https://doi.org/10.1093/nar/30.5.1198
Autor:
Jose J Pastor, Anna Grandas, Montse Cruz, Miriam Royo, Ernest Giralt, Francesc Rabanal, Fernando Albericio, Enrique Pedroso, Vicente Marchán, Ramon Eritja, Laurent Debéthune
Publikováno v:
Synthetic Communications. 31:225-232
The optimization of a synthetic process for the preparation of HMFS handle, which is used for the solid-phase synthesis of peptides and oligonucleotides, is presented.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea83de20759e7a35aa181bb9e14e2073
https://doi.org/10.1081/scc-100000203
https://doi.org/10.1081/scc-100000203
Autor:
Vicente Marchán, I. Travesset, Maite Beltrán, Jordi Robles, Enrique Pedroso, A. Grandas, G. Fábregas, Laurent Debéthune
Publikováno v:
Nucleosides and Nucleotides. 18:1493-1494
The preparation of nucleopeptides containing tryptophan and basic residues (lysine, arginine) is described. Different solid supports and the necessity of primary carboxamide protection have also been evaluated.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1dd858a79884eefcbf9b74b40c28b57b
https://doi.org/10.1080/07328319908044765
https://doi.org/10.1080/07328319908044765